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The map label for this gene is nuoD

Identifier: 148361099

GI number: 148361099

Start: 3316370

End: 3317623

Strand: Reverse

Name: nuoD

Synonym: LPC_3072

Alternate gene names: 148361099

Gene position: 3317623-3316370 (Counterclockwise)

Preceding gene: 148361100

Following gene: 148361098

Centisome position: 92.76

GC content: 41.47

Gene sequence:

>1254_bases
ATGATTGAACTTAAAAATTATACCTTGAATTTTGGCCCGCAACATCCTGCTGCACATGGTGTTTTAAGATTGGTTCTTGA
GTTAGAGGGTGAAACTATCGTTCGTGCTGATCCACATATTGGATTGCTTCATCGTGCAACAGAAAAATTGGCTGAGACCA
AGCCTTACATTCAAAGCATTGGTTACATGGACAGATTAGATTACGTCTCAATGATGTGTAACGAACATGCTTATGTCATG
GCGATTGAGAAGTTATTGGGTATAGAACCACCTTTGCGAGCCAAGTACATACGAACTATGTTTGATGAGGTGACTCGAAT
TCTGAACCATCTCTTGTGGTTAGGAGCTACTGCATTGGATATTGGTGCAATGACTGTGTTTCTTTATTGCTTCAGAGAGC
GAGAAGATTTGTTTGATTGCTACGAGGCAGTTTCAGGAGCACGTATGCATGCTACCTACTACAGACCAGGAGGGGTAGCA
AGGGATTTGCCAGATACTATGCCTCAATACAAACCGTCAAGATGGCATAACGAAAGAGAGATTGAAAAAAAGAATCACAA
TCGTCAGGGTAGCCTTTTGGATTTTCTTTGGGCCTTTACTGAGCGATTTCCCCGCTGTGTGGATGAATACGAAACATTGT
TAACCGATAATCGTATATGGAAACAACGTACTGTAGATATTGGTATCGTTTCACCTGAAAATGCGCTGCAATGGGGGTTT
ACCGGACCAATGTTAAGAGGCTCCGGTATTGCCTGGGATTTACGCAAGAAACAGAGCTATGCTGCTTACGATAGGGTTGA
TTTTGATATTCCCGTTGGCAAGACAGGGGATTGTTATGATCGATATTTGGTAAGAGTCGAGGAATTAAGACAATCCAATC
GAATTATAAGACAATGTATTGAGTGGTTGCGCAAGCATCCTGGTCCAGTAAAAGTCGATGATTATAAAGTGACGCCTCCA
CGCCGTGTAGTAATGAAACATGACATGGAAGCATTAATTCATCACTTTAAATTATTTACCGAAGGCTTTTGTTTACCGCG
AGGTGAAGTTTATTCATCTGTTGAAGCGCCAAAGGGCGAGTTTGGGATCTATATGGTGTCAGATGGAGCTAATAAACCTT
ACCGTCTGAAAATAAGAGCTCCAGGATTTGCTCATTTATCAAGCTTTGATGATATGGTTAGAGGTCACATGCTAGCTGAT
GGAGTGGCTATATTGGCAAGTCAAGATATAGTGTTTGGAGAGATTGATCGTTAA

Upstream 100 bases:

>100_bases
CAAAAGGTAATATATGCCCCTGTAGACATTGTGCCAAGAATTGTAGTTCCAAAAGTTATTCGTAATGATAACCGCTACAT
AGGTAATGAAGGTAGCAAAA

Downstream 100 bases:

>100_bases
TTTAACGACATGCTTGCTTAAAGTGTATTAAAGAGATAATAAACGATATAAAGGTTTCGAAATGTCTGCTAATTCAGCAA
AAATATTAAATCAATTGATG

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MIELKNYTLNFGPQHPAAHGVLRLVLELEGETIVRADPHIGLLHRATEKLAETKPYIQSIGYMDRLDYVSMMCNEHAYVM
AIEKLLGIEPPLRAKYIRTMFDEVTRILNHLLWLGATALDIGAMTVFLYCFREREDLFDCYEAVSGARMHATYYRPGGVA
RDLPDTMPQYKPSRWHNEREIEKKNHNRQGSLLDFLWAFTERFPRCVDEYETLLTDNRIWKQRTVDIGIVSPENALQWGF
TGPMLRGSGIAWDLRKKQSYAAYDRVDFDIPVGKTGDCYDRYLVRVEELRQSNRIIRQCIEWLRKHPGPVKVDDYKVTPP
RRVVMKHDMEALIHHFKLFTEGFCLPRGEVYSSVEAPKGEFGIYMVSDGANKPYRLKIRAPGFAHLSSFDDMVRGHMLAD
GVAILASQDIVFGEIDR

Sequences:

>Translated_417_residues
MIELKNYTLNFGPQHPAAHGVLRLVLELEGETIVRADPHIGLLHRATEKLAETKPYIQSIGYMDRLDYVSMMCNEHAYVM
AIEKLLGIEPPLRAKYIRTMFDEVTRILNHLLWLGATALDIGAMTVFLYCFREREDLFDCYEAVSGARMHATYYRPGGVA
RDLPDTMPQYKPSRWHNEREIEKKNHNRQGSLLDFLWAFTERFPRCVDEYETLLTDNRIWKQRTVDIGIVSPENALQWGF
TGPMLRGSGIAWDLRKKQSYAAYDRVDFDIPVGKTGDCYDRYLVRVEELRQSNRIIRQCIEWLRKHPGPVKVDDYKVTPP
RRVVMKHDMEALIHHFKLFTEGFCLPRGEVYSSVEAPKGEFGIYMVSDGANKPYRLKIRAPGFAHLSSFDDMVRGHMLAD
GVAILASQDIVFGEIDR
>Mature_417_residues
MIELKNYTLNFGPQHPAAHGVLRLVLELEGETIVRADPHIGLLHRATEKLAETKPYIQSIGYMDRLDYVSMMCNEHAYVM
AIEKLLGIEPPLRAKYIRTMFDEVTRILNHLLWLGATALDIGAMTVFLYCFREREDLFDCYEAVSGARMHATYYRPGGVA
RDLPDTMPQYKPSRWHNEREIEKKNHNRQGSLLDFLWAFTERFPRCVDEYETLLTDNRIWKQRTVDIGIVSPENALQWGF
TGPMLRGSGIAWDLRKKQSYAAYDRVDFDIPVGKTGDCYDRYLVRVEELRQSNRIIRQCIEWLRKHPGPVKVDDYKVTPP
RRVVMKHDMEALIHHFKLFTEGFCLPRGEVYSSVEAPKGEFGIYMVSDGANKPYRLKIRAPGFAHLSSFDDMVRGHMLAD
GVAILASQDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=59.9033816425121, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=59.0686274509804, Blast_Score=493, Evalue=1e-139,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=38.780487804878, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1789076, Length=415, Percent_Identity=28.6746987951807, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788832, Length=408, Percent_Identity=27.2058823529412, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17568379, Length=415, Percent_Identity=57.8313253012048, Blast_Score=489, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17555284, Length=415, Percent_Identity=58.3132530120482, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24638644, Length=415, Percent_Identity=59.2771084337349, Blast_Score=513, Evalue=1e-145,
Organism=Drosophila melanogaster, GI221459469, Length=409, Percent_Identity=54.0342298288509, Blast_Score=454, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_LEGPA (Q5X1B0)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125138.1
- HSSP:   Q56220
- ProteinModelPortal:   Q5X1B0
- SMR:   Q5X1B0
- STRING:   Q5X1B0
- GeneID:   3119469
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2833
- LegioList:   lpp2833
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   MADVITI
- ProtClustDB:   PRK06075
- BioCyc:   LPNE297246:LPP2833-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 48194; Mature: 48194

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELKNYTLNFGPQHPAAHGVLRLVLELEGETIVRADPHIGLLHRATEKLAETKPYIQSI
CEEEECCEEECCCCCCHHHHHHHHHHEECCCEEEECCCCCHHHHHHHHHHHHCCHHHHHC
GYMDRLDYVSMMCNEHAYVMAIEKLLGIEPPLRAKYIRTMFDEVTRILNHLLWLGATALD
CHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAMTVFLYCFREREDLFDCYEAVSGARMHATYYRPGGVARDLPDTMPQYKPSRWHNERE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCHHH
IEKKNHNRQGSLLDFLWAFTERFPRCVDEYETLLTDNRIWKQRTVDIGIVSPENALQWGF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCCCEECCC
TGPMLRGSGIAWDLRKKQSYAAYDRVDFDIPVGKTGDCYDRYLVRVEELRQSNRIIRQCI
CCCCCCCCCCEEEHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKHPGPVKVDDYKVTPPRRVVMKHDMEALIHHFKLFTEGFCLPRGEVYSSVEAPKGE
HHHHCCCCCCEECCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC
FGIYMVSDGANKPYRLKIRAPGFAHLSSFDDMVRGHMLADGVAILASQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCCC
>Mature Secondary Structure
MIELKNYTLNFGPQHPAAHGVLRLVLELEGETIVRADPHIGLLHRATEKLAETKPYIQSI
CEEEECCEEECCCCCCHHHHHHHHHHEECCCEEEECCCCCHHHHHHHHHHHHCCHHHHHC
GYMDRLDYVSMMCNEHAYVMAIEKLLGIEPPLRAKYIRTMFDEVTRILNHLLWLGATALD
CHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAMTVFLYCFREREDLFDCYEAVSGARMHATYYRPGGVARDLPDTMPQYKPSRWHNERE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCHHH
IEKKNHNRQGSLLDFLWAFTERFPRCVDEYETLLTDNRIWKQRTVDIGIVSPENALQWGF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCCCEECCC
TGPMLRGSGIAWDLRKKQSYAAYDRVDFDIPVGKTGDCYDRYLVRVEELRQSNRIIRQCI
CCCCCCCCCCEEEHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKHPGPVKVDDYKVTPPRRVVMKHDMEALIHHFKLFTEGFCLPRGEVYSSVEAPKGE
HHHHCCCCCCEECCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC
FGIYMVSDGANKPYRLKIRAPGFAHLSSFDDMVRGHMLADGVAILASQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA