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The map label for this gene is trpD

Identifier: 148643204

GI number: 148643204

Start: 1122800

End: 1123807

Strand: Reverse

Name: trpD

Synonym: Msm_1144

Alternate gene names: 148643204

Gene position: 1123807-1122800 (Counterclockwise)

Preceding gene: 148643205

Following gene: 148643203

Centisome position: 60.64

GC content: 36.41

Gene sequence:

>1008_bases
ATGATTAAGGAAGCTATTTTAAAAGTTGTAAATGGAAATGACTTAAATGCGAAGGAAGCTTATGGGGCAATGGATGAAAT
AATGTCCGGAGAATCTAGTGAGGTTCAGATGAGTGCTTATTTAACTGCACTGTCAATGAAAGGTGAAACAATTGAAGAAA
TCACAGCTTCTACAAAAGCCATGAGGGCTCATTGTGTTAAATTACTAAATGATGAAGAAGTCTTGGAAATAGTTGGAACT
GGTGGAGACGGATCCAACACTTTCAACATATCAACAACATCTTCAATTGTAATTTCTGCAGCAGGAGTTCCGGTAGCCAA
ACATGGAAACAGATCAGCATCAAGCAAATGTGGGGCGGCAGATGTTTTGGAAGCTTTAGGTGTAAATATTTATATTGAAC
CGGAAAAAAGCTTGAAAATATTAAAAGAGATTAATCTGTGCTTTTTATTTGCTCAAAATTATCATTTGGCCATGAAATTT
GTAGCTGGAGTCAGAAAAGAATTATCTATAAGAACAATTTTCAATATTCTGGGGCCTCTGACAAATCCTGCAGGTGCTAC
AATGCAGGTTTTGGGGGTTTATGATGAATCACTTGTGAAACCTCTTTGTGAAGTGCTTAAAAACGTAGGAGTTAAGTCTG
CATTATCAGTATACGGTCAGGACGGATTGGATGAAATTTCAGTTAGTGACAAAACATCTGTTTGTGAACTTAGGGACGGC
AGGTTAAAATGTTATGAAATAGCTCCTGAAGATTTTGGAATGGAGAGATGTTCTAAAGAAGACCTTGTAGGTGGAAATCC
TAGGGAAAATGCAGAAATTACATTATCTATTTTAAATGGCCAAAAAGGACCTAAAAGAAATGCCGTAGTTTTAAACTCTG
CAGCTGCTTTATATGTTGCAGGAAAAGCAGATTCTATAGAAGATGGTGTTAGATTAGCCAGTGAAATTATTGATTCTGGC
AGGGCTAAAAAACAGCTTGAAAAATTCATCGAATATACAAACAGTTGA

Upstream 100 bases:

>100_bases
TAATGTTTACGGTCTTCAATTTCATCCGGAATCAATATTAACACCTGACGGAATTACAATAATTGAAAATTTCATAAACA
AAATTAAGGAGGATAATTAA

Downstream 100 bases:

>100_bases
TTTCATGTTAGATAAAATAGTTGAAAAAACAAAAGAAAGAGTATCTGAAAATAAAAAGGTTAATTCATTAGACAGACTCA
AATATAAAATACTCAATATT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MIKEAILKVVNGNDLNAKEAYGAMDEIMSGESSEVQMSAYLTALSMKGETIEEITASTKAMRAHCVKLLNDEEVLEIVGT
GGDGSNTFNISTTSSIVISAAGVPVAKHGNRSASSKCGAADVLEALGVNIYIEPEKSLKILKEINLCFLFAQNYHLAMKF
VAGVRKELSIRTIFNILGPLTNPAGATMQVLGVYDESLVKPLCEVLKNVGVKSALSVYGQDGLDEISVSDKTSVCELRDG
RLKCYEIAPEDFGMERCSKEDLVGGNPRENAEITLSILNGQKGPKRNAVVLNSAAALYVAGKADSIEDGVRLASEIIDSG
RAKKQLEKFIEYTNS

Sequences:

