Click here to switch to the map view.

The map label for this gene is fwdF [H]

Identifier: 148642843

GI number: 148642843

Start: 743686

End: 744693

Strand: Reverse

Name: fwdF [H]

Synonym: Msm_0783

Alternate gene names: 148642843

Gene position: 744693-743686 (Counterclockwise)

Preceding gene: 148642844

Following gene: 148642840

Centisome position: 40.19

GC content: 34.42

Gene sequence:

>1008_bases
ATGTTTAATGTTGAGAGGAGCGGGGAAGAAACCCGTAAGTTATCACATAACAATGATAGGTGTGTAGGTTGTGGAATTTG
TACTGATGTATGTCCTACATCTTCTTTGAGATTAGGACCTATTGTACCGATTGCACGTGGTTTAATTGAAATGGATTTAG
TTTCTGTAACTTCTAATACTTGTGTTTTATGCGGATTATGTTCTGTTGCATGTCCATTTGATGCTTTATCATTAACCATT
AACGGTAATGATATTAAAGAAACAGGAAATTATCCCGTATGGGAAGTTGAATCAGAAATTAATGATGATGATTGTATATA
CTGTGGAAGATGTTATTCTGTTTGTCCTAGAGACACTATCTTATTTAAAAGAGAGTTACCGTCTAGAGAAGATTTGGTTA
TTGGTGAAATCAGTGTCGATGAGGATAAATGTGTTTACTGTAGTATCTGTTCAGAAATGTGTCCTGCAGGAGCTATTAGT
TTAACTAATAATCCTGAGTTCTCTAATGACAATCTTAATAATACTATTGAAGTAGATACTTCCAAATGTATTTATTGTGG
TGTTTGTAAGAGGGCTTGTCCTCAAGATGCAATTAAAGCAGTATGTTCAACATGTATGCTTCAAGATCAAATTAAAGCTC
CTGAAATTAATGGTACTGCATCCATTCTTAAGGATGGCTGTGTAAACTGTTCTTGGTGTAAAGAAGTTTGTCCTGTTGAT
ACAATTAATGTAACCAAACCGTTTGAAGGAACTTTAAAACTGGTTGAAACAGATGAATCAACATGTAAAGGGGACGCCTG
CCACGCATGTCAAGATGTTTGTCCATGTGATGCAGTAGAAATTATTGACAATAAGGCAACTATTAATTTAGATTACTGTA
ATTTATGTGGTGCCTGTGTCAATGCATGTCCACAAAACATTAGGGAAGTCACAAGAACTTCAATGAAATTAAATAATATC
AACTCCGAATCCTGGAGAGATATTTTAACTTCTAATCTTTTAAGTTAG

Upstream 100 bases:

>100_bases
AAGATGGCGATGTAACTATTGTCCCTGAAAAATGCGATGACTGTGACCTTTGTATCCAAAACTGTCCTAATCAAGCTATA
TCTAAAGCATGAGGGATTTT

Downstream 100 bases:

>100_bases
AAAGAGAGATTTTACGCTCTTCTTTCTAAATTTTATTTATTAAAAAATTTCTTTCTTTTGTTATTGCTGTTTTTAATTTG
TTTTGAGTAGTGTCTGTTAT

Product: tungsten formylmethanofuran dehydrogenase, subunit F, FwdF

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MFNVERSGEETRKLSHNNDRCVGCGICTDVCPTSSLRLGPIVPIARGLIEMDLVSVTSNTCVLCGLCSVACPFDALSLTI
NGNDIKETGNYPVWEVESEINDDDCIYCGRCYSVCPRDTILFKRELPSREDLVIGEISVDEDKCVYCSICSEMCPAGAIS
LTNNPEFSNDNLNNTIEVDTSKCIYCGVCKRACPQDAIKAVCSTCMLQDQIKAPEINGTASILKDGCVNCSWCKEVCPVD
TINVTKPFEGTLKLVETDESTCKGDACHACQDVCPCDAVEIIDNKATINLDYCNLCGACVNACPQNIREVTRTSMKLNNI
NSESWRDILTSNLLS

Sequences:

>Translated_335_residues
MFNVERSGEETRKLSHNNDRCVGCGICTDVCPTSSLRLGPIVPIARGLIEMDLVSVTSNTCVLCGLCSVACPFDALSLTI
NGNDIKETGNYPVWEVESEINDDDCIYCGRCYSVCPRDTILFKRELPSREDLVIGEISVDEDKCVYCSICSEMCPAGAIS
LTNNPEFSNDNLNNTIEVDTSKCIYCGVCKRACPQDAIKAVCSTCMLQDQIKAPEINGTASILKDGCVNCSWCKEVCPVD
TINVTKPFEGTLKLVETDESTCKGDACHACQDVCPCDAVEIIDNKATINLDYCNLCGACVNACPQNIREVTRTSMKLNNI
NSESWRDILTSNLLS
>Mature_335_residues
MFNVERSGEETRKLSHNNDRCVGCGICTDVCPTSSLRLGPIVPIARGLIEMDLVSVTSNTCVLCGLCSVACPFDALSLTI
NGNDIKETGNYPVWEVESEINDDDCIYCGRCYSVCPRDTILFKRELPSREDLVIGEISVDEDKCVYCSICSEMCPAGAIS
LTNNPEFSNDNLNNTIEVDTSKCIYCGVCKRACPQDAIKAVCSTCMLQDQIKAPEINGTASILKDGCVNCSWCKEVCPVD
TINVTKPFEGTLKLVETDESTCKGDACHACQDVCPCDAVEIIDNKATINLDYCNLCGACVNACPQNIREVTRTSMKLNNI
NSESWRDILTSNLLS

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR016459 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 36527; Mature: 36527

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

10.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
11.9 %Cys+Met (Translated Protein)
10.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
11.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNVERSGEETRKLSHNNDRCVGCGICTDVCPTSSLRLGPIVPIARGLIEMDLVSVTSNT
CCCCCCCCHHHHHHCCCCCCEEEEECHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
CVLCGLCSVACPFDALSLTINGNDIKETGNYPVWEVESEINDDDCIYCGRCYSVCPRDTI
EEEEEHHHHHCCCCEEEEEECCCCHHHCCCCCEEEECCCCCCCCEEEECCHHCCCCCCCE
LFKRELPSREDLVIGEISVDEDKCVYCSICSEMCPAGAISLTNNPEFSNDNLNNTIEVDT
EEECCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECC
SKCIYCGVCKRACPQDAIKAVCSTCMLQDQIKAPEINGTASILKDGCVNCSWCKEVCPVD
CCEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHCCCCC
TINVTKPFEGTLKLVETDESTCKGDACHACQDVCPCDAVEIIDNKATINLDYCNLCGACV
EEECCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCHHHEECCCEEEEEHHHHHHHHHH
NACPQNIREVTRTSMKLNNINSESWRDILTSNLLS
HHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MFNVERSGEETRKLSHNNDRCVGCGICTDVCPTSSLRLGPIVPIARGLIEMDLVSVTSNT
CCCCCCCCHHHHHHCCCCCCEEEEECHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
CVLCGLCSVACPFDALSLTINGNDIKETGNYPVWEVESEINDDDCIYCGRCYSVCPRDTI
EEEEEHHHHHCCCCEEEEEECCCCHHHCCCCCEEEECCCCCCCCEEEECCHHCCCCCCCE
LFKRELPSREDLVIGEISVDEDKCVYCSICSEMCPAGAISLTNNPEFSNDNLNNTIEVDT
EEECCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECC
SKCIYCGVCKRACPQDAIKAVCSTCMLQDQIKAPEINGTASILKDGCVNCSWCKEVCPVD
CCEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHCCCCC
TINVTKPFEGTLKLVETDESTCKGDACHACQDVCPCDAVEIIDNKATINLDYCNLCGACV
EEECCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCHHHEECCCEEEEEHHHHHHHHHH
NACPQNIREVTRTSMKLNNINSESWRDILTSNLLS
HHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]