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The map label for this gene is nuoC [H]

Identifier: 148361100

GI number: 148361100

Start: 3317616

End: 3318299

Strand: Reverse

Name: nuoC [H]

Synonym: LPC_3073

Alternate gene names: 148361100

Gene position: 3318299-3317616 (Counterclockwise)

Preceding gene: 148361101

Following gene: 148361099

Centisome position: 92.78

GC content: 36.99

Gene sequence:

>684_bases
ATGACAAAAAATGAGTATTTGATTGAAAAGCTACAAGCTGATTTAGCAAATCATATCACCGAGTTGACCTCCGCATATGG
TGAAGTAACTATTGAGTGTGAGGTGCAAAATTTATTGCCTGTTATGATTGAGTTGAGAGACAGAGAGGAATTTTCTTTCG
ATCAGTTAATTGATCTATGTGGCGTAGATTATTTGCATTATGGTGATTATGATTGGGAAACAGAGTCTGCGACAGAGCAT
GGATTTTCACGAGGTGTTGAACGCCAAGAAGCTAAGGCTTATGCTGTTAATAAACCACGATTCGCCGTAGTCTATCATTT
ATTATCAACCCAAAAGAATCATCGTTTACGAGTCAAATTATTTGTAGAAGAATCTCATTTAATTGTTCCATCAGTACATC
ATTTATGGAAGTCTGCTAACTGGTTTGAACGAGAAGCTTATGATTTATATGGGATTTTATTTGATGGTCATCCTGATTTA
AGACGGTTACTGACGGATTATGGTTTTATAGGCCACCCTTTCCGCAAGGATTTTCCACTCAGTGGAGAGGTGGAAATGAG
ATATGATGCAAAACTGCAAAAGGTAATATATGCCCCTGTAGACATTGTGCCAAGAATTGTAGTTCCAAAAGTTATTCGTA
ATGATAACCGCTACATAGGTAATGAAGGTAGCAAAAATGATTGA

Upstream 100 bases:

>100_bases
CCAACAGCAGAAGCGTTGTTATATGGCATTATTCAACTACAGAATAAAATCAGGCGGAAACCTGTTTTAGAGGCATAAGC
TCATTAAGGGTGCAGATTAG

Downstream 100 bases:

>100_bases
ACTTAAAAATTATACCTTGAATTTTGGCCCGCAACATCCTGCTGCACATGGTGTTTTAAGATTGGTTCTTGAGTTAGAGG
GTGAAACTATCGTTCGTGCT

Product: NADH dehydrogenase I subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTKNEYLIEKLQADLANHITELTSAYGEVTIECEVQNLLPVMIELRDREEFSFDQLIDLCGVDYLHYGDYDWETESATEH
GFSRGVERQEAKAYAVNKPRFAVVYHLLSTQKNHRLRVKLFVEESHLIVPSVHHLWKSANWFEREAYDLYGILFDGHPDL
RRLLTDYGFIGHPFRKDFPLSGEVEMRYDAKLQKVIYAPVDIVPRIVVPKVIRNDNRYIGNEGSKND

Sequences:

>Translated_227_residues
MTKNEYLIEKLQADLANHITELTSAYGEVTIECEVQNLLPVMIELRDREEFSFDQLIDLCGVDYLHYGDYDWETESATEH
GFSRGVERQEAKAYAVNKPRFAVVYHLLSTQKNHRLRVKLFVEESHLIVPSVHHLWKSANWFEREAYDLYGILFDGHPDL
RRLLTDYGFIGHPFRKDFPLSGEVEMRYDAKLQKVIYAPVDIVPRIVVPKVIRNDNRYIGNEGSKND
>Mature_226_residues
TKNEYLIEKLQADLANHITELTSAYGEVTIECEVQNLLPVMIELRDREEFSFDQLIDLCGVDYLHYGDYDWETESATEHG
FSRGVERQEAKAYAVNKPRFAVVYHLLSTQKNHRLRVKLFVEESHLIVPSVHHLWKSANWFEREAYDLYGILFDGHPDLR
RLLTDYGFIGHPFRKDFPLSGEVEMRYDAKLQKVIYAPVDIVPRIVVPKVIRNDNRYIGNEGSKND

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=180, Percent_Identity=38.8888888888889, Blast_Score=133, Evalue=1e-31,
Organism=Escherichia coli, GI145693162, Length=79, Percent_Identity=48.1012658227848, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=108, Percent_Identity=52.7777777777778, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32563621, Length=108, Percent_Identity=52.7777777777778, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24656494, Length=182, Percent_Identity=37.9120879120879, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 26533; Mature: 26402

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNEYLIEKLQADLANHITELTSAYGEVTIECEVQNLLPVMIELRDREEFSFDQLIDLC
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHEECCCCCCCHHHHHHHH
GVDYLHYGDYDWETESATEHGFSRGVERQEAKAYAVNKPRFAVVYHLLSTQKNHRLRVKL
CCCCEECCCCCCCCCCHHHHHHHHCCCHHHHHHEECCCCHHHHHHHHHHCCCCCEEEEEE
FVEESHLIVPSVHHLWKSANWFEREAYDLYGILFDGHPDLRRLLTDYGFIGHPFRKDFPL
EEECCCEECCCHHHHHCCCCCHHHHHEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
SGEVEMRYDAKLQKVIYAPVDIVPRIVVPKVIRNDNRYIGNEGSKND
CCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure 
TKNEYLIEKLQADLANHITELTSAYGEVTIECEVQNLLPVMIELRDREEFSFDQLIDLC
CCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHEECCCCCCCHHHHHHHH
GVDYLHYGDYDWETESATEHGFSRGVERQEAKAYAVNKPRFAVVYHLLSTQKNHRLRVKL
CCCCEECCCCCCCCCCHHHHHHHHCCCHHHHHHEECCCCHHHHHHHHHHCCCCCEEEEEE
FVEESHLIVPSVHHLWKSANWFEREAYDLYGILFDGHPDLRRLLTDYGFIGHPFRKDFPL
EEECCCEECCCHHHHHCCCCCHHHHHEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
SGEVEMRYDAKLQKVIYAPVDIVPRIVVPKVIRNDNRYIGNEGSKND
CCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA