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The map label for this gene is uxuA2 [H]

Identifier: 148260852

GI number: 148260852

Start: 2048972

End: 2050153

Strand: Reverse

Name: uxuA2 [H]

Synonym: Acry_1858

Alternate gene names: 148260852

Gene position: 2050153-2048972 (Counterclockwise)

Preceding gene: 148260853

Following gene: 148260851

Centisome position: 60.49

GC content: 72.93

Gene sequence:

>1182_bases
ATGGAAGAAACCTGGCGCTGGTTCGGGCCGGAAGATCCGATCCCGCTCGAGCATGTGCGGCAGGCGGGGGCGACCGGCGT
GGTGACGGCGCTGCACGACATTCCGCCCGGCGAGCCCTGGCCTGTCGCCGCGGCGCAGGCGCGGCGCGACGCGATCGAGG
CCGCCGGGCTGCGCTGGAGCGTGTGCGAGTCGATCCCGGTGCCGACCGGTATCAAGTGCCGCGACCATGACTGGCCGCGT
CTCGTCGCGGTGTGGAAGGACTCGCTCGCCGCGGTGGCGCGGGCGGGGGTCGGCGTGATCTGCTACAATTTCATGCCGGT
GATCGACTGGACGCGCACCGAACTTGCCCACGAGATGCCGGACGGGGCGAAGGCGCTGCGCTTCGACATGGTGGATTTCA
TCGGCTACGACGTCTTCGTGCTGCGCCGCGCCGGGGCGGCGTCGTGCTATCCGGCGCCGCTGGTCGCGCAGGCGGAGGCG
CGGATGGCGGCGTGCGACGCGGCGGCGCTGGCGCGGCTGGAACGGACCATCATCGCCGGCCTGCCGGGCGGGGCGGCGGC
GCAGACGCGGGAGACCATCGCCGCCGAGATCGCCCGGTTCGACGGGCTGGACGACGCGGCGGTGCGCGCCAATCTGGTCG
ATTTCCTGCGCGAGGTGGTGCCGGTGGCCGAGGAACTCGGCGTGCGGCTCGCGATCCATCCCGACGATCCGCCGGTGAAG
CTGTTCGGCCTGCCGCGCGTGGTCTCGACGCTGGAGGATCTGGCGATGCTGTTCGAGGCGGTGCCCTCGCGAGCGAACGG
GCTGACGCTCTGCGCCGGGTCGCTCGGGTCGCGCGCGGATAACGACGTGCTGGCGATCGCCGAGACGTTCCGCAGCCGCA
TCCATTTCGCCCATCTGCGCAACGTGACGGTCGAGCCGGACGGGTCCTTCGTCGAGGCGCCGCATCTCGGCGGGCGGACC
GACATGGTGGCCCTGCTCGCCCTGCTGCTGCGCGAGGAACGCGAGGCGGCGGCGGCGGGGCGGCGGGCGTCGATCCCGCT
GCGGCCGGACCACGGGCATCTGCTCGCGGCCGATGCCGCCAGGCGCGTCAATCCCGGCTATTCCTATATCGGCCGGCTGC
GCGGGCTGGCGGAGCTGCGTGGCGTGATCCGCGCGCTCGAAGCCCTGGCGCCGGCGGCGTGA

Upstream 100 bases:

>100_bases
TGATCGCCGAGGAATGCGGCGCGATGGCGCGGCAGGGGCTGGCGGCACGGCTCGACGCGCTCTGCCGCGCGCCGGACTGA
CAAGGGGAAAGGGCAGGGCG

Downstream 100 bases:

>100_bases
TGTTCGCCGCCATCGGGGAATGCCTCGCGGAGTTCGCGCCGAACGAAGCGGGCGGCTACGCGCTCGGTTTCGCGGGCGAT
ACGTTCAACGCCGCCTGGGC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase 2 [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MEETWRWFGPEDPIPLEHVRQAGATGVVTALHDIPPGEPWPVAAAQARRDAIEAAGLRWSVCESIPVPTGIKCRDHDWPR
LVAVWKDSLAAVARAGVGVICYNFMPVIDWTRTELAHEMPDGAKALRFDMVDFIGYDVFVLRRAGAASCYPAPLVAQAEA
RMAACDAAALARLERTIIAGLPGGAAAQTRETIAAEIARFDGLDDAAVRANLVDFLREVVPVAEELGVRLAIHPDDPPVK
LFGLPRVVSTLEDLAMLFEAVPSRANGLTLCAGSLGSRADNDVLAIAETFRSRIHFAHLRNVTVEPDGSFVEAPHLGGRT
DMVALLALLLREEREAAAAGRRASIPLRPDHGHLLAADAARRVNPGYSYIGRLRGLAELRGVIRALEALAPAA

Sequences:

>Translated_393_residues
MEETWRWFGPEDPIPLEHVRQAGATGVVTALHDIPPGEPWPVAAAQARRDAIEAAGLRWSVCESIPVPTGIKCRDHDWPR
LVAVWKDSLAAVARAGVGVICYNFMPVIDWTRTELAHEMPDGAKALRFDMVDFIGYDVFVLRRAGAASCYPAPLVAQAEA
RMAACDAAALARLERTIIAGLPGGAAAQTRETIAAEIARFDGLDDAAVRANLVDFLREVVPVAEELGVRLAIHPDDPPVK
LFGLPRVVSTLEDLAMLFEAVPSRANGLTLCAGSLGSRADNDVLAIAETFRSRIHFAHLRNVTVEPDGSFVEAPHLGGRT
DMVALLALLLREEREAAAAGRRASIPLRPDHGHLLAADAARRVNPGYSYIGRLRGLAELRGVIRALEALAPAA
>Mature_393_residues
MEETWRWFGPEDPIPLEHVRQAGATGVVTALHDIPPGEPWPVAAAQARRDAIEAAGLRWSVCESIPVPTGIKCRDHDWPR
LVAVWKDSLAAVARAGVGVICYNFMPVIDWTRTELAHEMPDGAKALRFDMVDFIGYDVFVLRRAGAASCYPAPLVAQAEA
RMAACDAAALARLERTIIAGLPGGAAAQTRETIAAEIARFDGLDDAAVRANLVDFLREVVPVAEELGVRLAIHPDDPPVK
LFGLPRVVSTLEDLAMLFEAVPSRANGLTLCAGSLGSRADNDVLAIAETFRSRIHFAHLRNVTVEPDGSFVEAPHLGGRT
DMVALLALLLREEREAAAAGRRASIPLRPDHGHLLAADAARRVNPGYSYIGRLRGLAELRGVIRALEALAPAA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=388, Percent_Identity=47.680412371134, Blast_Score=393, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 42281; Mature: 42281

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEETWRWFGPEDPIPLEHVRQAGATGVVTALHDIPPGEPWPVAAAQARRDAIEAAGLRWS
CCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHH
VCESIPVPTGIKCRDHDWPRLVAVWKDSLAAVARAGVGVICYNFMPVIDWTRTELAHEMP
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCHHHHHHHHHCC
DGAKALRFDMVDFIGYDVFVLRRAGAASCYPAPLVAQAEARMAACDAAALARLERTIIAG
CCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPGGAAAQTRETIAAEIARFDGLDDAAVRANLVDFLREVVPVAEELGVRLAIHPDDPPVK
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
LFGLPRVVSTLEDLAMLFEAVPSRANGLTLCAGSLGSRADNDVLAIAETFRSRIHFAHLR
EEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHC
NVTVEPDGSFVEAPHLGGRTDMVALLALLLREEREAAAAGRRASIPLRPDHGHLLAADAA
CCEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCHH
RRVNPGYSYIGRLRGLAELRGVIRALEALAPAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEETWRWFGPEDPIPLEHVRQAGATGVVTALHDIPPGEPWPVAAAQARRDAIEAAGLRWS
CCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHH
VCESIPVPTGIKCRDHDWPRLVAVWKDSLAAVARAGVGVICYNFMPVIDWTRTELAHEMP
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCHHHHHHHHHCC
DGAKALRFDMVDFIGYDVFVLRRAGAASCYPAPLVAQAEARMAACDAAALARLERTIIAG
CCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPGGAAAQTRETIAAEIARFDGLDDAAVRANLVDFLREVVPVAEELGVRLAIHPDDPPVK
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
LFGLPRVVSTLEDLAMLFEAVPSRANGLTLCAGSLGSRADNDVLAIAETFRSRIHFAHLR
EEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHC
NVTVEPDGSFVEAPHLGGRTDMVALLALLLREEREAAAAGRRASIPLRPDHGHLLAADAA
CCEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCHH
RRVNPGYSYIGRLRGLAELRGVIRALEALAPAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]