Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 148360757

GI number: 148360757

Start: 720066

End: 720881

Strand: Direct

Name: ilvE [H]

Synonym: LPC_2707

Alternate gene names: 148360757

Gene position: 720066-720881 (Clockwise)

Preceding gene: 148360758

Following gene: 148360755

Centisome position: 20.13

GC content: 38.48

Gene sequence:

>816_bases
ATGCCTACTCGTGTTATTGAAGACAAAGGAGATATGACGCCATCATTTGGAATTGATGATCGAATTTTTTTAGGTGAGGG
ATTATTTGAAACAATTAGAGTCAATAGTTCCAAGCCTTCCTTTGCTTATATGCATTGGGAGAGACTAGGCAATTCAGCTC
GTCAGTTGGGTATTCCTTTTGAAATTTCATTTGATGATTGGTTTGAGCATCTTATTCAAAAAATCCAAAAAGATAACCTG
TACCATGGTGGCATTAAAGCCATTTTGAGTGGTGGTCCTGCTTCGAGAGGCTTGGCAGAACGAGGGCAAGTCAGCCAATT
AATATTTCAGACTTTCAATTATTCAATACAAAAGCATCCTGTTCGGTTAATCAGTATTAATTGGCTAAGGGATAAGGCCA
ATCCTCTTTATCAATTAAAATCAGTGAATTATTTAGAGGCGATTATTGCTCAACGTCAAGCGATCGCGGTTGGGGCAGAC
GATGCCTTATTTTTCAACACAGAGAATCATGTTACTGAAACAACTTGCGCCAATTTATTCTTGATTGAAAATAACATTTT
GTATACCCCGCGAATAGAGGATGGGATCTTACCCGGCATTACCAGGGCACGCCTCATTTCACATTGTCAGCAACACAAAA
TGTCAGTGCAGGAAATATCATTAACGAAAAAGAGGATTGAGGACGCCGATGCTGTTTTTTTAACTAATAGTCTGCAGGGT
ATCAGAAGGGTGCTCTCCCTGGATAACATTATTTTTGAAGTCAATCATCCAATTATCGATAAGTTGATCTTTTTATTAAA
TCAGGATGAGTCTTGA

Upstream 100 bases:

>100_bases
GTCAGTTTGGATGCGCGCAGACGACTGGAAAATATGTTGGAGGAAAAGCGATTGCGGGATGAGTTGGATGATTTTGTAGA
TTATTAATTATGAGATCATA

Downstream 100 bases:

>100_bases
TAAATTTTTATTAATTGAAAAAACAACTATCTTTTTTTCATTATTCTGATAACAAGTAAAAAGAAAATCGCTAATCCAGT
TAGAAAAACTCCACCATTCC

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MPTRVIEDKGDMTPSFGIDDRIFLGEGLFETIRVNSSKPSFAYMHWERLGNSARQLGIPFEISFDDWFEHLIQKIQKDNL
YHGGIKAILSGGPASRGLAERGQVSQLIFQTFNYSIQKHPVRLISINWLRDKANPLYQLKSVNYLEAIIAQRQAIAVGAD
DALFFNTENHVTETTCANLFLIENNILYTPRIEDGILPGITRARLISHCQQHKMSVQEISLTKKRIEDADAVFLTNSLQG
IRRVLSLDNIIFEVNHPIIDKLIFLLNQDES

Sequences:

>Translated_271_residues
MPTRVIEDKGDMTPSFGIDDRIFLGEGLFETIRVNSSKPSFAYMHWERLGNSARQLGIPFEISFDDWFEHLIQKIQKDNL
YHGGIKAILSGGPASRGLAERGQVSQLIFQTFNYSIQKHPVRLISINWLRDKANPLYQLKSVNYLEAIIAQRQAIAVGAD
DALFFNTENHVTETTCANLFLIENNILYTPRIEDGILPGITRARLISHCQQHKMSVQEISLTKKRIEDADAVFLTNSLQG
IRRVLSLDNIIFEVNHPIIDKLIFLLNQDES
>Mature_270_residues
PTRVIEDKGDMTPSFGIDDRIFLGEGLFETIRVNSSKPSFAYMHWERLGNSARQLGIPFEISFDDWFEHLIQKIQKDNLY
HGGIKAILSGGPASRGLAERGQVSQLIFQTFNYSIQKHPVRLISINWLRDKANPLYQLKSVNYLEAIIAQRQAIAVGADD
ALFFNTENHVTETTCANLFLIENNILYTPRIEDGILPGITRARLISHCQQHKMSVQEISLTKKRIEDADAVFLTNSLQGI
RRVLSLDNIIFEVNHPIIDKLIFLLNQDES

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=252, Percent_Identity=26.5873015873016, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994963, Length=239, Percent_Identity=25.9414225941423, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 30853; Mature: 30722

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRVIEDKGDMTPSFGIDDRIFLGEGLFETIRVNSSKPSFAYMHWERLGNSARQLGIPF
CCCCEECCCCCCCCCCCCCCEEEECCCCEEHEEECCCCCCCHHHHHHHHCCHHHHCCCCE
EISFDDWFEHLIQKIQKDNLYHGGIKAILSGGPASRGLAERGQVSQLIFQTFNYSIQKHP
EECHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCCHHCCC
VRLISINWLRDKANPLYQLKSVNYLEAIIAQRQAIAVGADDALFFNTENHVTETTCANLF
EEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHEEECCCCEEEECCCCCEEHHHHEEEE
LIENNILYTPRIEDGILPGITRARLISHCQQHKMSVQEISLTKKRIEDADAVFLTNSLQG
EEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEHHHHHH
IRRVLSLDNIIFEVNHPIIDKLIFLLNQDES
HHHHHHHHHEEEECCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PTRVIEDKGDMTPSFGIDDRIFLGEGLFETIRVNSSKPSFAYMHWERLGNSARQLGIPF
CCCEECCCCCCCCCCCCCCEEEECCCCEEHEEECCCCCCCHHHHHHHHCCHHHHCCCCE
EISFDDWFEHLIQKIQKDNLYHGGIKAILSGGPASRGLAERGQVSQLIFQTFNYSIQKHP
EECHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCCHHCCC
VRLISINWLRDKANPLYQLKSVNYLEAIIAQRQAIAVGADDALFFNTENHVTETTCANLF
EEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHEEECCCCEEEECCCCCEEHHHHEEEE
LIENNILYTPRIEDGILPGITRARLISHCQQHKMSVQEISLTKKRIEDADAVFLTNSLQG
EEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEHHHHHH
IRRVLSLDNIIFEVNHPIIDKLIFLLNQDES
HHHHHHHHHEEEECCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]