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The map label for this gene is gch3

Identifier: 148643033

GI number: 148643033

Start: 935142

End: 935906

Strand: Reverse

Name: gch3

Synonym: Msm_0973

Alternate gene names: 148643033

Gene position: 935906-935142 (Counterclockwise)

Preceding gene: 148643034

Following gene: 148643032

Centisome position: 50.5

GC content: 32.55

Gene sequence:

>765_bases
ATGATACAAATGACTTTAATACAAATTGATAATTATGGTCCATGGACTGTAACTCCAAGACCACGTAATGAATCAGATTT
ACAAATTTTACAGGCAGAATTATATGCAGATTTAGAAAGGCAATTTGCAAATAAGAAAGGATTAGTTTTCTTTACTAGAT
TTGATAATTTACTTGCTGTTACAAACGGTATTGATGAGGAAGACCACTTGAGGATTCAAAGATCTATTAGAAATAGATAT
CCAATTACTATTAGTATGGGTGTTGGGGCGGCTGAAACTCCTCATGAAGCTCAAAAATTAGCTACTATTGCTTTACAAAA
AGAAGGTGGAGCTCAATCTTCAAAAAGAAAAGAAATTTTAGCTATTGATAGTTTAGCTCCAGCAGATGAAAATAATTTGG
TTCAGGCAGCACATATTGATATTAATAGTGTTACAGAAACATTGACTGATATTGAATCTGCATTTGACACTAATTTCATG
GTTAATAAAGCACAGCATTATTTAATGACTAAATTAATTAAAAAAGGAGCATTACTGTTCTTCATTGGTGGAGATAACTT
CATGGCTCCATGTAATGGATTGTCTGAAAAGGAAATTGAAGATATTTTAGTTGAAATCAATGATGAAATTGGAATTGGTC
TTAAAGCAGGTATTGGTGTTGGCCGCAATATGGAAGATGCTGCATATATGGCTGATTTGGGACTTGAAGAAATCCGTGAT
CATGATAATGGAATGTGGACATGGGTTATTGAAAAAGAATATTAA

Upstream 100 bases:

>100_bases
AAGTAATTGTTACAAATACAATTATGAAAAATTTAGATGATAAGAAAAAATTAGCTAAAATAATCTTAAATGATATTTCT
TAGGGAAAATGGTGGCTTAA

Downstream 100 bases:

>100_bases
GGGGGCTTCTAAATTAAAGTCATAGCTCCAATGGCTGGAATAACTGATGCTGAATTTTTAAATAAGGTTATTCCATTTGG
ATTTGACACAGCTACATTAG

Product: GTP cyclohydrolase III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MIQMTLIQIDNYGPWTVTPRPRNESDLQILQAELYADLERQFANKKGLVFFTRFDNLLAVTNGIDEEDHLRIQRSIRNRY
PITISMGVGAAETPHEAQKLATIALQKEGGAQSSKRKEILAIDSLAPADENNLVQAAHIDINSVTETLTDIESAFDTNFM
VNKAQHYLMTKLIKKGALLFFIGGDNFMAPCNGLSEKEIEDILVEINDEIGIGLKAGIGVGRNMEDAAYMADLGLEEIRD
HDNGMWTWVIEKEY

Sequences:

>Translated_254_residues
MIQMTLIQIDNYGPWTVTPRPRNESDLQILQAELYADLERQFANKKGLVFFTRFDNLLAVTNGIDEEDHLRIQRSIRNRY
PITISMGVGAAETPHEAQKLATIALQKEGGAQSSKRKEILAIDSLAPADENNLVQAAHIDINSVTETLTDIESAFDTNFM
VNKAQHYLMTKLIKKGALLFFIGGDNFMAPCNGLSEKEIEDILVEINDEIGIGLKAGIGVGRNMEDAAYMADLGLEEIRD
HDNGMWTWVIEKEY
>Mature_254_residues
MIQMTLIQIDNYGPWTVTPRPRNESDLQILQAELYADLERQFANKKGLVFFTRFDNLLAVTNGIDEEDHLRIQRSIRNRY
PITISMGVGAAETPHEAQKLATIALQKEGGAQSSKRKEILAIDSLAPADENNLVQAAHIDINSVTETLTDIESAFDTNFM
VNKAQHYLMTKLIKKGALLFFIGGDNFMAPCNGLSEKEIEDILVEINDEIGIGLKAGIGVGRNMEDAAYMADLGLEEIRD
HDNGMWTWVIEKEY

Specific function: Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity

COG id: COG2429

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type GTP cyclohydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH3_METS3 (A5ULV0)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273546.1
- ProteinModelPortal:   A5ULV0
- SMR:   A5ULV0
- STRING:   A5ULV0
- GeneID:   5216943
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0973
- eggNOG:   arNOG04785
- HOGENOM:   HBG497452
- OMA:   FIGGDNF
- ProtClustDB:   PRK02240
- HAMAP:   MF_00608
- InterPro:   IPR007839
- PIRSF:   PIRSF009265
- ProDom:   PD313320

Pfam domain/function: PF05165 GGDN

EC number: =3.5.4.29

Molecular weight: Translated: 28459; Mature: 28459

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQMTLIQIDNYGPWTVTPRPRNESDLQILQAELYADLERQFANKKGLVFFTRFDNLLAV
CEEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEE
TNGIDEEDHLRIQRSIRNRYPITISMGVGAAETPHEAQKLATIALQKEGGAQSSKRKEIL
ECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHEEEECCCCCCCCCCCEEE
AIDSLAPADENNLVQAAHIDINSVTETLTDIESAFDTNFMVNKAQHYLMTKLIKKGALLF
EECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEE
FIGGDNFMAPCNGLSEKEIEDILVEINDEIGIGLKAGIGVGRNMEDAAYMADLGLEEIRD
EECCCCEECCCCCCCHHHHHHHHEEECCCCCCEEEECCCCCCCCHHHHHHHHCCHHHHHC
HDNGMWTWVIEKEY
CCCCEEEEEEEECC
>Mature Secondary Structure
MIQMTLIQIDNYGPWTVTPRPRNESDLQILQAELYADLERQFANKKGLVFFTRFDNLLAV
CEEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEE
TNGIDEEDHLRIQRSIRNRYPITISMGVGAAETPHEAQKLATIALQKEGGAQSSKRKEIL
ECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHEEEECCCCCCCCCCCEEE
AIDSLAPADENNLVQAAHIDINSVTETLTDIESAFDTNFMVNKAQHYLMTKLIKKGALLF
EECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEE
FIGGDNFMAPCNGLSEKEIEDILVEINDEIGIGLKAGIGVGRNMEDAAYMADLGLEEIRD
EECCCCEECCCCCCCHHHHHHHHEEECCCCCCEEEECCCCCCCCHHHHHHHHCCHHHHHC
HDNGMWTWVIEKEY
CCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA