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The map label for this gene is tlc [H]

Identifier: 148284166

GI number: 148284166

Start: 307658

End: 309190

Strand: Direct

Name: tlc [H]

Synonym: OTBS_0312

Alternate gene names: 148284166

Gene position: 307658-309190 (Clockwise)

Preceding gene: 148284165

Following gene: 148284167

Centisome position: 14.46

GC content: 28.44

Gene sequence:

>1533_bases
ATGAACTCTTACTATTTATTGTGCTATCTTCTTTCATGGGCTGCAATTAGAAGCTCTATGTCTTTTAATCTCAGTAAAAT
ATTTAATCATATATGGCCGGTACATCGATGTGAACTGCCAAGATTTTTACTGATGACTGCTTTAATGTTTTGCATACTTT
TGATTCAAAATTTAATTAGAGCTTTAAAAGATAGTATAGTAATTACTATGATTGGTGCTGAAACCACTTCTTTTTTAAAA
ATCTGGGGTGTATTACCAGCAGCATGCTTAATGACAATAATTTATATTAAATTAGTCAATGTTGTTAAGAATGAAAAAGT
ATTTTACATCATATTATTAACATTTTTAACATTTTTTTTTGTTTTTGGATTTATTATTTTTCCAAACTACCAATACTTAC
ATTTAAATGATCAAAGCATTCAAGCTCTAGTTTCTAAATTTCCACATTTTCGCTGGATTATCTTAATGTTGGCAAAATGG
AGCTTTTCACTTTTTTATATTATTTCTGAATTATGGCCTAATGCTGTTTTTGCGCTATTATACTGGCAATTTGTTAATAT
GGTAACTACAGTTGAGCAGTCAAGAAGATTTTATGTTTTATTTAGCTTATTTGGCCAAACTGGGTTATATATTTCTGGTA
CACTGATATCCTTTTTACCCTCAATGAGTAACTACTTTATTACTCATTATGATTTACAATGCAGTAAAACTACTGTTTAT
ATTCAAATTATAATATCTATTGTTTTACTACTAGGTAGTCTTTCTATGCTTATTTTTGCAATATTAAACGCTTACATAAT
TAAAATTGATGATGTGAGTTTTAAGTTTAAGTCTAATAAAATGTCAATATTAGATGGCATAAAAACAGCACTTGAATCTA
GATATATTAGGCTTATTATTACATTATTAATATGTTATGGCATAGCTATTAATTTAGTTGAAGCACCTTGGAAGTATAAA
GCTGCTACTTTATATCAAACCCCAGAAGAATATAATGCTTTTGTTGGTTCTTATTTAAGCTATACTGGTATTTGCACTAT
ACTGTTTGTTTTAGTCGGATCAAATATTGTGAGATATTTTGGGTGGAAAACAGCCGCAATGATTACTCCTATTATGTTAT
TTTCAACAGGTACAATATTCTTTATAACTTCAAGCTTTAATACTTCATTTCCTTTGTTTGAGCTAATCTGCCCTGCAATT
GATCCACTTAGTATAGCAATTACCACTGGAGCAACATTAAATATTTTAACCAAGTCTAGTAAATATACTTTCTTTGACTC
AACTAAAGAAATGGCATATGTTCCTCTTGATAATGAGTTAAAAAGTAAAGGCAAAGCTACAGCTGACGTAATGGGAATAA
AACTCGGTAAATCTGCTAGCGCATTAATTCAATCATTAACTTTTACACTTATTCCTACTGCTACTTACCAATCTATAACT
CCTTATTTAATGTTTATATTTATAATAATATGTATAGTATGGATGTGGGTAATTAGAGAATTAAACAAAGAATATTTAAA
GTTAATTAGCTAA

Upstream 100 bases:

>100_bases
ATTTGGTTGATAATAAATTTTATTATTTATCATAATTGACTTGAATAAATAAATTCATATGATAATAATTGCTAAGATTT
AATTCTTCAAACTATAAAGA

Downstream 100 bases:

>100_bases
TATGCACTAGATATACTTATTTACACCATTACTTTTATAGTTTAATACTATAAAACACCAATTTTAGTCGAATATATCTT
ATAATTTTGATTTTATTTGT

Product: ATP/ADP translocase

Products: NA

Alternate protein names: ADP/ATP translocase 4 [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MNSYYLLCYLLSWAAIRSSMSFNLSKIFNHIWPVHRCELPRFLLMTALMFCILLIQNLIRALKDSIVITMIGAETTSFLK
IWGVLPAACLMTIIYIKLVNVVKNEKVFYIILLTFLTFFFVFGFIIFPNYQYLHLNDQSIQALVSKFPHFRWIILMLAKW
SFSLFYIISELWPNAVFALLYWQFVNMVTTVEQSRRFYVLFSLFGQTGLYISGTLISFLPSMSNYFITHYDLQCSKTTVY
IQIIISIVLLLGSLSMLIFAILNAYIIKIDDVSFKFKSNKMSILDGIKTALESRYIRLIITLLICYGIAINLVEAPWKYK
AATLYQTPEEYNAFVGSYLSYTGICTILFVLVGSNIVRYFGWKTAAMITPIMLFSTGTIFFITSSFNTSFPLFELICPAI
DPLSIAITTGATLNILTKSSKYTFFDSTKEMAYVPLDNELKSKGKATADVMGIKLGKSASALIQSLTFTLIPTATYQSIT
PYLMFIFIIICIVWMWVIRELNKEYLKLIS

Sequences:

>Translated_510_residues
MNSYYLLCYLLSWAAIRSSMSFNLSKIFNHIWPVHRCELPRFLLMTALMFCILLIQNLIRALKDSIVITMIGAETTSFLK
IWGVLPAACLMTIIYIKLVNVVKNEKVFYIILLTFLTFFFVFGFIIFPNYQYLHLNDQSIQALVSKFPHFRWIILMLAKW
SFSLFYIISELWPNAVFALLYWQFVNMVTTVEQSRRFYVLFSLFGQTGLYISGTLISFLPSMSNYFITHYDLQCSKTTVY
IQIIISIVLLLGSLSMLIFAILNAYIIKIDDVSFKFKSNKMSILDGIKTALESRYIRLIITLLICYGIAINLVEAPWKYK
AATLYQTPEEYNAFVGSYLSYTGICTILFVLVGSNIVRYFGWKTAAMITPIMLFSTGTIFFITSSFNTSFPLFELICPAI
DPLSIAITTGATLNILTKSSKYTFFDSTKEMAYVPLDNELKSKGKATADVMGIKLGKSASALIQSLTFTLIPTATYQSIT
PYLMFIFIIICIVWMWVIRELNKEYLKLIS
>Mature_510_residues
MNSYYLLCYLLSWAAIRSSMSFNLSKIFNHIWPVHRCELPRFLLMTALMFCILLIQNLIRALKDSIVITMIGAETTSFLK
IWGVLPAACLMTIIYIKLVNVVKNEKVFYIILLTFLTFFFVFGFIIFPNYQYLHLNDQSIQALVSKFPHFRWIILMLAKW
SFSLFYIISELWPNAVFALLYWQFVNMVTTVEQSRRFYVLFSLFGQTGLYISGTLISFLPSMSNYFITHYDLQCSKTTVY
IQIIISIVLLLGSLSMLIFAILNAYIIKIDDVSFKFKSNKMSILDGIKTALESRYIRLIITLLICYGIAINLVEAPWKYK
AATLYQTPEEYNAFVGSYLSYTGICTILFVLVGSNIVRYFGWKTAAMITPIMLFSTGTIFFITSSFNTSFPLFELICPAI
DPLSIAITTGATLNILTKSSKYTFFDSTKEMAYVPLDNELKSKGKATADVMGIKLGKSASALIQSLTFTLIPTATYQSIT
PYLMFIFIIICIVWMWVIRELNKEYLKLIS

Specific function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism [H]

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004667 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58486; Mature: 58486

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSYYLLCYLLSWAAIRSSMSFNLSKIFNHIWPVHRCELPRFLLMTALMFCILLIQNLIR
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALKDSIVITMIGAETTSFLKIWGVLPAACLMTIIYIKLVNVVKNEKVFYIILLTFLTFFF
HHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VFGFIIFPNYQYLHLNDQSIQALVSKFPHFRWIILMLAKWSFSLFYIISELWPNAVFALL
HHHHHHCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWQFVNMVTTVEQSRRFYVLFSLFGQTGLYISGTLISFLPSMSNYFITHYDLQCSKTTVY
HHHHHHHHHHHHHCCCEEEEEEHHCCCCCEEHHHHHHHHHHHHCCEEEEEEEEECCHHHH
IQIIISIVLLLGSLSMLIFAILNAYIIKIDDVSFKFKSNKMSILDGIKTALESRYIRLII
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHH
TLLICYGIAINLVEAPWKYKAATLYQTPEEYNAFVGSYLSYTGICTILFVLVGSNIVRYF
HHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GWKTAAMITPIMLFSTGTIFFITSSFNTSFPLFELICPAIDPLSIAITTGATLNILTKSS
CCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCCCCCEEEEECCCEEEEEECCC
KYTFFDSTKEMAYVPLDNELKSKGKATADVMGIKLGKSASALIQSLTFTLIPTATYQSIT
CEEEEECCCCEEEECCCHHHHHCCCCHHHHHEEECCCHHHHHHHHHHHHHCCCCHHHHHH
PYLMFIFIIICIVWMWVIRELNKEYLKLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSYYLLCYLLSWAAIRSSMSFNLSKIFNHIWPVHRCELPRFLLMTALMFCILLIQNLIR
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALKDSIVITMIGAETTSFLKIWGVLPAACLMTIIYIKLVNVVKNEKVFYIILLTFLTFFF
HHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VFGFIIFPNYQYLHLNDQSIQALVSKFPHFRWIILMLAKWSFSLFYIISELWPNAVFALL
HHHHHHCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWQFVNMVTTVEQSRRFYVLFSLFGQTGLYISGTLISFLPSMSNYFITHYDLQCSKTTVY
HHHHHHHHHHHHHCCCEEEEEEHHCCCCCEEHHHHHHHHHHHHCCEEEEEEEEECCHHHH
IQIIISIVLLLGSLSMLIFAILNAYIIKIDDVSFKFKSNKMSILDGIKTALESRYIRLII
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHH
TLLICYGIAINLVEAPWKYKAATLYQTPEEYNAFVGSYLSYTGICTILFVLVGSNIVRYF
HHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GWKTAAMITPIMLFSTGTIFFITSSFNTSFPLFELICPAIDPLSIAITTGATLNILTKSS
CCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCCCCCEEEEECCCEEEEEECCC
KYTFFDSTKEMAYVPLDNELKSKGKATADVMGIKLGKSASALIQSLTFTLIPTATYQSIT
CEEEEECCCCEEEECCCHHHHHCCCCHHHHHEEECCCHHHHHHHHHHHHHCCCCHHHHHH
PYLMFIFIIICIVWMWVIRELNKEYLKLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA