Click here to switch to the map view.

The map label for this gene is hfq

Identifier: 148358149

GI number: 148358149

Start: 13054

End: 13311

Strand: Direct

Name: hfq

Synonym: LPC_0010

Alternate gene names: 148358149

Gene position: 13054-13311 (Clockwise)

Preceding gene: 148358147

Following gene: 148358150

Centisome position: 0.36

GC content: 38.37

Gene sequence:

>258_bases
ATGTCTAAAAATCATTTACTACAAGACCCTTTCCTAAATGAATTGCGCAAGGAAAAGGTACCTGTTTCAGTGTTCCTGGT
CAATGGTATTAAATTGCATGGGATAATCGATTCTTTTGATCAATATGTGGTGATGCTTAAAAACTCCATAACCCAAATGG
TTTATAAACACGCCATTTCAACAGTTGTTCCTTCTCGAATGGTCAAAATTCCTGCTGAGGAAAGCTCTGGTGAGGAAGAA
GGAACTGTGGCAGACTAA

Upstream 100 bases:

>100_bases
TGTCATGAAAATATACTAAAGTTTTATTATAGGGTGTCGAATAAATAGTTAGATACCCGTTTTTGCCTTTAAAAATTACA
ATAACAACAAGGAGTAGGCA

Downstream 100 bases:

>100_bases
TCAATTTCTTGTTTGGGGATTAGGGTAGTGTTTGAACGTCCACAAGGCGGTGAGCGAGCTGTTTTGGTGCAGTTAGCTCT
CCCCGGGGTTGATGCTGATA

Product: bacteriophage Q beta replication host factor-I protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MSKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAISTVVPSRMVKIPAEESSGEEE
GTVAD

Sequences:

>Translated_85_residues
MSKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAISTVVPSRMVKIPAEESSGEEE
GTVAD
>Mature_84_residues
SKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAISTVVPSRMVKIPAEESSGEEEG
TVAD

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=77, Percent_Identity=64.9350649350649, Blast_Score=111, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_LEGPA (Q5X982)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_122361.1
- ProteinModelPortal:   Q5X982
- SMR:   Q5X982
- STRING:   Q5X982
- GeneID:   3117307
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0009
- LegioList:   lpp0009
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- ProtClustDB:   CLSK831930
- BioCyc:   LPNE297246:LPP0009-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9528; Mature: 9397

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAIS
CCCCCCCCCHHHHHHHHHCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRMVKIPAEESSGEEEGTVAD
HHHCHHHEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAIS
CCCCCCCCHHHHHHHHHCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRMVKIPAEESSGEEEGTVAD
HHHCHHHEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA