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The map label for this gene is trpGD [H]

Identifier: 148643205

GI number: 148643205

Start: 1123808

End: 1124389

Strand: Reverse

Name: trpGD [H]

Synonym: Msm_1145

Alternate gene names: 148643205

Gene position: 1124389-1123808 (Counterclockwise)

Preceding gene: 148643206

Following gene: 148643204

Centisome position: 60.67

GC content: 28.87

Gene sequence:

>582_bases
ATGATTTTATTAATAGATAACTATGATAGCTTTTCATATAATTTATATCAATTAATCGGACAGGTAAATAGGGATATTGA
AGTTTATAGAAATGATAAAATCACTGCTGATGAAATTAAAGATTTAAATCCTGAAGCTATTATTTTATCTCCAGGTCCTG
GAAGGCCTGAAGATGCGGGAATCTGTGTTGATGTTGTTAGGAAATTTTATGATAAAATACCAATTTTGGGAGTTTGTCTT
GGACATCAGGCAATATGTGATGCATTTGGAGGTAAAATATCTTATGCCAGCAAATTAATGCATGGAAAATCATCAACAGC
TAAATTAAATAAAGACCCTATTTTTAAAGGTTTAAATGATGAGATTGCTGTTGGAAGATATCATTCTTTAAGTTTGGTTG
AAAATACTTTGCCTAAAGATTTAAAAATAATTTCAAAAACAGCAGACAACGGAGAAATAATGGCGATTAAACATAAAAAA
TATAATGTTTACGGTCTTCAATTTCATCCGGAATCAATATTAACACCTGACGGAATTACAATAATTGAAAATTTCATAAA
CAAAATTAAGGAGGATAATTAA

Upstream 100 bases:

>100_bases
GAATTGTAGCTGACAGTGTTCCGGATAATGAATTTGACGAGTGTTTAAATAAAGCAGCAGCAGTTATTGATGCTTTAAAA
ATAGCTGACGGGGGAATTTT

Downstream 100 bases:

>100_bases
ATGATTAAGGAAGCTATTTTAAAAGTTGTAAATGGAAATGACTTAAATGCGAAGGAAGCTTATGGGGCAATGGATGAAAT
AATGTCCGGAGAATCTAGTG

Product: anthranilate/para-aminobenzoate synthase component II, TrpG

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MILLIDNYDSFSYNLYQLIGQVNRDIEVYRNDKITADEIKDLNPEAIILSPGPGRPEDAGICVDVVRKFYDKIPILGVCL
GHQAICDAFGGKISYASKLMHGKSSTAKLNKDPIFKGLNDEIAVGRYHSLSLVENTLPKDLKIISKTADNGEIMAIKHKK
YNVYGLQFHPESILTPDGITIIENFINKIKEDN

Sequences:

>Translated_193_residues
MILLIDNYDSFSYNLYQLIGQVNRDIEVYRNDKITADEIKDLNPEAIILSPGPGRPEDAGICVDVVRKFYDKIPILGVCL
GHQAICDAFGGKISYASKLMHGKSSTAKLNKDPIFKGLNDEIAVGRYHSLSLVENTLPKDLKIISKTADNGEIMAIKHKK
YNVYGLQFHPESILTPDGITIIENFINKIKEDN
>Mature_193_residues
MILLIDNYDSFSYNLYQLIGQVNRDIEVYRNDKITADEIKDLNPEAIILSPGPGRPEDAGICVDVVRKFYDKIPILGVCL
GHQAICDAFGGKISYASKLMHGKSSTAKLNKDPIFKGLNDEIAVGRYHSLSLVENTLPKDLKIISKTADNGEIMAIKHKK
YNVYGLQFHPESILTPDGITIIENFINKIKEDN

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=46.8085106382979, Blast_Score=197, Evalue=3e-52,
Organism=Escherichia coli, GI1787517, Length=193, Percent_Identity=37.8238341968912, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1788854, Length=198, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786215, Length=162, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133901714, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992710, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992717, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=49.1978609625668, Blast_Score=197, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=30.1435406698565, Blast_Score=85, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323873, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21568; Mature: 21568

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFSYNLYQLIGQVNRDIEVYRNDKITADEIKDLNPEAIILSPGPGRPEDAG
CEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCEEEECCCCCCCCCCC
ICVDVVRKFYDKIPILGVCLGHQAICDAFGGKISYASKLMHGKSSTAKLNKDPIFKGLND
HHHHHHHHHHHCCCEEEEHHCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EIAVGRYHSLSLVENTLPKDLKIISKTADNGEIMAIKHKKYNVYGLQFHPESILTPDGIT
CEEECCHHHHHHHHHCCCHHHHHHEECCCCCCEEEEEECCEEEEEEEECCCCCCCCCCHH
IIENFINKIKEDN
HHHHHHHHHCCCC
>Mature Secondary Structure
MILLIDNYDSFSYNLYQLIGQVNRDIEVYRNDKITADEIKDLNPEAIILSPGPGRPEDAG
CEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCEEEECCCCCCCCCCC
ICVDVVRKFYDKIPILGVCLGHQAICDAFGGKISYASKLMHGKSSTAKLNKDPIFKGLND
HHHHHHHHHHHCCCEEEEHHCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EIAVGRYHSLSLVENTLPKDLKIISKTADNGEIMAIKHKKYNVYGLQFHPESILTPDGIT
CEEECCHHHHHHHHHCCCHHHHHHEECCCCCCEEEEEECCEEEEEEEECCCCCCCCCCHH
IIENFINKIKEDN
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]