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The map label for this gene is corC [H]

Identifier: 148358970

GI number: 148358970

Start: 1653449

End: 1654306

Strand: Reverse

Name: corC [H]

Synonym: LPC_0855

Alternate gene names: 148358970

Gene position: 1654306-1653449 (Counterclockwise)

Preceding gene: 148358971

Following gene: 148358969

Centisome position: 46.26

GC content: 35.78

Gene sequence:

>858_bases
TTGAATAAATTGGAAGATGGTGGGTCGTGGTTTTCTCGTTTAAAACAGTTCTTACAAGGAGAGCCACAAAATCAGGAAGA
ATTGGTCAGTTTATTAAGAGACGCGCAAATACGCTCCCTGATTAATTCAGAGACCCTCGCAATGATTGAGGGAGCTATCC
TTTTCTCAAAAATGCGTGTTCGAGACATCATGCTGCCTAAAAATCAAATGGTTTGCATTAATAAGGATGATGATTTTAAG
CATATTATATCTATTGTAACTCAAACGGGACATTCACGTTTTCCTGTAACGAGTGAAAATTCTGATGAAGTGGTTGGCAT
TTTGCACGCAAAGGATTTGTTAAAATATCAACCAGAAAATATGGAATCATTTGATTTATTGGACATCTGCCGCCAGGTAA
CTTTTGTACCTGAAAGCAGACGTCTTGATAGTCTGCTTAGTGAATTTCGAAGTAATAGAAATCATATGGCTATTGTTGTT
GATGAATATGGAGAGGTGTCAGGTTTCGTTACCATTGAAGATATCATTGAACAAATAATCGGTGACATAGAAGATGAATT
TGATATCGATGAAGACGCCTATATTAAAGCACATGAAGGACACTGCTATATCATCAAAGCCCATACTCCAATAGAAGAAT
TTAACGAACAGCTCAACGCTGATTTTAGTGACGAAACCTATGATACAATTGGTGGCATAGTATTAAATAAATTCGGCTAT
TTACCTCAACGAGGTGAAGTAATAATCATAGATGATTTTGAATTTAAAGTTCTTAATGCCGATTCGAGAAGAATAAAGTT
ATTAGAATGTCTCGATAAAAGAAGTCCCGAGAAACTAAATTCTACTGTTGAAGGATAA

Upstream 100 bases:

>100_bases
CATATAAAAGATGAAGAAGCCTCTATTATGCAAATGCTCGAAGCTAAATTACTAGCTGAATTAGGTTATGCTAATCCATA
TGAAGTCGAGGAAAATGAAC

Downstream 100 bases:

>100_bases
GTAATTCATGAGCAGCTCTATTCTCATTATTGATGATGACACAGAACTAACAGATTTATTAACCCAATATTTGGAGCCAG
AAGGCTTTAATGTAGTATGT

Product: Mg2+ and Co2+ transporter CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCINKDDDFK
HIISIVTQTGHSRFPVTSENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVV
DEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY
LPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG

Sequences:

>Translated_285_residues
MNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCINKDDDFK
HIISIVTQTGHSRFPVTSENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVV
DEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY
LPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
>Mature_285_residues
MNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCINKDDDFK
HIISIVTQTGHSRFPVTSENSDEVVGILHAKDLLKYQPENMESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVV
DEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY
LPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=216, Percent_Identity=26.8518518518519, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI94681046, Length=200, Percent_Identity=33, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40068055, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40068053, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40068049, Length=150, Percent_Identity=32.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=48.015873015873, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI145693175, Length=245, Percent_Identity=25.7142857142857, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082033, Length=265, Percent_Identity=27.1698113207547, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788119, Length=229, Percent_Identity=26.6375545851528, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790664, Length=222, Percent_Identity=25.6756756756757, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32709; Mature: 32709

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRV
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTSENSDEVVGILHAKDLLKYQPEN
HHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCC
MESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGFVTIEDIIEQII
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHH
GDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY
HCCHHHCCCCCCCEEEEECCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
LPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
CCCCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MNKLEDGGSWFSRLKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRV
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTSENSDEVVGILHAKDLLKYQPEN
HHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCC
MESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGFVTIEDIIEQII
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHH
GDIEDEFDIDEDAYIKAHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY
HCCHHHCCCCCCCEEEEECCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
LPQRGEVIIIDDFEFKVLNADSRRIKLLECLDKRSPEKLNSTVEG
CCCCCCEEEEECCEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]