>Translated_335_residues
MIKEAILKVVNGNDLNAKEAYGAMDEIMSGESSEVQMSAYLTALSMKGETIEEITASTKAMRAHCVKLLNDEEVLEIVGT
GGDGSNTFNISTTSSIVISAAGVPVAKHGNRSASSKCGAADVLEALGVNIYIEPEKSLKILKEINLCFLFAQNYHLAMKF
VAGVRKELSIRTIFNILGPLTNPAGATMQVLGVYDESLVKPLCEVLKNVGVKSALSVYGQDGLDEISVSDKTSVCELRDG
RLKCYEIAPEDFGMERCSKEDLVGGNPRENAEITLSILNGQKGPKRNAVVLNSAAALYVAGKADSIEDGVRLASEIIDSG
RAKKQLEKFIEYTNS
>Mature_335_residues
MIKEAILKVVNGNDLNAKEAYGAMDEIMSGESSEVQMSAYLTALSMKGETIEEITASTKAMRAHCVKLLNDEEVLEIVGT
GGDGSNTFNISTTSSIVISAAGVPVAKHGNRSASSKCGAADVLEALGVNIYIEPEKSLKILKEINLCFLFAQNYHLAMKF
VAGVRKELSIRTIFNILGPLTNPAGATMQVLGVYDESLVKPLCEVLKNVGVKSALSVYGQDGLDEISVSDKTSVCELRDG
RLKCYEIAPEDFGMERCSKEDLVGGNPRENAEITLSILNGQKGPKRNAVVLNSAAALYVAGKADSIEDGVRLASEIIDSG
RAKKQLEKFIEYTNS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=275, Percent_Identity=40, Blast_Score=211, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6320561, Length=328, Percent_Identity=32.3170731707317, Blast_Score=149, Evalue=6e-37,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_METS3 (A5UMC1)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273717.1
- ProteinModelPortal:   A5UMC1
- SMR:   A5UMC1
- STRING:   A5UMC1
- GeneID:   5216078
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_1144
- eggNOG:   arNOG05391
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35893; Mature: 35893

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEAILKVVNGNDLNAKEAYGAMDEIMSGESSEVQMSAYLTALSMKGETIEEITASTKA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHH
MRAHCVKLLNDEEVLEIVGTGGDGSNTFNISTTSSIVISAAGVPVAKHGNRSASSKCGAA
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCEEEEEECCCCEECCCCCCCCCCCCHH
DVLEALGVNIYIEPEKSLKILKEINLCFLFAQNYHLAMKFVAGVRKELSIRTIFNILGPL
HHHHHCCCEEEECCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TNPAGATMQVLGVYDESLVKPLCEVLKNVGVKSALSVYGQDGLDEISVSDKTSVCELRDG
CCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCC
RLKCYEIAPEDFGMERCSKEDLVGGNPRENAEITLSILNGQKGPKRNAVVLNSAAALYVA
CEEEEEECCHHCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCEEEEEE
GKADSIEDGVRLASEIIDSGRAKKQLEKFIEYTNS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKEAILKVVNGNDLNAKEAYGAMDEIMSGESSEVQMSAYLTALSMKGETIEEITASTKA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHH
MRAHCVKLLNDEEVLEIVGTGGDGSNTFNISTTSSIVISAAGVPVAKHGNRSASSKCGAA
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCEEEEEECCCCEECCCCCCCCCCCCHH
DVLEALGVNIYIEPEKSLKILKEINLCFLFAQNYHLAMKFVAGVRKELSIRTIFNILGPL
HHHHHCCCEEEECCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TNPAGATMQVLGVYDESLVKPLCEVLKNVGVKSALSVYGQDGLDEISVSDKTSVCELRDG
CCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCC
RLKCYEIAPEDFGMERCSKEDLVGGNPRENAEITLSILNGQKGPKRNAVVLNSAAALYVA
CEEEEEECCHHCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCEEEEEE
GKADSIEDGVRLASEIIDSGRAKKQLEKFIEYTNS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA