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The map label for this gene is phhB

Identifier: 148259782

GI number: 148259782

Start: 862329

End: 862616

Strand: Reverse

Name: phhB

Synonym: Acry_0770

Alternate gene names: NA

Gene position: 862616-862329 (Counterclockwise)

Preceding gene: 148259783

Following gene: 148259781

Centisome position: 25.45

GC content: 65.62

Gene sequence:

>288_bases
ATGATCCCCCGCCTGACCGATGCCGAACGCGCCGCCCTTGTCGACCTCTTGCCGGAATGGTCGCTGGCGAAGGACCGCGA
CGCGATCGAACGGCGCTTCGCCTTCGCCGATTTCTCCGAGGCCTTCGCGTTCATGACGCGGGTGGCGCTGCTCGCGGAGA
AGCACGACCATCATCCGGAATGGTCGAATGTCTACAATCGCGTGACGATCCTGCTGTCGACCCATGACGCGGGGGGGCTT
TCGGCGCGCGATATCCGCCTCGCGGAGGCGATCGACGGGCTGGCTTGA

Upstream 100 bases:

>100_bases
CACGGGCCTGGGCGGCGCGGCGGCCCTGGTTCGAGACCGAGGTGATCCCCGCCCTGCGCGCCGCCTTCGCCGCCGCCCTC
TCGGAGCAAGGAGACACGAC

Downstream 100 bases:

>100_bases
GCGCCGCTGTCTTTTCCGGCACGCCGCCCTCCCCTATCGTCGTGCCGCCAACAGAGGGACATTCGATGAGCACCAGCAGG
ATCGACGACGTTCTCGCCCA

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MIPRLTDAERAALVDLLPEWSLAKDRDAIERRFAFADFSEAFAFMTRVALLAEKHDHHPEWSNVYNRVTILLSTHDAGGL
SARDIRLAEAIDGLA

Sequences:

>Translated_95_residues
MIPRLTDAERAALVDLLPEWSLAKDRDAIERRFAFADFSEAFAFMTRVALLAEKHDHHPEWSNVYNRVTILLSTHDAGGL
SARDIRLAEAIDGLA
>Mature_95_residues
MIPRLTDAERAALVDLLPEWSLAKDRDAIERRFAFADFSEAFAFMTRVALLAEKHDHHPEWSNVYNRVTILLSTHDAGGL
SARDIRLAEAIDGLA

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=94, Percent_Identity=56.3829787234042, Blast_Score=99, Evalue=5e-22,
Organism=Homo sapiens, GI134133240, Length=91, Percent_Identity=52.7472527472528, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI115533705, Length=96, Percent_Identity=55.2083333333333, Blast_Score=113, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45549100, Length=97, Percent_Identity=52.5773195876289, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_ACICJ (A5FWK8)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001233909.1
- ProteinModelPortal:   A5FWK8
- SMR:   A5FWK8
- STRING:   A5FWK8
- GeneID:   5160205
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_0770
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   IALICEK
- ProtClustDB:   PRK00823
- BioCyc:   ACRY349163:ACRY_0770-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 10690; Mature: 10690

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRLTDAERAALVDLLPEWSLAKDRDAIERRFAFADFSEAFAFMTRVALLAEKHDHHPE
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WSNVYNRVTILLSTHDAGGLSARDIRLAEAIDGLA
HHHHHHEEEEEEECCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MIPRLTDAERAALVDLLPEWSLAKDRDAIERRFAFADFSEAFAFMTRVALLAEKHDHHPE
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WSNVYNRVTILLSTHDAGGLSARDIRLAEAIDGLA
HHHHHHEEEEEEECCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA