Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 148260657

GI number: 148260657

Start: 1831044

End: 1832534

Strand: Reverse

Name: xylB [H]

Synonym: Acry_1660

Alternate gene names: 148260657

Gene position: 1832534-1831044 (Counterclockwise)

Preceding gene: 148260658

Following gene: 148260656

Centisome position: 54.07

GC content: 73.84

Gene sequence:

>1491_bases
GTGGAGGCCGTGATCGGGCTTGACTGCAGCACCAGCGCGGTCAAGGCGCTGGCCTTCGACCGGCAGGGAAGCGTGCTGGC
CATCGGCCGTGCCCGGCTCCCCTTCGCGCCCGATGCCGAAGGCCGGTTCGAGCAGGACCCGGAATACTGGTGGCGGGCCT
GCCGCGCGGCGCTCGCCGAACTGGCCGCGGGGCTCGACGGGATCGAGATCGCCGGGCTGGCGATCGCCAACCAGCGCGAG
ACGATCGCGCCGCTCGATGCCGGTTTCCGGCCGGTTCGGCCGGCGATCCTGTGGCTCGACGGGCGGGCGGCGGGCGATGC
CGCGGCGATGGCGGAGGCCCTCGGCGCCGACCATCTGCACCGGGTTACCGGCAAGATCCCCGACCCCAATCCGGCGCTTT
ACAAGCTGGCCTGGATGCGCCGCTGCGAGCCGGAGCGGCTCGGCGCCAGCGCCTGGTTCGCCGAGGTGCATGGCTATCTG
GTCCAGCGGCTGACGGGCCGGTTCGCGACCAGCACCGCATCGGCCGATCCGCTCGGCGTCTATGATCTCGCGGCGAAGCG
CTACGCGGACGACCTGCTCGACGCGATCGGGCTGTCCGCCGCGCGGTTCGCGCCGGCGCTGCCGCCCGGCACGAAGCTGG
GCGGCCTGACCGCCGAGGCCGCGCGCGCGACCGGCCTGCAAGAAGGGCTGAAGGTGATTGCCGGCGCCGGCGACGGCCAG
GCGGCCGGTCTCGGCGTGAACGTGATGGAGCCGGGCCGGGCCTATCTCAACCTCGGCACCGCCGTGGTCGCCGGAATGCG
GAGCGCGAGCTACCGGGTGGGGCGCGGCTTCCGCACCATGATCGCCGCGGATGGCGAGGGCTATATCCTCGAAACCTCGC
TCCGTTCGGGCACGTTGCTGTGCGACTGGCTGACGCGCGACATCCTCGGCGGCGATGCAGCACTGCTCGCCGAGCTCGAA
CCCGCGGCGGCGGCGCTGCCGCCGGGATCGGACGGGGTGATGATCCTGCCCTATTTCCTCGGGGTGATGACGCCGCACTG
GGACGGCGCCGCGCGCGGCGCGATCGTCGGGCTCGCGCCGCATCACGGCAGGGCGCATCTCCTGCGGGCGCTGTACGAAG
GCATCGCCCTGGAGCAGGCCGGGGTGATGGCGCGCATCGAGGCCGAGGCCGGGCTCGCCGCGCGCGAGATCGTCGCCATC
GGCGGCGGCGCGCAAAGCGACCTCTGGTGCGCGATCCTGGCCGACGCGCATGGCGTGCCGGTGCTGAGATCGGCGACGGT
CGAGGCCACCAGCCTTGGCGCGGCGATGGCCGCCGCCGTCGGCGCGGGCTGGTATTCCGGATTTGCCGAGGCCGCATCGG
CGATGGCCGGCGCGGTGACCGCGCGCTTCACCCCGGATGCAGGCCGCGCCGCCCTCTATGCCCGCCTGCGCCGCGCCCAT
GCCGGGCTCTATCCGGCGCTGCGGCCGTTCGGCGCCGCCCCGTTGACCTGA

Upstream 100 bases:

>100_bases
GTGGCGGACAACGACGACGACGCGGCGCGTGGCGCGTCCCGCAGGGTGGCGAAGGCGTGACGCGCCGGCGATTCGCGCGC
GCGAGACAGGGAGAACCGCC

Downstream 100 bases:

>100_bases
AAGGATACCACGATGAAGGCTCTCTACATCCGCGGCGTGCGGGACATCACGATCGGCGATGCGCCCGAACCCGTGCCGGG
AAACGACCGCATTGCCGTCG

Product: carbohydrate kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MEAVIGLDCSTSAVKALAFDRQGSVLAIGRARLPFAPDAEGRFEQDPEYWWRACRAALAELAAGLDGIEIAGLAIANQRE
TIAPLDAGFRPVRPAILWLDGRAAGDAAAMAEALGADHLHRVTGKIPDPNPALYKLAWMRRCEPERLGASAWFAEVHGYL
VQRLTGRFATSTASADPLGVYDLAAKRYADDLLDAIGLSAARFAPALPPGTKLGGLTAEAARATGLQEGLKVIAGAGDGQ
AAGLGVNVMEPGRAYLNLGTAVVAGMRSASYRVGRGFRTMIAADGEGYILETSLRSGTLLCDWLTRDILGGDAALLAELE
PAAAALPPGSDGVMILPYFLGVMTPHWDGAARGAIVGLAPHHGRAHLLRALYEGIALEQAGVMARIEAEAGLAAREIVAI
GGGAQSDLWCAILADAHGVPVLRSATVEATSLGAAMAAAVGAGWYSGFAEAASAMAGAVTARFTPDAGRAALYARLRRAH
AGLYPALRPFGAAPLT

Sequences:

>Translated_496_residues
MEAVIGLDCSTSAVKALAFDRQGSVLAIGRARLPFAPDAEGRFEQDPEYWWRACRAALAELAAGLDGIEIAGLAIANQRE
TIAPLDAGFRPVRPAILWLDGRAAGDAAAMAEALGADHLHRVTGKIPDPNPALYKLAWMRRCEPERLGASAWFAEVHGYL
VQRLTGRFATSTASADPLGVYDLAAKRYADDLLDAIGLSAARFAPALPPGTKLGGLTAEAARATGLQEGLKVIAGAGDGQ
AAGLGVNVMEPGRAYLNLGTAVVAGMRSASYRVGRGFRTMIAADGEGYILETSLRSGTLLCDWLTRDILGGDAALLAELE
PAAAALPPGSDGVMILPYFLGVMTPHWDGAARGAIVGLAPHHGRAHLLRALYEGIALEQAGVMARIEAEAGLAAREIVAI
GGGAQSDLWCAILADAHGVPVLRSATVEATSLGAAMAAAVGAGWYSGFAEAASAMAGAVTARFTPDAGRAALYARLRRAH
AGLYPALRPFGAAPLT
>Mature_496_residues
MEAVIGLDCSTSAVKALAFDRQGSVLAIGRARLPFAPDAEGRFEQDPEYWWRACRAALAELAAGLDGIEIAGLAIANQRE
TIAPLDAGFRPVRPAILWLDGRAAGDAAAMAEALGADHLHRVTGKIPDPNPALYKLAWMRRCEPERLGASAWFAEVHGYL
VQRLTGRFATSTASADPLGVYDLAAKRYADDLLDAIGLSAARFAPALPPGTKLGGLTAEAARATGLQEGLKVIAGAGDGQ
AAGLGVNVMEPGRAYLNLGTAVVAGMRSASYRVGRGFRTMIAADGEGYILETSLRSGTLLCDWLTRDILGGDAALLAELE
PAAAALPPGSDGVMILPYFLGVMTPHWDGAARGAIVGLAPHHGRAHLLRALYEGIALEQAGVMARIEAEAGLAAREIVAI
GGGAQSDLWCAILADAHGVPVLRSATVEATSLGAAMAAAVGAGWYSGFAEAASAMAGAVTARFTPDAGRAALYARLRRAH
AGLYPALRPFGAAPLT

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=515, Percent_Identity=26.4077669902913, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI88196792, Length=490, Percent_Identity=23.265306122449, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI41393575, Length=460, Percent_Identity=23.0434782608696, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI42794763, Length=462, Percent_Identity=22.2943722943723, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4504007, Length=460, Percent_Identity=22.1739130434783, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI189409120, Length=460, Percent_Identity=22.1739130434783, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI164663830, Length=538, Percent_Identity=25.6505576208178, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789987, Length=493, Percent_Identity=31.4401622718053, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1790005, Length=508, Percent_Identity=28.5433070866142, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787789, Length=509, Percent_Identity=29.0766208251473, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789138, Length=495, Percent_Identity=25.6565656565657, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789168, Length=508, Percent_Identity=25.9842519685039, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790361, Length=463, Percent_Identity=26.133909287257, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17535599, Length=514, Percent_Identity=25.4863813229572, Blast_Score=99, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6321755, Length=447, Percent_Identity=23.7136465324385, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864214, Length=474, Percent_Identity=24.6835443037975, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24654573, Length=402, Percent_Identity=25.1243781094527, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24655555, Length=450, Percent_Identity=24.8888888888889, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655560, Length=450, Percent_Identity=24.8888888888889, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655570, Length=450, Percent_Identity=24.8888888888889, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655574, Length=450, Percent_Identity=24.8888888888889, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655565, Length=450, Percent_Identity=24.8888888888889, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51270; Mature: 51270

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVIGLDCSTSAVKALAFDRQGSVLAIGRARLPFAPDAEGRFEQDPEYWWRACRAALAE
CCCEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LAAGLDGIEIAGLAIANQRETIAPLDAGFRPVRPAILWLDGRAAGDAAAMAEALGADHLH
HHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHH
RVTGKIPDPNPALYKLAWMRRCEPERLGASAWFAEVHGYLVQRLTGRFATSTASADPLGV
HHHCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCH
YDLAAKRYADDLLDAIGLSAARFAPALPPGTKLGGLTAEAARATGLQEGLKVIAGAGDGQ
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCC
AAGLGVNVMEPGRAYLNLGTAVVAGMRSASYRVGRGFRTMIAADGEGYILETSLRSGTLL
CCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCEEEEECCCCCCEE
CDWLTRDILGGDAALLAELEPAAAALPPGSDGVMILPYFLGVMTPHWDGAARGAIVGLAP
HHHHHHHHCCCCHHEEEECCCHHHCCCCCCCCEEEHHHHHHHCCCCCCCCCCCEEEEECC
HHGRAHLLRALYEGIALEQAGVMARIEAEAGLAAREIVAIGGGAQSDLWCAILADAHGVP
CCCHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCEEEEEEECCCCCCCEEEEEEECCCCCC
VLRSATVEATSLGAAMAAAVGAGWYSGFAEAASAMAGAVTARFTPDAGRAALYARLRRAH
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
AGLYPALRPFGAAPLT
CCCCHHHCCCCCCCCC
>Mature Secondary Structure
MEAVIGLDCSTSAVKALAFDRQGSVLAIGRARLPFAPDAEGRFEQDPEYWWRACRAALAE
CCCEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LAAGLDGIEIAGLAIANQRETIAPLDAGFRPVRPAILWLDGRAAGDAAAMAEALGADHLH
HHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHH
RVTGKIPDPNPALYKLAWMRRCEPERLGASAWFAEVHGYLVQRLTGRFATSTASADPLGV
HHHCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCH
YDLAAKRYADDLLDAIGLSAARFAPALPPGTKLGGLTAEAARATGLQEGLKVIAGAGDGQ
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCC
AAGLGVNVMEPGRAYLNLGTAVVAGMRSASYRVGRGFRTMIAADGEGYILETSLRSGTLL
CCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCEEEEECCCCCCEE
CDWLTRDILGGDAALLAELEPAAAALPPGSDGVMILPYFLGVMTPHWDGAARGAIVGLAP
HHHHHHHHCCCCHHEEEECCCHHHCCCCCCCCEEEHHHHHHHCCCCCCCCCCCEEEEECC
HHGRAHLLRALYEGIALEQAGVMARIEAEAGLAAREIVAIGGGAQSDLWCAILADAHGVP
CCCHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCEEEEEEECCCCCCCEEEEEEECCCCCC
VLRSATVEATSLGAAMAAAVGAGWYSGFAEAASAMAGAVTARFTPDAGRAALYARLRRAH
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
AGLYPALRPFGAAPLT
CCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]