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The map label for this gene is hflX [H]

Identifier: 148358150

GI number: 148358150

Start: 13339

End: 14583

Strand: Direct

Name: hflX [H]

Synonym: LPC_0011

Alternate gene names: 148358150

Gene position: 13339-14583 (Clockwise)

Preceding gene: 148358149

Following gene: 148358153

Centisome position: 0.37

GC content: 43.53

Gene sequence:

>1245_bases
GTGTTTGAACGTCCACAAGGCGGTGAGCGAGCTGTTTTGGTGCAGTTAGCTCTCCCCGGGGTTGATGCTGATAAGGCATT
GGCTGAGTTTGAAGAGTTAGCGCTTTCGGCGAAGGCTGAGGTGTTGGATTGTGTATTAGGTGCCCGAGCTACTCCCGATG
CCAAATATTATGTAGGGAAAGGTAAGGCTGAGGAAATAGCTCATTTGGTAAACATGCTCGATGCGGATTTAGTGTTAGTC
AATCATGAGCTATCGCCTTCTCAAGAGCGGAATCTCGAGCGATTATTTGGATGTCGAGTTGTCGATAGAAGTGGCTTGAT
TCTTGATATTTTTGCTCAGAGAGCTCGTACTTTTGAGGGTAAACTTCAAGTTGAGCTAGCCCAATTGCAACATTTATCAA
CAAGGCTTATTCGTGGATGGACCCATTTGGAAAGGCAAAAAGGAGGGATTGGTTTAAGAGGCCCAGGAGAAACCCAATTG
GAAACGGACCGGCGTTTGTTAAGAGAGCGCATTCGTTATATTAATAAGCGATTGGAAAAAGTACGCTGCAGCCGCGATCA
AAACAGGCAGGCCAGGCGGAAGGCGTCCATGCCTACTGTTTCTCTAGTGGGTTACACCAATGCCGGAAAATCCACTTTAT
TTAATGTTTTAACAGGGGAACACACTTATGTGGCTGATCAATTGTTTGCAACCCTGGATCCGACGATGCGTAAATTGGAA
TTGCCAGGGTCCTCAGCAGCAATTTTAGCAGATACAGTAGGGTTTATTCGAGATCTTCCCCATCACTTGGTAGAAGCATT
CCGCGCTACTTTAGAGGAAACCCAACAAGCCGATCTATTATTGCATGTCATTGATATTTCTGACCCGAATTGGCGAGAGA
CGGTTTTTGAAGTACAAAAGGTGTTAGATGAATTAAAGGTTAGTAATATCCCGGTAATTCAGGTGTTTAATAAAATTGAT
TTGCAGGAAGGCTGGCAACCAAAAATTGATTATACTGAGGATGCTTGCAAGGTATGGTTATCAGCAACAACCGGCGCTGG
TCTGGATCTTCTAAAAGAGGCAATAGCAACTCAATTGCATGGTATGATTTTAATTGAGGATATTGTAATTAAGCCTGACC
AGGCAAAATTACGAGCCCAATTATACCAATTAGGCGCTGTACTTAAAGAGTCTGTAGATGAAAACGGCGATTGGTTAATG
AAAATTAGAATAACGGCTGATCAAAAACGACGATTGCTTTCATGA

Upstream 100 bases:

>100_bases
TGTTCCTTCTCGAATGGTCAAAATTCCTGCTGAGGAAAGCTCTGGTGAGGAAGAAGGAACTGTGGCAGACTAATCAATTT
CTTGTTTGGGGATTAGGGTA

Downstream 100 bases:

>100_bases
ATAATCAAGTCAGGCTGCGGGGCGATAGAATCGATTCCGGACTTGATAAATTCACAATAAAATTTTTAACTGATTGACCA
AAAATATAATTTTTATTTAT

Product: GTP binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MFERPQGGERAVLVQLALPGVDADKALAEFEELALSAKAEVLDCVLGARATPDAKYYVGKGKAEEIAHLVNMLDADLVLV
NHELSPSQERNLERLFGCRVVDRSGLILDIFAQRARTFEGKLQVELAQLQHLSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIRYINKRLEKVRCSRDQNRQARRKASMPTVSLVGYTNAGKSTLFNVLTGEHTYVADQLFATLDPTMRKLE
LPGSSAAILADTVGFIRDLPHHLVEAFRATLEETQQADLLLHVIDISDPNWRETVFEVQKVLDELKVSNIPVIQVFNKID
LQEGWQPKIDYTEDACKVWLSATTGAGLDLLKEAIATQLHGMILIEDIVIKPDQAKLRAQLYQLGAVLKESVDENGDWLM
KIRITADQKRRLLS

Sequences:

>Translated_414_residues
MFERPQGGERAVLVQLALPGVDADKALAEFEELALSAKAEVLDCVLGARATPDAKYYVGKGKAEEIAHLVNMLDADLVLV
NHELSPSQERNLERLFGCRVVDRSGLILDIFAQRARTFEGKLQVELAQLQHLSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIRYINKRLEKVRCSRDQNRQARRKASMPTVSLVGYTNAGKSTLFNVLTGEHTYVADQLFATLDPTMRKLE
LPGSSAAILADTVGFIRDLPHHLVEAFRATLEETQQADLLLHVIDISDPNWRETVFEVQKVLDELKVSNIPVIQVFNKID
LQEGWQPKIDYTEDACKVWLSATTGAGLDLLKEAIATQLHGMILIEDIVIKPDQAKLRAQLYQLGAVLKESVDENGDWLM
KIRITADQKRRLLS
>Mature_414_residues
MFERPQGGERAVLVQLALPGVDADKALAEFEELALSAKAEVLDCVLGARATPDAKYYVGKGKAEEIAHLVNMLDADLVLV
NHELSPSQERNLERLFGCRVVDRSGLILDIFAQRARTFEGKLQVELAQLQHLSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIRYINKRLEKVRCSRDQNRQARRKASMPTVSLVGYTNAGKSTLFNVLTGEHTYVADQLFATLDPTMRKLE
LPGSSAAILADTVGFIRDLPHHLVEAFRATLEETQQADLLLHVIDISDPNWRETVFEVQKVLDELKVSNIPVIQVFNKID
LQEGWQPKIDYTEDACKVWLSATTGAGLDLLKEAIATQLHGMILIEDIVIKPDQAKLRAQLYQLGAVLKESVDENGDWLM
KIRITADQKRRLLS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=226, Percent_Identity=40.2654867256637, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI310133118, Length=226, Percent_Identity=39.3805309734513, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI310124269, Length=208, Percent_Identity=41.3461538461538, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI310124267, Length=208, Percent_Identity=41.3461538461538, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI310124171, Length=208, Percent_Identity=41.3461538461538, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI310124169, Length=208, Percent_Identity=41.3461538461538, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1790615, Length=414, Percent_Identity=56.5217391304348, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17561038, Length=278, Percent_Identity=33.4532374100719, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24650079, Length=369, Percent_Identity=33.0623306233062, Blast_Score=125, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 46552; Mature: 46552

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERPQGGERAVLVQLALPGVDADKALAEFEELALSAKAEVLDCVLGARATPDAKYYVGK
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GKAEEIAHLVNMLDADLVLVNHELSPSQERNLERLFGCRVVDRSGLILDIFAQRARTFEG
CCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCC
KLQVELAQLQHLSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIRYINKRLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VRCSRDQNRQARRKASMPTVSLVGYTNAGKSTLFNVLTGEHTYVADQLFATLDPTMRKLE
HHHCCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCHHHHHEE
LPGSSAAILADTVGFIRDLPHHLVEAFRATLEETQQADLLLHVIDISDPNWRETVFEVQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHH
VLDELKVSNIPVIQVFNKIDLQEGWQPKIDYTEDACKVWLSATTGAGLDLLKEAIATQLH
HHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GMILIEDIVIKPDQAKLRAQLYQLGAVLKESVDENGDWLMKIRITADQKRRLLS
CEEEEEHEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHCCCC
>Mature Secondary Structure
MFERPQGGERAVLVQLALPGVDADKALAEFEELALSAKAEVLDCVLGARATPDAKYYVGK
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GKAEEIAHLVNMLDADLVLVNHELSPSQERNLERLFGCRVVDRSGLILDIFAQRARTFEG
CCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCC
KLQVELAQLQHLSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIRYINKRLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VRCSRDQNRQARRKASMPTVSLVGYTNAGKSTLFNVLTGEHTYVADQLFATLDPTMRKLE
HHHCCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCHHHHHEE
LPGSSAAILADTVGFIRDLPHHLVEAFRATLEETQQADLLLHVIDISDPNWRETVFEVQK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHH
VLDELKVSNIPVIQVFNKIDLQEGWQPKIDYTEDACKVWLSATTGAGLDLLKEAIATQLH
HHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GMILIEDIVIKPDQAKLRAQLYQLGAVLKESVDENGDWLMKIRITADQKRRLLS
CEEEEEHEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]