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The map label for this gene is cofD [H]

Identifier: 148643034

GI number: 148643034

Start: 935924

End: 936829

Strand: Reverse

Name: cofD [H]

Synonym: Msm_0974

Alternate gene names: 148643034

Gene position: 936829-935924 (Counterclockwise)

Preceding gene: 148643035

Following gene: 148643033

Centisome position: 50.55

GC content: 30.46

Gene sequence:

>906_bases
ATGATTACTGTACTGTCTGGGGGAACTGGAACTCCAAAATTATTACAAGGTTTAAAAGAAGTTATTGATCCTAAAGATAT
TACTATTGTTGTCAATACTTTAGAAAATGAATATTTTTCAGGTGTTTATGTGTCAGCAGACATTGACACGGTATTGTACA
CTATGGCTGATATGATTAATGAAGAATTTTGGTATGGTGTTAAAGATGATACATTTATCACTCATGAAAGGCTTGAAGAA
TTAGGCACTCCGGAGTTGCTTAGGATAGGAGATATTGATAGAGCTACTAAAATACAAAAGACTCTATTGATGGAAAATCA
TTCACTTGCTGAAGCTGTTGATATTCAGGCAAATAATATGCATATCCCTTCCAAAATTTTACCTATGAGTAATGAAAATT
CAGATATTAAAATCATTACAGACATCGGTGAATTGGAATTTCATGACTTTTTAATAAAACATCAGTGCAATCCTGAAGTT
TTGGATGTCAAATTTTCCAAAGTGACTCCTGCGGAAGGGATTATTGATGCTATTAATAATTCTGATGCAGTTATTATTGG
ACCATCTAATCCGATAACTTCAATATCTCCAATATTGTCTTTAGATGGAGTTAAAGAAGCTTTGGAAAATACTCATGTAA
TAGCAGTTTCTCCAATTATTGGTACTGATTCAGTAAGTGGTCCGGCCAGTAAATTTATGGATGCACTTGGAATTGAAGTT
TCATCATTAGGTGTTGCTTCTTTATATGAAAGTTTTTTAGATACGATTGTTATTGACAAAAAAGATAATAATTTAAAGGA
TGATTTAGAAAAAATTGTTAGTGAAGTAATTGTTACAAATACAATTATGAAAAATTTAGATGATAAGAAAAAATTAGCTA
AAATAATCTTAAATGATATTTCTTAG

Upstream 100 bases:

>100_bases
TAATTTTGATAAATTAAGAGATACGAAAACCGGAATTAATCCATTACTTAGACCAAAAGAATTTGACGTATTTAGAAATT
AGTCTGGAGATTAAATTAAT

Downstream 100 bases:

>100_bases
GGAAAATGGTGGCTTAAATGATACAAATGACTTTAATACAAATTGATAATTATGGTCCATGGACTGTAACTCCAAGACCA
CGTAATGAATCAGATTTACA

Product: LPPG:FO 2-phospho-L-lactate transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MITVLSGGTGTPKLLQGLKEVIDPKDITIVVNTLENEYFSGVYVSADIDTVLYTMADMINEEFWYGVKDDTFITHERLEE
LGTPELLRIGDIDRATKIQKTLLMENHSLAEAVDIQANNMHIPSKILPMSNENSDIKIITDIGELEFHDFLIKHQCNPEV
LDVKFSKVTPAEGIIDAINNSDAVIIGPSNPITSISPILSLDGVKEALENTHVIAVSPIIGTDSVSGPASKFMDALGIEV
SSLGVASLYESFLDTIVIDKKDNNLKDDLEKIVSEVIVTNTIMKNLDDKKKLAKIILNDIS

Sequences:

>Translated_301_residues
MITVLSGGTGTPKLLQGLKEVIDPKDITIVVNTLENEYFSGVYVSADIDTVLYTMADMINEEFWYGVKDDTFITHERLEE
LGTPELLRIGDIDRATKIQKTLLMENHSLAEAVDIQANNMHIPSKILPMSNENSDIKIITDIGELEFHDFLIKHQCNPEV
LDVKFSKVTPAEGIIDAINNSDAVIIGPSNPITSISPILSLDGVKEALENTHVIAVSPIIGTDSVSGPASKFMDALGIEV
SSLGVASLYESFLDTIVIDKKDNNLKDDLEKIVSEVIVTNTIMKNLDDKKKLAKIILNDIS
>Mature_301_residues
MITVLSGGTGTPKLLQGLKEVIDPKDITIVVNTLENEYFSGVYVSADIDTVLYTMADMINEEFWYGVKDDTFITHERLEE
LGTPELLRIGDIDRATKIQKTLLMENHSLAEAVDIQANNMHIPSKILPMSNENSDIKIITDIGELEFHDFLIKHQCNPEV
LDVKFSKVTPAEGIIDAINNSDAVIIGPSNPITSISPILSLDGVKEALENTHVIAVSPIIGTDSVSGPASKFMDALGIEV
SSLGVASLYESFLDTIVIDKKDNNLKDDLEKIVSEVIVTNTIMKNLDDKKKLAKIILNDIS

Specific function: Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F42

COG id: COG0391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002882
- InterPro:   IPR010115 [H]

Pfam domain/function: PF01933 UPF0052 [H]

EC number: NA

Molecular weight: Translated: 33007; Mature: 33007

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVLSGGTGTPKLLQGLKEVIDPKDITIVVNTLENEYFSGVYVSADIDTVLYTMADMIN
CEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHCCEEEECCHHHHHHHHHHHHH
EEFWYGVKDDTFITHERLEELGTPELLRIGDIDRATKIQKTLLMENHSLAEAVDIQANNM
HHHCCCCCCCCEEHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHEEECCCCE
HIPSKILPMSNENSDIKIITDIGELEFHDFLIKHQCNPEVLDVKFSKVTPAEGIIDAINN
ECCHHCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCC
SDAVIIGPSNPITSISPILSLDGVKEALENTHVIAVSPIIGTDSVSGPASKFMDALGIEV
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEECCCCCCCHHHHHHHHHCCCH
SSLGVASLYESFLDTIVIDKKDNNLKDDLEKIVSEVIVTNTIMKNLDDKKKLAKIILNDI
HHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
S
C
>Mature Secondary Structure
MITVLSGGTGTPKLLQGLKEVIDPKDITIVVNTLENEYFSGVYVSADIDTVLYTMADMIN
CEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHCCEEEECCHHHHHHHHHHHHH
EEFWYGVKDDTFITHERLEELGTPELLRIGDIDRATKIQKTLLMENHSLAEAVDIQANNM
HHHCCCCCCCCEEHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHEEECCCCE
HIPSKILPMSNENSDIKIITDIGELEFHDFLIKHQCNPEVLDVKFSKVTPAEGIIDAINN
ECCHHCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCC
SDAVIIGPSNPITSISPILSLDGVKEALENTHVIAVSPIIGTDSVSGPASKFMDALGIEV
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEECCCCCCCHHHHHHHHHCCCH
SSLGVASLYESFLDTIVIDKKDNNLKDDLEKIVSEVIVTNTIMKNLDDKKKLAKIILNDI
HHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]