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The map label for this gene is aatC [H]

Identifier: 148260302

GI number: 148260302

Start: 1452492

End: 1453703

Strand: Reverse

Name: aatC [H]

Synonym: Acry_1299

Alternate gene names: 148260302

Gene position: 1453703-1452492 (Counterclockwise)

Preceding gene: 148260303

Following gene: 148260301

Centisome position: 42.89

GC content: 66.91

Gene sequence:

>1212_bases
ATGACCGAGGAATTTCACCGCATCCGCCGCCTTCCACCCTATGTCTTCGCGGAGGTGAACCAGGCGAAGGCGGCCGCGCG
CAACCGGCGCGAGGACATCATCGACCTCGGCATGGGCAATCCCGACAGCGCGACGCCGCCGCATATCGTGGCCAAGCTGG
TCGAGACCGTGGCCGACCCGCGCAGCCACCGCTATTCCACCAGCAAGGGCATTCCCGGCCTGCGGCGCGCGCTTGCCGCG
TATTACGACCGCCGCTTCGGCGTGAAGCTGAACCCGGAGACCGAGGTGATCGCCACACTCGGCTCGAAGGAGGGGCTGGC
CAACCTCGCCAACGCGATCACCTCGCCGGGCGACACGATCCTGGTGCCCAACCCGTCCTACCCGATCCACCAGTTCGGCT
TCATCATCGCCGGGGCCTCGGTGCGCTCGGTGCCGGCCACGCCGGATGACGAGATGCTGCGCGCGCTCGACCGTGCGGTG
CGGCACTCGGTGCCGAAGCCGACCGCGCTGATCGTGAATTTTCCTTCAAATCCAACGGCATATCTGGCGACCCTGGATTT
CTACAAGGAAATCGTCGCGTTCGCCCGCAAGCACGAGATCTTCATCCTGTCCGATCTCGCCTATGCCGAGATCTATTTCG
AGGGCGAGCCGCCGCCCTCGGTGCTGCAGGTCGAGGGGGCGAAGGACATCACGGTGGAATTCACCTCGATGTCGAAGACC
TATTCGATGCCGGGCTGGCGCATGGGCTTCGCCGCCGGCAATCCGCGGCTGGTCGCGGCGCTCGCGCGCATGAAGTCCTA
TCTCGACTACGGCGCCTTCACGCCGATCCAGGTCGCGGCGACGGCGGCGCTGAACGGGCCGCAGGACTGCGTCGAGCAGA
TGCGCACGCTCTACCGCGAACGGCGCGACGTGCTGATCAAGGGACTCGCGCAGGCAGGCTGGGACGTGCCGAGCCCGGCG
GGGTCGATGTTCGCCTGGGCGCCGATTCCGGAGCGCTTCGCGCATCTCGGCTCGGTCGATTTCGCGAAGCTGCTGCTGGA
GCGCGCCAAGGTCGCGGTCGCGCCGGGGATCGGCTTCGGCGAGTATGGCGATGGCCATGTCCGCATCGCGCTCGTCGAAA
ATACCCATCGGCTCCGGCAGGCGGTGCGGAACATCCGCGCCTTCATGGCACCGGGCAATGCGCCCAACCAGCAGGAGAGC
GTCTCGGCATGA

Upstream 100 bases:

>100_bases
CAGACATTCGCCTCGAAGCGCTCGCCAGCGGTCGCGGCGGTGCGGCACAGATGTTATACCCCCGCCACAAACCCACCACA
CCGGACGCTCAGGACCGATC

Downstream 100 bases:

>100_bases
ATGGTGAACTGTCGGTCGGGATCGCCGGGCTGGGGACGGTCGGCGCCGGGGTCGTGCGGCTGTTGCAGGAGAATGCGGCG
ATCATCGCCGCGCGGGCCGG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTEEFHRIRRLPPYVFAEVNQAKAAARNRREDIIDLGMGNPDSATPPHIVAKLVETVADPRSHRYSTSKGIPGLRRALAA
YYDRRFGVKLNPETEVIATLGSKEGLANLANAITSPGDTILVPNPSYPIHQFGFIIAGASVRSVPATPDDEMLRALDRAV
RHSVPKPTALIVNFPSNPTAYLATLDFYKEIVAFARKHEIFILSDLAYAEIYFEGEPPPSVLQVEGAKDITVEFTSMSKT
YSMPGWRMGFAAGNPRLVAALARMKSYLDYGAFTPIQVAATAALNGPQDCVEQMRTLYRERRDVLIKGLAQAGWDVPSPA
GSMFAWAPIPERFAHLGSVDFAKLLLERAKVAVAPGIGFGEYGDGHVRIALVENTHRLRQAVRNIRAFMAPGNAPNQQES
VSA

Sequences:

>Translated_403_residues
MTEEFHRIRRLPPYVFAEVNQAKAAARNRREDIIDLGMGNPDSATPPHIVAKLVETVADPRSHRYSTSKGIPGLRRALAA
YYDRRFGVKLNPETEVIATLGSKEGLANLANAITSPGDTILVPNPSYPIHQFGFIIAGASVRSVPATPDDEMLRALDRAV
RHSVPKPTALIVNFPSNPTAYLATLDFYKEIVAFARKHEIFILSDLAYAEIYFEGEPPPSVLQVEGAKDITVEFTSMSKT
YSMPGWRMGFAAGNPRLVAALARMKSYLDYGAFTPIQVAATAALNGPQDCVEQMRTLYRERRDVLIKGLAQAGWDVPSPA
GSMFAWAPIPERFAHLGSVDFAKLLLERAKVAVAPGIGFGEYGDGHVRIALVENTHRLRQAVRNIRAFMAPGNAPNQQES
VSA
>Mature_402_residues
TEEFHRIRRLPPYVFAEVNQAKAAARNRREDIIDLGMGNPDSATPPHIVAKLVETVADPRSHRYSTSKGIPGLRRALAAY
YDRRFGVKLNPETEVIATLGSKEGLANLANAITSPGDTILVPNPSYPIHQFGFIIAGASVRSVPATPDDEMLRALDRAVR
HSVPKPTALIVNFPSNPTAYLATLDFYKEIVAFARKHEIFILSDLAYAEIYFEGEPPPSVLQVEGAKDITVEFTSMSKTY
SMPGWRMGFAAGNPRLVAALARMKSYLDYGAFTPIQVAATAALNGPQDCVEQMRTLYRERRDVLIKGLAQAGWDVPSPAG
SMFAWAPIPERFAHLGSVDFAKLLLERAKVAVAPGIGFGEYGDGHVRIALVENTHRLRQAVRNIRAFMAPGNAPNQQESV
SA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=412, Percent_Identity=22.0873786407767, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI56713254, Length=386, Percent_Identity=22.020725388601, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=20.8651399491094, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=20.8651399491094, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI215599424, Length=379, Percent_Identity=25.065963060686, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19263340, Length=379, Percent_Identity=25.065963060686, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=22.680412371134, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4885351, Length=383, Percent_Identity=24.5430809399478, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=55.7788944723618, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1786816, Length=333, Percent_Identity=24.9249249249249, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788627, Length=389, Percent_Identity=24.1645244215938, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787710, Length=297, Percent_Identity=24.9158249158249, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=24.1463414634146, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=366, Percent_Identity=23.4972677595628, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=366, Percent_Identity=23.4972677595628, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=407, Percent_Identity=23.3415233415233, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=22.7390180878553, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=22.5352112676056, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323118, Length=352, Percent_Identity=23.2954545454545, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573069, Length=316, Percent_Identity=25.9493670886076, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24646114, Length=316, Percent_Identity=25.9493670886076, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28573067, Length=316, Percent_Identity=25.9493670886076, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28573065, Length=316, Percent_Identity=25.9493670886076, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24641770, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641760, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641768, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641766, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641764, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45551451, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859735, Length=375, Percent_Identity=23.2, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44139; Mature: 44008

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEFHRIRRLPPYVFAEVNQAKAAARNRREDIIDLGMGNPDSATPPHIVAKLVETVADP
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
RSHRYSTSKGIPGLRRALAAYYDRRFGVKLNPETEVIATLGSKEGLANLANAITSPGDTI
HHCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCHHEEEECCCCCHHHHHHHHHCCCCCEE
LVPNPSYPIHQFGFIIAGASVRSVPATPDDEMLRALDRAVRHSVPKPTALIVNFPSNPTA
EECCCCCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCE
YLATLDFYKEIVAFARKHEIFILSDLAYAEIYFEGEPPPSVLQVEGAKDITVEFTSMSKT
EHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCEEEECCCCEEEEEEECCCCC
YSMPGWRMGFAAGNPRLVAALARMKSYLDYGAFTPIQVAATAALNGPQDCVEQMRTLYRE
CCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDVLIKGLAQAGWDVPSPAGSMFAWAPIPERFAHLGSVDFAKLLLERAKVAVAPGIGFG
HHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHCCCHHHHHHHHHHHHEEECCCCCCC
EYGDGHVRIALVENTHRLRQAVRNIRAFMAPGNAPNQQESVSA
CCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure 
TEEFHRIRRLPPYVFAEVNQAKAAARNRREDIIDLGMGNPDSATPPHIVAKLVETVADP
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
RSHRYSTSKGIPGLRRALAAYYDRRFGVKLNPETEVIATLGSKEGLANLANAITSPGDTI
HHCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCHHEEEECCCCCHHHHHHHHHCCCCCEE
LVPNPSYPIHQFGFIIAGASVRSVPATPDDEMLRALDRAVRHSVPKPTALIVNFPSNPTA
EECCCCCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCE
YLATLDFYKEIVAFARKHEIFILSDLAYAEIYFEGEPPPSVLQVEGAKDITVEFTSMSKT
EHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCEEEECCCCEEEEEEECCCCC
YSMPGWRMGFAAGNPRLVAALARMKSYLDYGAFTPIQVAATAALNGPQDCVEQMRTLYRE
CCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDVLIKGLAQAGWDVPSPAGSMFAWAPIPERFAHLGSVDFAKLLLERAKVAVAPGIGFG
HHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHCCCHHHHHHHHHHHHEEECCCCCCC
EYGDGHVRIALVENTHRLRQAVRNIRAFMAPGNAPNQQESVSA
CCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]