Click here to switch to the map view.

The map label for this gene is proP [C]

Identifier: 148359663

GI number: 148359663

Start: 2461157

End: 2461687

Strand: Direct

Name: proP [C]

Synonym: LPC_1582

Alternate gene names: 148359663

Gene position: 2461157-2461687 (Clockwise)

Preceding gene: 148359662

Following gene: 148359668

Centisome position: 68.82

GC content: 35.59

Gene sequence:

>531_bases
ATGAATGTTTATTATGCTTCTCATTTGGCAAAATACACTACGTTGTCAGAGGCTCAAACCAAATTCGTTGTTACCTTAGG
GCAAGGATTAGTTGTACTATTCATTGTTTTAACAGGAATGTATGCTGATCGAATTGACGAAAGACATATTATAAAAACCG
GTTTGTGGGGGTATTTTATTGCGGCTCCTGTTGCTTTCCTGATACCTCAAACCAATTCTTTTGCATTAATTCTCTTATCG
CAGATTCCCTATGCATTATGCAATGCTCTGGTCGGCACACCAATTTTTAAACTATTGAATGATTTTTTTCCAACTCAGAT
TCGATATAGCGGTGTTTCTGTTGCATGGGGAGTAAGCATGGCTATTTTTGGAGGAACAGCGCCATTGGTTGCCAATTATT
TACAATATTCATTCAAATTAACAACTGCGCCAATATTCTATATACTTTTATCTGCCAGTATTGCCTTGTTCATTTTGCAT
GATAAAAAGAGTTACAAGATAACCTCCATAAAATTAAGATCAGATAATTGA

Upstream 100 bases:

>100_bases
AAACCAAAGAAGCCCTCTTTAAATATTCAACGATCTTTTATGGCTGTTGTTTGAGCAGTTATATCGAATTCACGTTGCAT
TAGGTATTTATATCTACATT

Downstream 100 bases:

>100_bases
ATAAACTACTTATCACCATTGCAAAAACATGTCTACGCAAGCATCTAATCAATTTGTGACAATTGCTTCTTAATAGCCCC
CATTGTTAGAGTCATCATGG

Product: hypothetical protein

Products: betaine [Cytoplasm]; Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: Proline/Betaine Transporter; Facilitator Transporter

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNVYYASHLAKYTTLSEAQTKFVVTLGQGLVVLFIVLTGMYADRIDERHIIKTGLWGYFIAAPVAFLIPQTNSFALILLS
QIPYALCNALVGTPIFKLLNDFFPTQIRYSGVSVAWGVSMAIFGGTAPLVANYLQYSFKLTTAPIFYILLSASIALFILH
DKKSYKITSIKLRSDN

Sequences:

>Translated_176_residues
MNVYYASHLAKYTTLSEAQTKFVVTLGQGLVVLFIVLTGMYADRIDERHIIKTGLWGYFIAAPVAFLIPQTNSFALILLS
QIPYALCNALVGTPIFKLLNDFFPTQIRYSGVSVAWGVSMAIFGGTAPLVANYLQYSFKLTTAPIFYILLSASIALFILH
DKKSYKITSIKLRSDN
>Mature_176_residues
MNVYYASHLAKYTTLSEAQTKFVVTLGQGLVVLFIVLTGMYADRIDERHIIKTGLWGYFIAAPVAFLIPQTNSFALILLS
QIPYALCNALVGTPIFKLLNDFFPTQIRYSGVSVAWGVSMAIFGGTAPLVANYLQYSFKLTTAPIFYILLSASIALFILH
DKKSYKITSIKLRSDN

Specific function: Stretch-Inactivated Proline/Betaine Transporter. Prop Is Both An Osmosensor And An Osmoregulator Which Is Available To Participate Early In The Bacterial Osmoregulatory Response. Mediates The Active Accumulation Of Solutes Such As Proline, Glycine Betaine

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 19546; Mature: 19546

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVYYASHLAKYTTLSEAQTKFVVTLGQGLVVLFIVLTGMYADRIDERHIIKTGLWGYFI
CCEEHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AAPVAFLIPQTNSFALILLSQIPYALCNALVGTPIFKLLNDFFPTQIRYSGVSVAWGVSM
HHHHHHCCCCCCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEHHHHH
AIFGGTAPLVANYLQYSFKLTTAPIFYILLSASIALFILHDKKSYKITSIKLRSDN
EEECCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEEECCC
>Mature Secondary Structure
MNVYYASHLAKYTTLSEAQTKFVVTLGQGLVVLFIVLTGMYADRIDERHIIKTGLWGYFI
CCEEHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AAPVAFLIPQTNSFALILLSQIPYALCNALVGTPIFKLLNDFFPTQIRYSGVSVAWGVSM
HHHHHHCCCCCCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEHHHHH
AIFGGTAPLVANYLQYSFKLTTAPIFYILLSASIALFILHDKKSYKITSIKLRSDN
EEECCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: betaine [Periplasm]; Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + betaine [Periplasm] = Proton [Cytoplasm] + betaine [Cytoplasm] Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA