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The map label for this gene is cssR [H]

Identifier: 148378297

GI number: 148378297

Start: 347264

End: 347941

Strand: Direct

Name: cssR [H]

Synonym: CBO0295

Alternate gene names: 148378297

Gene position: 347264-347941 (Clockwise)

Preceding gene: 148378296

Following gene: 148378298

Centisome position: 8.93

GC content: 28.02

Gene sequence:

>678_bases
ATGGGAAGAAAAGTCTATCTTGTTGAAGATGAAAAAAGTCTGAATATATTATTAGAAAAGTATCTACAACGTGAAGGGTA
TGAAGTAACTACTTTTTTTAATGGAAGTTCTGCAATAGAAAGAATAAAAGATGTTCCAGATATTTGGATATTAGATATAA
TGTTACCTGATATAGATGGATATCAAATAATTAAAGCTGTAAAAGAAAACAATAAAAATACTCCAGTTATCTTTATGTCT
GCGAGGAATGAGGAACTGGATAGAGTAGTGGGATTAGAATTAGGAAGTGATGATTATTTATCAAAGCCATTCTTACCTAG
AGAGCTTATAATAAGAACTAATAAGCTTATGGAAAGAATTTATGGGAAAAGTAATAATAGTACTGTAGATATAATTACAA
ATATTGGGCAGTACAAAATAAGTAAAAAGCAAAGAACTGTTTTTTTCGAAGAAAAAGAAATTCAACTAACAAATAAAGAG
TTTGAACTATTAAATTTTTTTATAGAGAATAAAAACAATGTTATATCTAGAGAGCAAATTTTAATTAGTATTTGGGGAGA
GGATTATTTCGGATCCGATAGAGTTATTGATGATACAATTAGGAGATTGCGCAAAAAGATGGATAAGTTAGATCTTGAAA
CTGTATATGGATATGGTTATAAATTGGTGGTTAAATGA

Upstream 100 bases:

>100_bases
TTACTAATGTCATAGATGTAAAGTAAATGGTGACTGTAAAATTAAAAATAAGGTTTAATGGATAAACTAAAATACTGGAT
TATATTTTGGGGTGATAAAT

Downstream 100 bases:

>100_bases
TGAAGAGATTAAGATTTAAATCATTAACAATGAGGATATGGACAACATTCACTGCTATAATTTTAATAATAATATGTAGT
ATTTCATTTTTATATTTAGT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDGYQIIKAVKENNKNTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKE
FELLNFFIENKNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Sequences:

>Translated_225_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDGYQIIKAVKENNKNTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKE
FELLNFFIENKNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
>Mature_224_residues
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDGYQIIKAVKENNKNTPVIFMSA
RNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKEF
ELLNFFIENKNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=36.1607142857143, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=34.3347639484979, Blast_Score=143, Evalue=7e-36,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.8777292576419, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=32.0175438596491, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.6491228070175, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.8947368421053, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.7826086956522, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.920704845815, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=30.4545454545455, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=30.7017543859649, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.0429184549356, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=30.1801801801802, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=27.9279279279279, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=211, Percent_Identity=29.3838862559242, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=35.6435643564356, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26470; Mature: 26339

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDG
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKNTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKEFELLNFFIENKNNVISREQI
HCCCCCCEEEEEECCCCEEECCCCEEEEEECCEEEECCHHHHHHHHHHHCCCCEECCEEE
LISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCEEEEEC
>Mature Secondary Structure 
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDG
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKNTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSTVDIITNIGQYKISKKQRTVFFEEKEIQLTNKEFELLNFFIENKNNVISREQI
HCCCCCCEEEEEECCCCEEECCCCEEEEEECCEEEECCHHHHHHHHHHHCCCCEECCEEE
LISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]