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The map label for this gene is ribD [C]

Identifier: 148642125

GI number: 148642125

Start: 63505

End: 64176

Strand: Reverse

Name: ribD [C]

Synonym: Msm_0065

Alternate gene names: 148642125

Gene position: 64176-63505 (Counterclockwise)

Preceding gene: 148642126

Following gene: 148642122

Centisome position: 3.46

GC content: 35.12

Gene sequence:

>672_bases
ATGAAACCGTATGTTATTTTAAATGCAGCTATGACACTGGACGGAAAAATAGCCACTAAAACTGGCAGTTCCAATATTTC
AGGTGAAAAAGATTTGAAAAGAGTTCATGAACTTAGACGTGAAGTTGATGGAATAATGGTTGGGATCAATACGGTTATTG
CAGATAATCCCAGATTAACGGTTCATAAAATAGATGCAAATCCTGAAGACAATCCTGTTCGTGTGGTGGTAGACAGCAAA
TGCAGAACTCCAATAGCTGCACGCATAACAAATAAGGATGCAAAAACCATAATAGCGGGAGCTAATGACTATAAACTTGA
ATTTATTGTAAGTGACAGATATGCCAATTTTACTAAAAGGGGAATTGACTTCTTTTTCAGCGGGGATAAAAGAGTTGACC
TAAAAGATTTAATGAATTATCTTTATGAAAGCGGTATTAAAACACTGATGCTTGAGGGTGGTTCAACTCTAAACTTTTCA
ATGATTAAAGAGGGTTTAATTGATGAAATAAGAATTTGTGTCGCTCCTTTTGTTGTTGGGGGTAAGGATTCACATACATT
ATTTGACGGTGAAGGATTTGACACAATGGATGAAGGGGTAAGACTGGAGCTTTTTGATTCATTTAAATTAGGTGATGACT
TAATATTGCAGTATAAAGTTTTGAATAAGTGA

Upstream 100 bases:

>100_bases
GTATAATTGTTGCAATAGTAATGCCTGATGTGCTTCAAAACCAGACATTGGCTAATTTCATGCAGATTAAGGAATTCTTT
TATCAGTTAGGATGATTTGA

Downstream 100 bases:

>100_bases
TTTTTTTCACTTATGCTATTTTTTTAAAACATAAATGCAAATGGCGGATTTTTGCAAATGCAATATCTGCAGAGAGATTT
CTGGTCTTTTATAAATTTTG

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKPYVILNAAMTLDGKIATKTGSSNISGEKDLKRVHELRREVDGIMVGINTVIADNPRLTVHKIDANPEDNPVRVVVDSK
CRTPIAARITNKDAKTIIAGANDYKLEFIVSDRYANFTKRGIDFFFSGDKRVDLKDLMNYLYESGIKTLMLEGGSTLNFS
MIKEGLIDEIRICVAPFVVGGKDSHTLFDGEGFDTMDEGVRLELFDSFKLGDDLILQYKVLNK

Sequences:

>Translated_223_residues
MKPYVILNAAMTLDGKIATKTGSSNISGEKDLKRVHELRREVDGIMVGINTVIADNPRLTVHKIDANPEDNPVRVVVDSK
CRTPIAARITNKDAKTIIAGANDYKLEFIVSDRYANFTKRGIDFFFSGDKRVDLKDLMNYLYESGIKTLMLEGGSTLNFS
MIKEGLIDEIRICVAPFVVGGKDSHTLFDGEGFDTMDEGVRLELFDSFKLGDDLILQYKVLNK
>Mature_223_residues
MKPYVILNAAMTLDGKIATKTGSSNISGEKDLKRVHELRREVDGIMVGINTVIADNPRLTVHKIDANPEDNPVRVVVDSK
CRTPIAARITNKDAKTIIAGANDYKLEFIVSDRYANFTKRGIDFFFSGDKRVDLKDLMNYLYESGIKTLMLEGGSTLNFS
MIKEGLIDEIRICVAPFVVGGKDSHTLFDGEGFDTMDEGVRLELFDSFKLGDDLILQYKVLNK

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=226, Percent_Identity=26.1061946902655, Blast_Score=80, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 24874; Mature: 24874

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPYVILNAAMTLDGKIATKTGSSNISGEKDLKRVHELRREVDGIMVGINTVIADNPRLT
CCCEEEEEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEEEECCCEEE
VHKIDANPEDNPVRVVVDSKCRTPIAARITNKDAKTIIAGANDYKLEFIVSDRYANFTKR
EEEECCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCCEEEEEEEECCCCCHHHH
GIDFFFSGDKRVDLKDLMNYLYESGIKTLMLEGGSTLNFSMIKEGLIDEIRICVAPFVVG
CCEEEECCCCEECHHHHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHEEEC
GKDSHTLFDGEGFDTMDEGVRLELFDSFKLGDDLILQYKVLNK
CCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure
MKPYVILNAAMTLDGKIATKTGSSNISGEKDLKRVHELRREVDGIMVGINTVIADNPRLT
CCCEEEEEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEEEECCCEEE
VHKIDANPEDNPVRVVVDSKCRTPIAARITNKDAKTIIAGANDYKLEFIVSDRYANFTKR
EEEECCCCCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCCEEEEEEEECCCCCHHHH
GIDFFFSGDKRVDLKDLMNYLYESGIKTLMLEGGSTLNFSMIKEGLIDEIRICVAPFVVG
CCEEEECCCCEECHHHHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHEEEC
GKDSHTLFDGEGFDTMDEGVRLELFDSFKLGDDLILQYKVLNK
CCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]