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The map label for this gene is pcpR [H]

Identifier: 148359668

GI number: 148359668

Start: 2469483

End: 2470397

Strand: Direct

Name: pcpR [H]

Synonym: LPC_1587

Alternate gene names: 148359668

Gene position: 2469483-2470397 (Clockwise)

Preceding gene: 148359663

Following gene: 148359671

Centisome position: 69.05

GC content: 34.21

Gene sequence:

>915_bases
ATGGATCTCAGAAAAATTAATCTCAACTTGTTATTGCATCTTGATACATTGTTAAATGAGCTCTCAGTATCCAAAGCAGC
TGAGAAATCTTTCATGAGCCAGACTGCAATGAGCCATATATTAAAACAATTACGTGATATATTCGATGACCCTTTGTTTA
TTAGGAAACCGCACGGGCTTCAACCAACACAAAAGGCACTTGATCTGGCCCCCAAGATTAAAAAATTTTTAAATTACTCC
AATGATATTTTTGAAGAAGATACTTTCAATCCAGGAAATGACAATTTATTTTTAAAGACTGCATCAGTAGGTACAGGGGA
ATATTTTATTTTACCCAGGTTATGTGCTCATTTGGCTAAAAATGCTCCGAAATTTGTATTAAAGATTTCTTCACTGTCAG
AGTACTTGAGTCTCGAGTATTTATTAATGTCCGAATTAGACTTTGCAATAGGACCAGGTTTTGTTGAAACGGGGAATAAC
ATCATCAGAGAATTATTGTTTGAAGAGGAGGCCGTGTGCGTCATGCACAAATCTCATCCTCTCGCAAATCAGGAGTTAAC
TCAAGATATGTACTTGCAAGCTGAACATGTTGACATACAATTTAGTTACATGGGAAATGAAAATATACTATATAAAGCGT
TACAAGGATATCATCAAAGAAATATCAAAGTGATAGTACCCAATATCATTAGCGCATTGGAAGTGGTTTATCATACGAAT
TTCATTACAACTGTACCGAGAACTCTAGCTGTTACTTTCAAAGACAGATATCAAATTGAACTACACCCTTTGCCTTTCCC
TAAAAAGACATTTTTAGTTAATTTTTACTATCATAAACGATTATCAAATCATAAACCGCTGCAATGGGTATTGGATGTAA
TAAAAAAATATTGTTGCATCAATCATGAGGCTTAA

Upstream 100 bases:

>100_bases
AAGAAAAAGATATGGTCGGTAAATTCCAAATTGTAGTTTTTGGGCTTATTCAGTTACCCTGGATAGGAGTATAAAAAAGT
TAATTTGGATTTAATGAAAA

Downstream 100 bases:

>100_bases
ACAAATTGATATTTAAGGAGAAAGCAAATTCTTCTCCCAATTGTTTTTTATAAAACAATATTCTACGACATCGGACAATT
CATCCGTTCTATAAGTATAA

Product: LysR family transporter transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDLRKINLNLLLHLDTLLNELSVSKAAEKSFMSQTAMSHILKQLRDIFDDPLFIRKPHGLQPTQKALDLAPKIKKFLNYS
NDIFEEDTFNPGNDNLFLKTASVGTGEYFILPRLCAHLAKNAPKFVLKISSLSEYLSLEYLLMSELDFAIGPGFVETGNN
IIRELLFEEEAVCVMHKSHPLANQELTQDMYLQAEHVDIQFSYMGNENILYKALQGYHQRNIKVIVPNIISALEVVYHTN
FITTVPRTLAVTFKDRYQIELHPLPFPKKTFLVNFYYHKRLSNHKPLQWVLDVIKKYCCINHEA

Sequences:

>Translated_304_residues
MDLRKINLNLLLHLDTLLNELSVSKAAEKSFMSQTAMSHILKQLRDIFDDPLFIRKPHGLQPTQKALDLAPKIKKFLNYS
NDIFEEDTFNPGNDNLFLKTASVGTGEYFILPRLCAHLAKNAPKFVLKISSLSEYLSLEYLLMSELDFAIGPGFVETGNN
IIRELLFEEEAVCVMHKSHPLANQELTQDMYLQAEHVDIQFSYMGNENILYKALQGYHQRNIKVIVPNIISALEVVYHTN
FITTVPRTLAVTFKDRYQIELHPLPFPKKTFLVNFYYHKRLSNHKPLQWVLDVIKKYCCINHEA
>Mature_304_residues
MDLRKINLNLLLHLDTLLNELSVSKAAEKSFMSQTAMSHILKQLRDIFDDPLFIRKPHGLQPTQKALDLAPKIKKFLNYS
NDIFEEDTFNPGNDNLFLKTASVGTGEYFILPRLCAHLAKNAPKFVLKISSLSEYLSLEYLLMSELDFAIGPGFVETGNN
IIRELLFEEEAVCVMHKSHPLANQELTQDMYLQAEHVDIQFSYMGNENILYKALQGYHQRNIKVIVPNIISALEVVYHTN
FITTVPRTLAVTFKDRYQIELHPLPFPKKTFLVNFYYHKRLSNHKPLQWVLDVIKKYCCINHEA

Specific function: Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation. Essential for PCP degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=304, Percent_Identity=24.3421052631579, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790147, Length=299, Percent_Identity=24.7491638795987, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081766, Length=297, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786820, Length=76, Percent_Identity=43.421052631579, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35142; Mature: 35142

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRKINLNLLLHLDTLLNELSVSKAAEKSFMSQTAMSHILKQLRDIFDDPLFIRKPHGL
CCCEEEEHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
QPTQKALDLAPKIKKFLNYSNDIFEEDTFNPGNDNLFLKTASVGTGEYFILPRLCAHLAK
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHC
NAPKFVLKISSLSEYLSLEYLLMSELDFAIGPGFVETGNNIIRELLFEEEAVCVMHKSHP
CCCEEEEEHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCHHHHHHHHHCCCCEEEEECCCC
LANQELTQDMYLQAEHVDIQFSYMGNENILYKALQGYHQRNIKVIVPNIISALEVVYHTN
CCHHHHHHHHHEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCC
FITTVPRTLAVTFKDRYQIELHPLPFPKKTFLVNFYYHKRLSNHKPLQWVLDVIKKYCCI
HHHHCCCEEEEEECCCEEEEEECCCCCCHHEEEEHHHHHHCCCCCCHHHHHHHHHHHHHC
NHEA
CCCC
>Mature Secondary Structure
MDLRKINLNLLLHLDTLLNELSVSKAAEKSFMSQTAMSHILKQLRDIFDDPLFIRKPHGL
CCCEEEEHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
QPTQKALDLAPKIKKFLNYSNDIFEEDTFNPGNDNLFLKTASVGTGEYFILPRLCAHLAK
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHC
NAPKFVLKISSLSEYLSLEYLLMSELDFAIGPGFVETGNNIIRELLFEEEAVCVMHKSHP
CCCEEEEEHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCHHHHHHHHHCCCCEEEEECCCC
LANQELTQDMYLQAEHVDIQFSYMGNENILYKALQGYHQRNIKVIVPNIISALEVVYHTN
CCHHHHHHHHHEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCC
FITTVPRTLAVTFKDRYQIELHPLPFPKKTFLVNFYYHKRLSNHKPLQWVLDVIKKYCCI
HHHHCCCEEEEEECCCEEEEEECCCCCCHHEEEEHHHHHHCCCCCCHHHHHHHHHHHHHC
NHEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12169590 [H]