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The map label for this gene is nuoN [H]

Identifier: 148285168

GI number: 148285168

Start: 2111204

End: 2112640

Strand: Direct

Name: nuoN [H]

Synonym: OTBS_2166

Alternate gene names: 148285168

Gene position: 2111204-2112640 (Clockwise)

Preceding gene: 148285167

Following gene: 148285169

Centisome position: 99.25

GC content: 28.11

Gene sequence:

>1437_bases
ATGGAAATGTTATATGGTATTATGCCAGAAATTTCGCTTCTTTTATCAGCTTTGATTTTTCAACTAATTGGAGCATATAG
TAACAATACGCTAACTCATGTTATAGCTAAAATGGCAATTGGTTTTGCCGCCATATTAATAGCTATTTTAGTATTTCATC
CTAACTTGTTTAATGGTATTTACTGGAATAATACATTTATTGTTAACCAATCTAAAATATACTTAAAAATTATTATTTTA
ATTTTTTATATATCTCTTACTTTAATTTATTCTGGATATATCAAGGTTGCAAACTTAAAAGGCCATAGTGAATATATAGT
ACTAATGCAGCTTGGAGCTTTAGGAGGATTAATATTGGTTTCAGCTAATGATTTTATGGTTATGTACCTTGGTATTGAGA
TGCAAGGAATAATAGGATATATTTTAACTACTTTTAATTATAATAATTCTAGATCATCTGAAGCTGGTTTAAAATATTTT
ATATTGGGGACAGTTTTCTCAGCTATTATGTTGTTTGGTATATCTTTAGTATATGGTATTACTCAAAGTATAAGGTATGA
TATTGCTTTGCATGCATTGCAAAATCCAAGCTCTGATATTGCTGCGCTAGTGGCTATACTAATGATACTTGTTGGAGTCT
TATTTAAATTATCTATCGCGCCGTTCCATATGTGGACACCTGATATTTATGATGGTGCACCTTTAGTAGTAGTTGCGTTA
TTTTCTAGCTTTCCTAAAATTAGTGTATTAGCATTGCTTGGAAATTTATTATCTGAATTAAAGTTTGCTAGTGAGACCTT
CTTTTATATAAAAATGATAATAATGGTACTTGCATGTCTATCATTAATTGTTGGTGCATTTGGCGCATTATTACAACAAT
CAATTCAAAGGTTTATTGCCTATAGTGCAATATTAAATTTAGGATATGCTGTACTTGCTTTAGTTGCTAACAGCTCTAAT
GTTATTAGAGCTGAAATATCATATTTTTATATTATTATTTATGCTGCTAGTATGTTAGGATTTATTGCGATAATAATAAA
CAATTTTACTAATCGTGCTAATTATTTAAAAATTAGTCATCTTAGTGGATTATCTAATGTAAAAAAATTATCGTCAATAT
TAATAGCAATACAGATGTTCTCATTAGTAGGAATTCCACCTTTTGCAGGGTTTATTAGTAAGTATATCATTTTTACTAGT
ATTTTAAAATCTGGTATGTATGAATTAATAATTATGGGAATAGCAGCAGTTGTGATTGGATCATATTGTTATCTTAATAT
TGTTAAAGTAATGTACTTTTTACCTGCTACAGTCAGGTTTCAGAATTCCAGTATAAATTTTGAGCTAAGCTTAGTAAGTA
TATCTTCAACAGTAATTGTTATATCATTAATGATTATATGTATGTTTTTTGGTGAAGGTTTAAGCGTTATTGTATAA

Upstream 100 bases:

>100_bases
TATTAAACATTTTATTGATACCAGCTAAGAACTTAAGCAGTTTATTTATTATATAAATTGTAATTGCTGTGTACGTTTAA
TTTTATTTGAAAGAGTTATT

Downstream 100 bases:

>100_bases
TGCTTAGTCAAAATGAGATATGGATTATTCAAGTTTGAAACTATTGATAGTATGCAGACAGAAGGGTTTAAAGCTATTTA
ATCAATGAATATTGAGGTGA

Product: NADH dehydrogenase I chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MEMLYGIMPEISLLLSALIFQLIGAYSNNTLTHVIAKMAIGFAAILIAILVFHPNLFNGIYWNNTFIVNQSKIYLKIIIL
IFYISLTLIYSGYIKVANLKGHSEYIVLMQLGALGGLILVSANDFMVMYLGIEMQGIIGYILTTFNYNNSRSSEAGLKYF
ILGTVFSAIMLFGISLVYGITQSIRYDIALHALQNPSSDIAALVAILMILVGVLFKLSIAPFHMWTPDIYDGAPLVVVAL
FSSFPKISVLALLGNLLSELKFASETFFYIKMIIMVLACLSLIVGAFGALLQQSIQRFIAYSAILNLGYAVLALVANSSN
VIRAEISYFYIIIYAASMLGFIAIIINNFTNRANYLKISHLSGLSNVKKLSSILIAIQMFSLVGIPPFAGFISKYIIFTS
ILKSGMYELIIMGIAAVVIGSYCYLNIVKVMYFLPATVRFQNSSINFELSLVSISSTVIVISLMIICMFFGEGLSVIV

Sequences:

>Translated_478_residues
MEMLYGIMPEISLLLSALIFQLIGAYSNNTLTHVIAKMAIGFAAILIAILVFHPNLFNGIYWNNTFIVNQSKIYLKIIIL
IFYISLTLIYSGYIKVANLKGHSEYIVLMQLGALGGLILVSANDFMVMYLGIEMQGIIGYILTTFNYNNSRSSEAGLKYF
ILGTVFSAIMLFGISLVYGITQSIRYDIALHALQNPSSDIAALVAILMILVGVLFKLSIAPFHMWTPDIYDGAPLVVVAL
FSSFPKISVLALLGNLLSELKFASETFFYIKMIIMVLACLSLIVGAFGALLQQSIQRFIAYSAILNLGYAVLALVANSSN
VIRAEISYFYIIIYAASMLGFIAIIINNFTNRANYLKISHLSGLSNVKKLSSILIAIQMFSLVGIPPFAGFISKYIIFTS
ILKSGMYELIIMGIAAVVIGSYCYLNIVKVMYFLPATVRFQNSSINFELSLVSISSTVIVISLMIICMFFGEGLSVIV
>Mature_478_residues
MEMLYGIMPEISLLLSALIFQLIGAYSNNTLTHVIAKMAIGFAAILIAILVFHPNLFNGIYWNNTFIVNQSKIYLKIIIL
IFYISLTLIYSGYIKVANLKGHSEYIVLMQLGALGGLILVSANDFMVMYLGIEMQGIIGYILTTFNYNNSRSSEAGLKYF
ILGTVFSAIMLFGISLVYGITQSIRYDIALHALQNPSSDIAALVAILMILVGVLFKLSIAPFHMWTPDIYDGAPLVVVAL
FSSFPKISVLALLGNLLSELKFASETFFYIKMIIMVLACLSLIVGAFGALLQQSIQRFIAYSAILNLGYAVLALVANSSN
VIRAEISYFYIIIYAASMLGFIAIIINNFTNRANYLKISHLSGLSNVKKLSSILIAIQMFSLVGIPPFAGFISKYIIFTS
ILKSGMYELIIMGIAAVVIGSYCYLNIVKVMYFLPATVRFQNSSINFELSLVSISSTVIVISLMIICMFFGEGLSVIV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=208, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI145693160, Length=372, Percent_Identity=27.6881720430108, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788831, Length=294, Percent_Identity=26.8707482993197, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788614, Length=321, Percent_Identity=23.6760124610592, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52600; Mature: 52600

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMLYGIMPEISLLLSALIFQLIGAYSNNTLTHVIAKMAIGFAAILIAILVFHPNLFNGI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCE
YWNNTFIVNQSKIYLKIIILIFYISLTLIYSGYIKVANLKGHSEYIVLMQLGALGGLILV
EECCEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCCEEEE
SANDFMVMYLGIEMQGIIGYILTTFNYNNSRSSEAGLKYFILGTVFSAIMLFGISLVYGI
ECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TQSIRYDIALHALQNPSSDIAALVAILMILVGVLFKLSIAPFHMWTPDIYDGAPLVVVAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHH
FSSFPKISVLALLGNLLSELKFASETFFYIKMIIMVLACLSLIVGAFGALLQQSIQRFIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSAILNLGYAVLALVANSSNVIRAEISYFYIIIYAASMLGFIAIIINNFTNRANYLKISH
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEH
LSGLSNVKKLSSILIAIQMFSLVGIPPFAGFISKYIIFTSILKSGMYELIIMGIAAVVIG
HCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYCYLNIVKVMYFLPATVRFQNSSINFELSLVSISSTVIVISLMIICMFFGEGLSVIV
HHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MEMLYGIMPEISLLLSALIFQLIGAYSNNTLTHVIAKMAIGFAAILIAILVFHPNLFNGI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCE
YWNNTFIVNQSKIYLKIIILIFYISLTLIYSGYIKVANLKGHSEYIVLMQLGALGGLILV
EECCEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCCEEEE
SANDFMVMYLGIEMQGIIGYILTTFNYNNSRSSEAGLKYFILGTVFSAIMLFGISLVYGI
ECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TQSIRYDIALHALQNPSSDIAALVAILMILVGVLFKLSIAPFHMWTPDIYDGAPLVVVAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHH
FSSFPKISVLALLGNLLSELKFASETFFYIKMIIMVLACLSLIVGAFGALLQQSIQRFIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSAILNLGYAVLALVANSSNVIRAEISYFYIIIYAASMLGFIAIIINNFTNRANYLKISH
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEH
LSGLSNVKKLSSILIAIQMFSLVGIPPFAGFISKYIIFTSILKSGMYELIIMGIAAVVIG
HCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYCYLNIVKVMYFLPATVRFQNSSINFELSLVSISSTVIVISLMIICMFFGEGLSVIV
HHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA