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The map label for this gene is tlc [H]

Identifier: 148284167

GI number: 148284167

Start: 309345

End: 310889

Strand: Direct

Name: tlc [H]

Synonym: OTBS_0313

Alternate gene names: 148284167

Gene position: 309345-310889 (Clockwise)

Preceding gene: 148284166

Following gene: 148284168

Centisome position: 14.54

GC content: 28.41

Gene sequence:

>1545_bases
ATGCAAAAAACTAACATTTTAAAAAAATTTACAAAAGCTCTATGGCCAATAGAACTTCATGAAATGAAGCTATTTATGCC
AATGGCTTTAATTATATTTTGCCTATTATTTAACTTTAGTGCCTTAAGAGCAATAAAAGATAGCTTAGTTGTACCTTCAG
TAGGAGCTGAAGTTATTAGCTTTCTAAAATTATGGTTAGTGTTACCTTCAGCAATTATATTCACTTTAACATACGTTAAG
TTATCTAATAGTTACTCGATGGAAAATATATTTTATATCATAGTAACATTTTTTTTAATATTCTTTTTACTATTTGCTTT
TATTGTTTATCCAAATGAAATGTTATTACATCCATCAGAGGAGCTAATTAAAGAAGCAATATATAATTATCCGCATTTAC
AGTGGATTATTAGAATTTGTGGAAAATGGAGTTATGCTGTGATGTATATTATCTGCGAACTATGGAGTGTCGTAGTGATT
AATCTGATGTACTGGCAATTTGCTAATAATATGTTTAATATTAAAGATGCCAAAAGATTTTATCCAGCTTTAGGCATGAT
AGGTAATTTAGGGCTAATTGTTGCTGGTAATGTATTAATAGCATGTGCCAATAATTCAGAAATCTCAATAGCATCAGATA
TATTTGTAATCAATAGCGACTGTGCTAAAAATTCCGAAGCAATTTTTAAACATATTGTTATTGTTGTTACGATTTTTGGA
ATTATAGCGATTCTTACCTTTAAGTACTTAAATAACTTAGTATTAGGTAAAGCTGTTATAATGCATAACAAAGATAATCT
AATGAATAATCTTAAGCTATATAATCATGGCACAACTAAATTATCTTTAAAAGATAGTATAAAGTTAATTTTAAGATCTG
ACTATATTAGTCGAATAGCAATTATGGTAATTTGCTATGGTTTATCAATCAATATTTTGGAAGGCCCATGGAAAGCTCAA
ATTAAAGAACTATATCCTACAACGCAGGAATACATTACTTTTATGGGCAAGTTTAATGTTGTTATGGGAATATCTTGTGT
TATGTTTATGGGAATGAGTAGTAGTATATTACATAAATTTAATTGGTTATTTCCAGCTCTGATTACTCCTTTAATTATCG
GAGTGACAGGTATAATATTTTTTCTGTTAATAATTACAGGAGAAACTGCAAGTACAATTTTTAGCACTGTTGGTTATAGT
CCTATTTATTTAGCTGTATTAGTTGGAGCATCGCAAAATATTTTAAGTAAATCAAGTAAATGTTCCTTATTTGATGCAAC
TAAAGAAATTGCATATATTCCACTGGATATTGAAACAAAAATCAAAGGAAAAGCTGCAGTTGAGGTAGTAGGAGCAAAAC
TTGGAAAATCAGGCGGAGCATTTATACAGTTTTTAATTTTAACATTGTATCCAGAATCAACCATTAGCTCTATCTCGGCA
ATTTTAATGGGAGTATTTATACTAGTAGTTTTAATTTGGTTAATTGATGTTGTAAACCTTTATCATAAATATGATGATTT
ACAACAATTTATGGAAAAGAAGTAA

Upstream 100 bases:

>100_bases
ACACCAATTTTAGTCGAATATATCTTATAATTTTGATTTTATTTGTTATGTGTTAAAAGTGAATTTTCTTCTTGTTGCTT
TATCAAATTGATTCAATATA

Downstream 100 bases:

>100_bases
TGAGAAAAGTATATATAATTTTAATTACAAGCATTGTAGTACTATTACTTTTGCTTATTAGTTGGTATGCGGTATGGGAA
ATATTGGCTAATCGAATCAC

Product: ATP/ADP translocase

Products: NA

Alternate protein names: ADP/ATP translocase 3 [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQKTNILKKFTKALWPIELHEMKLFMPMALIIFCLLFNFSALRAIKDSLVVPSVGAEVISFLKLWLVLPSAIIFTLTYVK
LSNSYSMENIFYIIVTFFLIFFLLFAFIVYPNEMLLHPSEELIKEAIYNYPHLQWIIRICGKWSYAVMYIICELWSVVVI
NLMYWQFANNMFNIKDAKRFYPALGMIGNLGLIVAGNVLIACANNSEISIASDIFVINSDCAKNSEAIFKHIVIVVTIFG
IIAILTFKYLNNLVLGKAVIMHNKDNLMNNLKLYNHGTTKLSLKDSIKLILRSDYISRIAIMVICYGLSINILEGPWKAQ
IKELYPTTQEYITFMGKFNVVMGISCVMFMGMSSSILHKFNWLFPALITPLIIGVTGIIFFLLIITGETASTIFSTVGYS
PIYLAVLVGASQNILSKSSKCSLFDATKEIAYIPLDIETKIKGKAAVEVVGAKLGKSGGAFIQFLILTLYPESTISSISA
ILMGVFILVVLIWLIDVVNLYHKYDDLQQFMEKK

Sequences:

>Translated_514_residues
MQKTNILKKFTKALWPIELHEMKLFMPMALIIFCLLFNFSALRAIKDSLVVPSVGAEVISFLKLWLVLPSAIIFTLTYVK
LSNSYSMENIFYIIVTFFLIFFLLFAFIVYPNEMLLHPSEELIKEAIYNYPHLQWIIRICGKWSYAVMYIICELWSVVVI
NLMYWQFANNMFNIKDAKRFYPALGMIGNLGLIVAGNVLIACANNSEISIASDIFVINSDCAKNSEAIFKHIVIVVTIFG
IIAILTFKYLNNLVLGKAVIMHNKDNLMNNLKLYNHGTTKLSLKDSIKLILRSDYISRIAIMVICYGLSINILEGPWKAQ
IKELYPTTQEYITFMGKFNVVMGISCVMFMGMSSSILHKFNWLFPALITPLIIGVTGIIFFLLIITGETASTIFSTVGYS
PIYLAVLVGASQNILSKSSKCSLFDATKEIAYIPLDIETKIKGKAAVEVVGAKLGKSGGAFIQFLILTLYPESTISSISA
ILMGVFILVVLIWLIDVVNLYHKYDDLQQFMEKK
>Mature_514_residues
MQKTNILKKFTKALWPIELHEMKLFMPMALIIFCLLFNFSALRAIKDSLVVPSVGAEVISFLKLWLVLPSAIIFTLTYVK
LSNSYSMENIFYIIVTFFLIFFLLFAFIVYPNEMLLHPSEELIKEAIYNYPHLQWIIRICGKWSYAVMYIICELWSVVVI
NLMYWQFANNMFNIKDAKRFYPALGMIGNLGLIVAGNVLIACANNSEISIASDIFVINSDCAKNSEAIFKHIVIVVTIFG
IIAILTFKYLNNLVLGKAVIMHNKDNLMNNLKLYNHGTTKLSLKDSIKLILRSDYISRIAIMVICYGLSINILEGPWKAQ
IKELYPTTQEYITFMGKFNVVMGISCVMFMGMSSSILHKFNWLFPALITPLIIGVTGIIFFLLIITGETASTIFSTVGYS
PIYLAVLVGASQNILSKSSKCSLFDATKEIAYIPLDIETKIKGKAAVEVVGAKLGKSGGAFIQFLILTLYPESTISSISA
ILMGVFILVVLIWLIDVVNLYHKYDDLQQFMEKK

Specific function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism [H]

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004667 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58035; Mature: 58035

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTNILKKFTKALWPIELHEMKLFMPMALIIFCLLFNFSALRAIKDSLVVPSVGAEVIS
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FLKLWLVLPSAIIFTLTYVKLSNSYSMENIFYIIVTFFLIFFLLFAFIVYPNEMLLHPSE
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHH
ELIKEAIYNYPHLQWIIRICGKWSYAVMYIICELWSVVVINLMYWQFANNMFNIKDAKRF
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YPALGMIGNLGLIVAGNVLIACANNSEISIASDIFVINSDCAKNSEAIFKHIVIVVTIFG
HHHHHHHHCCHHEEECCEEEEECCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
IIAILTFKYLNNLVLGKAVIMHNKDNLMNNLKLYNHGTTKLSLKDSIKLILRSDYISRIA
HHHHHHHHHHHHHHHHHHHEEECCHHHHHCCEEEECCCCEEEHHHHHHHHHHHHHHHHHH
IMVICYGLSINILEGPWKAQIKELYPTTQEYITFMGKFNVVMGISCVMFMGMSSSILHKF
HHHHHHCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NWLFPALITPLIIGVTGIIFFLLIITGETASTIFSTVGYSPIYLAVLVGASQNILSKSSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCC
CSLFDATKEIAYIPLDIETKIKGKAAVEVVGAKLGKSGGAFIQFLILTLYPESTISSISA
CCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
ILMGVFILVVLIWLIDVVNLYHKYDDLQQFMEKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKTNILKKFTKALWPIELHEMKLFMPMALIIFCLLFNFSALRAIKDSLVVPSVGAEVIS
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FLKLWLVLPSAIIFTLTYVKLSNSYSMENIFYIIVTFFLIFFLLFAFIVYPNEMLLHPSE
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHH
ELIKEAIYNYPHLQWIIRICGKWSYAVMYIICELWSVVVINLMYWQFANNMFNIKDAKRF
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YPALGMIGNLGLIVAGNVLIACANNSEISIASDIFVINSDCAKNSEAIFKHIVIVVTIFG
HHHHHHHHCCHHEEECCEEEEECCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
IIAILTFKYLNNLVLGKAVIMHNKDNLMNNLKLYNHGTTKLSLKDSIKLILRSDYISRIA
HHHHHHHHHHHHHHHHHHHEEECCHHHHHCCEEEECCCCEEEHHHHHHHHHHHHHHHHHH
IMVICYGLSINILEGPWKAQIKELYPTTQEYITFMGKFNVVMGISCVMFMGMSSSILHKF
HHHHHHCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NWLFPALITPLIIGVTGIIFFLLIITGETASTIFSTVGYSPIYLAVLVGASQNILSKSSK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCC
CSLFDATKEIAYIPLDIETKIKGKAAVEVVGAKLGKSGGAFIQFLILTLYPESTISSISA
CCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
ILMGVFILVVLIWLIDVVNLYHKYDDLQQFMEKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]