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The map label for this gene is aas [H]

Identifier: 148360755

GI number: 148360755

Start: 721746

End: 722468

Strand: Direct

Name: aas [H]

Synonym: LPC_2705

Alternate gene names: 148360755

Gene position: 721746-722468 (Clockwise)

Preceding gene: 148360757

Following gene: 148360754

Centisome position: 20.18

GC content: 36.1

Gene sequence:

>723_bases
ATGATGACAAAAACAAATGAGGAAAATTTGACCTGGAAGGGAAAACAAAAACAGCGGGCCAGAAGATGGATAAAAATTTT
TCTGGAGAAATGGTTTCGCATAGAGGTTAAAGGACAATATCAGGCCAACAGCCATTCTGTCATTATTGCCAACAGGGCTT
CTATAATTGATGTGTTACTCCTTTCTGTATTTTTACCTGAACGATTAACTTTAGCTTTACATCCTGATATGTTTAAAAAA
ATATGGGTAAAAACGTTATTATTTTTTGCTGATGTCATAGTAGTTGATCCAGGCAGCGCTCAGGCAACAAGAATTTTAAT
AAGGGCAATACGGGCTGGCAAGCGTTGTCTTCTATTTCCACAAGGGTTATTAAGACAGCAGGAAGACAGCTTAAAGGCCT
TTGCAGGACCTGGATTGATACTCCAAAAGGTTGGCGCCGAGGTAATCCCTGTTCGTATTGAAGGGGCGGAGCACAGTATT
TTTTCTAATAGCAAAAATAAATATCTAATACGGATTTTTCCGAAAATTACTCTTCATATATTACCTGCTCAAAAATTGAG
TCAATCTGAAAATACAGGTGTCGACAGAGAAGGTATCAGTTTACGTTTATTTCAACTAATAAGTGATTTGTCATTCGCCA
ATAGTTTTAAGCCATATGTTTTATTTTCTGCTTTAATTGAAGGAGTAAGTATAGGAACTAAAAACAAAACTAAAATAACG
TGA

Upstream 100 bases:

>100_bases
TAAATTTTTTAAATGAAATCAACATGATTCATAAACCTATCTATTCAAATCGTTTTGAATCTTGCAGAATAAAAGTCAAT
ATAGAGATAACTGATGCGAC

Downstream 100 bases:

>100_bases
ATTCGATATAACTGCTCAAACAACAGCCATAAAAGATCGTTGAATATTTAAAGAGGGCTTCTTTGGTTTAAGTGCATAAG
CAGCTAAACCGGCCAATATA

Product: 2-acylglycerophosphoethanolamine acyltransferase

Products: NA

Alternate protein names: 2-acylglycerophosphoethanolamine acyltransferase; 2-acyl-GPE acyltransferase; Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase; Acyl-[acyl-carrier-protein] synthetase; Acyl-ACP synthetase; Long-chain-fatty-acid--[acyl-carrier-protein] ligase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MMTKTNEENLTWKGKQKQRARRWIKIFLEKWFRIEVKGQYQANSHSVIIANRASIIDVLLLSVFLPERLTLALHPDMFKK
IWVKTLLFFADVIVVDPGSAQATRILIRAIRAGKRCLLFPQGLLRQQEDSLKAFAGPGLILQKVGAEVIPVRIEGAEHSI
FSNSKNKYLIRIFPKITLHILPAQKLSQSENTGVDREGISLRLFQLISDLSFANSFKPYVLFSALIEGVSIGTKNKTKIT

Sequences:

>Translated_240_residues
MMTKTNEENLTWKGKQKQRARRWIKIFLEKWFRIEVKGQYQANSHSVIIANRASIIDVLLLSVFLPERLTLALHPDMFKK
IWVKTLLFFADVIVVDPGSAQATRILIRAIRAGKRCLLFPQGLLRQQEDSLKAFAGPGLILQKVGAEVIPVRIEGAEHSI
FSNSKNKYLIRIFPKITLHILPAQKLSQSENTGVDREGISLRLFQLISDLSFANSFKPYVLFSALIEGVSIGTKNKTKIT
>Mature_240_residues
MMTKTNEENLTWKGKQKQRARRWIKIFLEKWFRIEVKGQYQANSHSVIIANRASIIDVLLLSVFLPERLTLALHPDMFKK
IWVKTLLFFADVIVVDPGSAQATRILIRAIRAGKRCLLFPQGLLRQQEDSLKAFAGPGLILQKVGAEVIPVRIEGAEHSI
FSNSKNKYLIRIFPKITLHILPAQKLSQSENTGVDREGISLRLFQLISDLSFANSFKPYVLFSALIEGVSIGTKNKTKIT

Specific function: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent AMP-binding enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1789201, Length=161, Percent_Identity=36.0248447204969, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF01553 Acyltransferase; PF00501 AMP-binding [H]

EC number: =2.3.1.40; =6.2.1.20 [H]

Molecular weight: Translated: 27228; Mature: 27228

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTKTNEENLTWKGKQKQRARRWIKIFLEKWFRIEVKGQYQANSHSVIIANRASIIDVLL
CCCCCCCCCCEECCHHHHHHHHHHHHHHHHHEEEEEEECEECCCCEEEEECHHHHHHHHH
LSVFLPERLTLALHPDMFKKIWVKTLLFFADVIVVDPGSAQATRILIRAIRAGKRCLLFP
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCEEEECC
QGLLRQQEDSLKAFAGPGLILQKVGAEVIPVRIEGAEHSIFSNSKNKYLIRIFPKITLHI
HHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEEEECCCCHHHCCCCCCEEEEEECEEEEEE
LPAQKLSQSENTGVDREGISLRLFQLISDLSFANSFKPYVLFSALIEGVSIGTKNKTKIT
ECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMTKTNEENLTWKGKQKQRARRWIKIFLEKWFRIEVKGQYQANSHSVIIANRASIIDVLL
CCCCCCCCCCEECCHHHHHHHHHHHHHHHHHEEEEEEECEECCCCEEEEECHHHHHHHHH
LSVFLPERLTLALHPDMFKKIWVKTLLFFADVIVVDPGSAQATRILIRAIRAGKRCLLFP
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCEEEECC
QGLLRQQEDSLKAFAGPGLILQKVGAEVIPVRIEGAEHSIFSNSKNKYLIRIFPKITLHI
HHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEEEECCCCHHHCCCCCCEEEEEECEEEEEE
LPAQKLSQSENTGVDREGISLRLFQLISDLSFANSFKPYVLFSALIEGVSIGTKNKTKIT
ECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA