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The map label for this gene is lpxA [H]

Identifier: 148381057

GI number: 148381057

Start: 3295785

End: 3296531

Strand: Reverse

Name: lpxA [H]

Synonym: CBO3106

Alternate gene names: 148381057

Gene position: 3296531-3295785 (Counterclockwise)

Preceding gene: 148381058

Following gene: 148381056

Centisome position: 84.81

GC content: 30.92

Gene sequence:

>747_bases
ATGAAAATGAATTATATATCCTCAAAGTCTAAATTAGGCAATAATGTTGAAGTAGGGAAATTTGCTGTTATAGAAGATGA
TGTAGTTATAGGAGAAAATTGTATTATAGGGCACAATGTAATTATACATAAAGGAACAATCATAGGTAACAATGTAAGAA
TAGATGATAACACTGTAATAGGAAAAGAGCCCATGAGATCAGTAAACAGTATATTTAAAGATGATAAAGAGTTTGAACCA
TGTAAAATTAATGATGAATGTTTAATAGGAGCAGGTGTAATAGTATATATAGGTTCTAAAATAGGTAATAAAACTTTAGT
AGCTGACCTAGCTGTTATAAGAGAAGACGTAACTATAGGAGAAAGAACAATAATAGGCAAAGGTGCAACTATAGAAAACT
TTTGCAAAGTGGGCTCAAATTGTAAAATTCAGACTAATGTATATTTAACAGCATATTCAGAAGTAGAGGATTATGTTTTC
ATAGCACCTTGTGTAGTAACATCTAATGATAACTATGCTGCTCGATCAAAAGAAAGATTTGGTAAATTTAAAGGTGTTAC
AATTAAAAAAGGTGGAAGAATAGGGGCAGGTGCAGTTATATTGCCAGGAAAAATAATACATGAAGATGGATTTGCAGCAG
CAGGAAGTTTAGTAACTAGGGATATAGAAAAAGCTAAGATAGTTGCAGGAGTACCAGCTAAAATATTTAATGATGTACCA
AAAGAACAGTTGTTAGAAAATCAATAG

Upstream 100 bases:

>100_bases
ATTTATTAAATAAAAATTAAATTTTTAAAATTACCATCAAAATATGATATTATATTATGGTGGTAATTTTAAAATTTTAT
TTTAATATAGGAGTGAAAAC

Downstream 100 bases:

>100_bases
CTAAAAATATGGATTAAAGGGTGTTTTAAGTTGAGTTATAAGAGGAATATTGCAAGTAATTTTTTAACACAAATAATAGC
ATCAGCTATAGGCTTTTTTA

Product: putative acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKMNYISSKSKLGNNVEVGKFAVIEDDVVIGENCIIGHNVIIHKGTIIGNNVRIDDNTVIGKEPMRSVNSIFKDDKEFEP
CKINDECLIGAGVIVYIGSKIGNKTLVADLAVIREDVTIGERTIIGKGATIENFCKVGSNCKIQTNVYLTAYSEVEDYVF
IAPCVVTSNDNYAARSKERFGKFKGVTIKKGGRIGAGAVILPGKIIHEDGFAAAGSLVTRDIEKAKIVAGVPAKIFNDVP
KEQLLENQ

Sequences:

>Translated_248_residues
MKMNYISSKSKLGNNVEVGKFAVIEDDVVIGENCIIGHNVIIHKGTIIGNNVRIDDNTVIGKEPMRSVNSIFKDDKEFEP
CKINDECLIGAGVIVYIGSKIGNKTLVADLAVIREDVTIGERTIIGKGATIENFCKVGSNCKIQTNVYLTAYSEVEDYVF
IAPCVVTSNDNYAARSKERFGKFKGVTIKKGGRIGAGAVILPGKIIHEDGFAAAGSLVTRDIEKAKIVAGVPAKIFNDVP
KEQLLENQ
>Mature_248_residues
MKMNYISSKSKLGNNVEVGKFAVIEDDVVIGENCIIGHNVIIHKGTIIGNNVRIDDNTVIGKEPMRSVNSIFKDDKEFEP
CKINDECLIGAGVIVYIGSKIGNKTLVADLAVIREDVTIGERTIIGKGATIENFCKVGSNCKIQTNVYLTAYSEVEDYVF
IAPCVVTSNDNYAARSKERFGKFKGVTIKKGGRIGAGAVILPGKIIHEDGFAAAGSLVTRDIEKAKIVAGVPAKIFNDVP
KEQLLENQ

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 26820; Mature: 26820

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNYISSKSKLGNNVEVGKFAVIEDDVVIGENCIIGHNVIIHKGTIIGNNVRIDDNTVI
CCCCCCCCHHHCCCCCCCCEEEEEECCEEECCCEEEECEEEEEECEEECCEEEECCCEEE
GKEPMRSVNSIFKDDKEFEPCKINDECLIGAGVIVYIGSKIGNKTLVADLAVIREDVTIG
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHCCCCC
ERTIIGKGATIENFCKVGSNCKIQTNVYLTAYSEVEDYVFIAPCVVTSNDNYAARSKERF
CEEEEECCCCHHHHHHCCCCCEEEEEEEEEEECCCCCEEEEEEEEEECCCCCCHHCHHHH
GKFKGVTIKKGGRIGAGAVILPGKIIHEDGFAAAGSLVTRDIEKAKIVAGVPAKIFNDVP
CCCCCEEEECCCCCCCCEEEECCEEEECCCCCHHCHHHHHHHHHHEEEECCCHHHHHCCC
KEQLLENQ
HHHHHCCC
>Mature Secondary Structure
MKMNYISSKSKLGNNVEVGKFAVIEDDVVIGENCIIGHNVIIHKGTIIGNNVRIDDNTVI
CCCCCCCCHHHCCCCCCCCEEEEEECCEEECCCEEEECEEEEEECEEECCEEEECCCEEE
GKEPMRSVNSIFKDDKEFEPCKINDECLIGAGVIVYIGSKIGNKTLVADLAVIREDVTIG
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHCCCCC
ERTIIGKGATIENFCKVGSNCKIQTNVYLTAYSEVEDYVFIAPCVVTSNDNYAARSKERF
CEEEEECCCCHHHHHHCCCCCEEEEEEEEEEECCCCCEEEEEEEEEECCCCCCHHCHHHH
GKFKGVTIKKGGRIGAGAVILPGKIIHEDGFAAAGSLVTRDIEKAKIVAGVPAKIFNDVP
CCCCCEEEECCCCCCCCEEEECCEEEECCCCCHHCHHHHHHHHHHEEEECCCHHHHHCCC
KEQLLENQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]