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The map label for this gene is ade [H]

Identifier: 148378296

GI number: 148378296

Start: 345062

End: 346861

Strand: Direct

Name: ade [H]

Synonym: CBO0294

Alternate gene names: 148378296

Gene position: 345062-346861 (Clockwise)

Preceding gene: 148378295

Following gene: 148378297

Centisome position: 8.88

GC content: 34.5

Gene sequence:

>1800_bases
ATGTTTAATAAATTTGATACAAAGCCTCTTTGGGAGGTAAGTAAAACTTTATCAAGTGTAGCACAGGGGCTTGAACCGGC
TGATATGGTTATTATAAATTCAAGGCTTATAAATGTCTGTACAAGAGAAGTCATAGAAAACACAGATGTAGCAATTAGCT
GTGGAAGAATTGCTTTAGTAGGTGATGCAAAACATTGCATAGGGGAAAACACAGAGGTAATTGATGCAAAAGGACAATAT
ATTGCACCAGGTTTTTTAGATGGTCATATTCATGTTGAATCATCAATGTTAAGTGTAAGCGAATATGCTCGTTCAGTAGT
TCCACATGGTACTGTCGGAATATATATGGATCCACATGAAATTTGTAATGTACTCGGATTAAATGGTGTACGTTATATGA
TTGAAGATGGCAAGGGTACTCCACTTAAAAATATGGTGACCACACCATCCTGTGTACCAGCAGTTCCAGGTTTTGAAGAT
ACAGGAGCGGCTGTAGGACCAGAAGATGTTAGAGAAACAATGAAGTGGGATGAAATAGTTGGATTAGGAGAAATGATGAA
CTTCCCAGGTATACTTTATTCTACAGATCATGCTCATGGAGTAGTAGGAGAAACTTTAAAAGCTAGTAAAACAGTAACAG
GACATTATTCTTTACCTGAAACAGGAAAAGGATTAAATGGATATATTGCATCAGGTGTAAGATGTTGTCATGAATCCACA
AGAGCGGAAGATGCTCTTGCTAAAATGCGCCTTGGAATGTATGCAATGTTTAGAGAAGGATCTGCATGGCATGACTTAAA
GGAAGTAAGTAAAGCCATTACAGAAAATAAGGTAGATAGTAGATTTGCTGTTTTAATATCTGATGATACTCACCCACACA
CATTGCTTAAGGATGGACATTTAGATCATATTATAAAACGTGCTATAGAAGAAGGGATAGAGCCATTAACTGCAATTCAA
ATGGTAACAATAAATTGTGCACAATGTTTCCAAATGGATCATGAATTAGGTTCTATAACTCCAGGAAAATGTGCAGATAT
TGTATTTATAGAAGATTTAAAAGATGTAAAAATAACAAAGGTTATTATAGATGGAAATTTAGTTGCAAAGGGTGGACTAT
TAACTACTTCAATAGCTAAATATGATTATCCTGAAGATGCTATGAATTCAATGCATATTAAGAATAAAATAACACCAGAT
TCCTTTAATATTATGGCTCCTAATAAAGAAAAAATAACTGCAAGGGTTATTGAAATTATACCTGAAAGAGTTGGTACATA
TGAGAGACATGTTGAACTTAATGTTAAAGATGATAAAGTTCAATGTGATCCAAGTAAAGATGTTTTAAAAGCAGTTGTAT
TTGAAAGACACCATGAAACAGGAACAGCAGGATATGGTTTTGTTAAAGGTTTTGGTATTAAGAGAGGAGCTATGGCTGCA
ACAGTTGCCCATGATGCTCACAACTTATTAGTTATAGGAACAAATGATGAAGATATGGCATTAGCTGCTAATACATTAAT
AGAATGTGGTGGAGGAATGGTAGCCGTACAAGATGGTAAAGTATTAGGCTTAGTTCCATTACCAATAGCAGGACTTATGA
GTAATAAGCCTTTAGAAGAAATGGCAGAAATGGTAGAAAAACTAGATAGTGCATGGAAAGAAATAGGATGTGATATAGTT
TCACCATTTATGACAATAGCACTTATTCCACTTGCCTGCCTACCAGAATTAAGACTAACTAATAGAGGGTTAGTTGATTG
TAATAAGTTTGAATTTGTATCATTATTTGTAGAAGAATAA

Upstream 100 bases:

>100_bases
AAACGATAGATAAATAATGTGGAATATATTATAAAAATATAATATAATGTATAAAAATATACAAAGAGAAATCTATAAAA
ATACAAAAGGAGACGGGGAT

Downstream 100 bases:

>100_bases
ATATAGAGAAACGTATTTAAAGTTTATAATTATTTTTGATTATTAAGAGAGTTATCGCATAAATTGTAAAAATTTTAATG
TGGTGATTCTCTTTTTATAC

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MFNKFDTKPLWEVSKTLSSVAQGLEPADMVIINSRLINVCTREVIENTDVAISCGRIALVGDAKHCIGENTEVIDAKGQY
IAPGFLDGHIHVESSMLSVSEYARSVVPHGTVGIYMDPHEICNVLGLNGVRYMIEDGKGTPLKNMVTTPSCVPAVPGFED
TGAAVGPEDVRETMKWDEIVGLGEMMNFPGILYSTDHAHGVVGETLKASKTVTGHYSLPETGKGLNGYIASGVRCCHEST
RAEDALAKMRLGMYAMFREGSAWHDLKEVSKAITENKVDSRFAVLISDDTHPHTLLKDGHLDHIIKRAIEEGIEPLTAIQ
MVTINCAQCFQMDHELGSITPGKCADIVFIEDLKDVKITKVIIDGNLVAKGGLLTTSIAKYDYPEDAMNSMHIKNKITPD
SFNIMAPNKEKITARVIEIIPERVGTYERHVELNVKDDKVQCDPSKDVLKAVVFERHHETGTAGYGFVKGFGIKRGAMAA
TVAHDAHNLLVIGTNDEDMALAANTLIECGGGMVAVQDGKVLGLVPLPIAGLMSNKPLEEMAEMVEKLDSAWKEIGCDIV
SPFMTIALIPLACLPELRLTNRGLVDCNKFEFVSLFVEE

Sequences:

>Translated_599_residues
MFNKFDTKPLWEVSKTLSSVAQGLEPADMVIINSRLINVCTREVIENTDVAISCGRIALVGDAKHCIGENTEVIDAKGQY
IAPGFLDGHIHVESSMLSVSEYARSVVPHGTVGIYMDPHEICNVLGLNGVRYMIEDGKGTPLKNMVTTPSCVPAVPGFED
TGAAVGPEDVRETMKWDEIVGLGEMMNFPGILYSTDHAHGVVGETLKASKTVTGHYSLPETGKGLNGYIASGVRCCHEST
RAEDALAKMRLGMYAMFREGSAWHDLKEVSKAITENKVDSRFAVLISDDTHPHTLLKDGHLDHIIKRAIEEGIEPLTAIQ
MVTINCAQCFQMDHELGSITPGKCADIVFIEDLKDVKITKVIIDGNLVAKGGLLTTSIAKYDYPEDAMNSMHIKNKITPD
SFNIMAPNKEKITARVIEIIPERVGTYERHVELNVKDDKVQCDPSKDVLKAVVFERHHETGTAGYGFVKGFGIKRGAMAA
TVAHDAHNLLVIGTNDEDMALAANTLIECGGGMVAVQDGKVLGLVPLPIAGLMSNKPLEEMAEMVEKLDSAWKEIGCDIV
SPFMTIALIPLACLPELRLTNRGLVDCNKFEFVSLFVEE
>Mature_599_residues
MFNKFDTKPLWEVSKTLSSVAQGLEPADMVIINSRLINVCTREVIENTDVAISCGRIALVGDAKHCIGENTEVIDAKGQY
IAPGFLDGHIHVESSMLSVSEYARSVVPHGTVGIYMDPHEICNVLGLNGVRYMIEDGKGTPLKNMVTTPSCVPAVPGFED
TGAAVGPEDVRETMKWDEIVGLGEMMNFPGILYSTDHAHGVVGETLKASKTVTGHYSLPETGKGLNGYIASGVRCCHEST
RAEDALAKMRLGMYAMFREGSAWHDLKEVSKAITENKVDSRFAVLISDDTHPHTLLKDGHLDHIIKRAIEEGIEPLTAIQ
MVTINCAQCFQMDHELGSITPGKCADIVFIEDLKDVKITKVIIDGNLVAKGGLLTTSIAKYDYPEDAMNSMHIKNKITPD
SFNIMAPNKEKITARVIEIIPERVGTYERHVELNVKDDKVQCDPSKDVLKAVVFERHHETGTAGYGFVKGFGIKRGAMAA
TVAHDAHNLLVIGTNDEDMALAANTLIECGGGMVAVQDGKVLGLVPLPIAGLMSNKPLEEMAEMVEKLDSAWKEIGCDIV
SPFMTIALIPLACLPELRLTNRGLVDCNKFEFVSLFVEE

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=590, Percent_Identity=32.8813559322034, Blast_Score=302, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 65233; Mature: 65233

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKFDTKPLWEVSKTLSSVAQGLEPADMVIINSRLINVCTREVIENTDVAISCGRIALV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCEEEEE
GDAKHCIGENTEVIDAKGQYIAPGFLDGHIHVESSMLSVSEYARSVVPHGTVGIYMDPHE
CCCHHHCCCCCEEEECCCCEECCCEECCEEEEHHHHHHHHHHHHHHCCCCCEEEEECHHH
ICNVLGLNGVRYMIEDGKGTPLKNMVTTPSCVPAVPGFEDTGAAVGPEDVRETMKWDEIV
HHHHHCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GLGEMMNFPGILYSTDHAHGVVGETLKASKTVTGHYSLPETGKGLNGYIASGVRCCHEST
CHHHHHCCCCEEEECCCCCCCCCCHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
RAEDALAKMRLGMYAMFREGSAWHDLKEVSKAITENKVDSRFAVLISDDTHPHTLLKDGH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCC
LDHIIKRAIEEGIEPLTAIQMVTINCAQCFQMDHELGSITPGKCADIVFIEDLKDVKITK
HHHHHHHHHHHCCCHHHHHHHEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEE
VIIDGNLVAKGGLLTTSIAKYDYPEDAMNSMHIKNKITPDSFNIMAPNKEKITARVIEII
EEEECCEEECCCEEEEHHHHCCCCHHHHHCEECCCCCCCCCEEEECCCHHHHHHHHHHHH
PERVGTYERHVELNVKDDKVQCDPSKDVLKAVVFERHHETGTAGYGFVKGFGIKRGAMAA
HHHHCCEEEEEEEEEECCCEECCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCE
TVAHDAHNLLVIGTNDEDMALAANTLIECGGGMVAVQDGKVLGLVPLPIAGLMSNKPLEE
EEEECCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHCCCCHHH
MAEMVEKLDSAWKEIGCDIVSPFMTIALIPLACLPELRLTNRGLVDCNKFEFVSLFVEE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MFNKFDTKPLWEVSKTLSSVAQGLEPADMVIINSRLINVCTREVIENTDVAISCGRIALV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCEEEEE
GDAKHCIGENTEVIDAKGQYIAPGFLDGHIHVESSMLSVSEYARSVVPHGTVGIYMDPHE
CCCHHHCCCCCEEEECCCCEECCCEECCEEEEHHHHHHHHHHHHHHCCCCCEEEEECHHH
ICNVLGLNGVRYMIEDGKGTPLKNMVTTPSCVPAVPGFEDTGAAVGPEDVRETMKWDEIV
HHHHHCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GLGEMMNFPGILYSTDHAHGVVGETLKASKTVTGHYSLPETGKGLNGYIASGVRCCHEST
CHHHHHCCCCEEEECCCCCCCCCCHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
RAEDALAKMRLGMYAMFREGSAWHDLKEVSKAITENKVDSRFAVLISDDTHPHTLLKDGH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCC
LDHIIKRAIEEGIEPLTAIQMVTINCAQCFQMDHELGSITPGKCADIVFIEDLKDVKITK
HHHHHHHHHHHCCCHHHHHHHEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEE
VIIDGNLVAKGGLLTTSIAKYDYPEDAMNSMHIKNKITPDSFNIMAPNKEKITARVIEII
EEEECCEEECCCEEEEHHHHCCCCHHHHHCEECCCCCCCCCEEEECCCHHHHHHHHHHHH
PERVGTYERHVELNVKDDKVQCDPSKDVLKAVVFERHHETGTAGYGFVKGFGIKRGAMAA
HHHHCCEEEEEEEEEECCCEECCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCE
TVAHDAHNLLVIGTNDEDMALAANTLIECGGGMVAVQDGKVLGLVPLPIAGLMSNKPLEE
EEEECCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHCCCCHHH
MAEMVEKLDSAWKEIGCDIVSPFMTIALIPLACLPELRLTNRGLVDCNKFEFVSLFVEE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA