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The map label for this gene is aatA [H]

Identifier: 148259752

GI number: 148259752

Start: 828392

End: 829594

Strand: Reverse

Name: aatA [H]

Synonym: Acry_0740

Alternate gene names: 148259752

Gene position: 829594-828392 (Counterclockwise)

Preceding gene: 148259755

Following gene: 148259751

Centisome position: 24.48

GC content: 66.17

Gene sequence:

>1203_bases
ATGAACCTGATCGCCGCACGCCTGAACCGGATCAGCCCGAGCCAGACGATCGCCATTTCGACCAAGGCGCGCCAGCTCAA
GGCCGAGGGCCGCGACATCATCAGCCTCTCCGCCGGCGAGCCTGATTTCGACACGCCGGACCACATCAAGCGCGCCGCCA
TCGCCGCGATAGAGGCGGGCGAGACCAAGTATACCGACGTCGCCGGCACCATGGCGCTGCGCAAGGCCGTTGCCGCGAAA
TTCAAGCGCGACAACGGGATCGACTACACGCCGCAGGAGATCATCGTCTCGACCGGCGGCAAGCAGGTCATCTTCAACGC
CATGCTCGCCACCGTCGAGGCCGGCGACGAGGTGATCATCCCGACACCGTGCTGGGTCAGCTATCCGGACATCGTCCAGC
TCGCCGAGGGCAAGCCGGTCTTCGTCCCCTGCAGCCAGAACAACGGCTTCAAGCTGCGCGCCGAGGATCTCGAGGCGGCG
ATCACGCCGAAGACCAAGTGGCTGATGCTGAACTCGCCTTCGAACCCGACCGGGGCGGCCTATTCGGCGGAAGACCTCCG
CCCGATCTGCGACGTGCTGCTGCGCCACCCCGACATCTGGGTGTTCACCGACGACATCTACGAGAAGCTCGTCTATGACG
GCTTTGCTCCGGCCACCATCGTCGGCGTCGAGCCGAAGCTGCGCGAGCGCACGGTGACGATGAACGGCTGCTCCAAGGCC
TATGCGATGACCGGCTGGCGAATCGGCTTCTGCGGCGCGCCGGTCCAGCTTATCAAGGCGATGGACAAGCTGCAGAGCCA
GTCGACCTCGAACACCTCCTCGGTGAGCCAGGTCGCGGCCCTCGCCGCGCTGGAAGGCCCGGAGGACGCGATCGACGTGA
TGCGCGCCGCCTATCGCGAGCGGCGGGATCTCGTGGTCGCGATGCTCAACGAGGCCCCGGGCATCACCTGCTCGAAGCCC
GAGGGCGCGTTCTACGTCTTCCCCTCGATCGCCGGCTGCCTCGGCAAGACCTCGGCGGGCGGAACAAAAATCGTCGATGA
CGAGGCCTTTGTCACGGCGCTGCTGGAAGAGCAGGGAGTCGCGGCCGTGCATGGCAGCGCCTTCATCTATCCCGGCTATT
TCCGGGTCAGCTACGCGACCTCGACCGAGGCGCTGCGCGACGCCTGCACCCGCATCCAGACCTTCTGCCAGGGGCTGCGC
TGA

Upstream 100 bases:

>100_bases
CCCGTCATGAGCGGAGTTCGTGCCGGCCCGCGCATCAGGGCCATGTTCATCGCGCGGCAGTTCGGTTACATCGGGGCCGT
TGTCACGGGGAGCATCGCAC

Downstream 100 bases:

>100_bases
ACCGCGGCTTCCGCCTCTCCCGACCGCCCCACGGTTTTTCAGGCCCGCGCGATGCAGATCGCGCGGGCCTTTGCGTCGAT
TCGGCATTGTGCGGCCACCC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNLIAARLNRISPSQTIAISTKARQLKAEGRDIISLSAGEPDFDTPDHIKRAAIAAIEAGETKYTDVAGTMALRKAVAAK
FKRDNGIDYTPQEIIVSTGGKQVIFNAMLATVEAGDEVIIPTPCWVSYPDIVQLAEGKPVFVPCSQNNGFKLRAEDLEAA
ITPKTKWLMLNSPSNPTGAAYSAEDLRPICDVLLRHPDIWVFTDDIYEKLVYDGFAPATIVGVEPKLRERTVTMNGCSKA
YAMTGWRIGFCGAPVQLIKAMDKLQSQSTSNTSSVSQVAALAALEGPEDAIDVMRAAYRERRDLVVAMLNEAPGITCSKP
EGAFYVFPSIAGCLGKTSAGGTKIVDDEAFVTALLEEQGVAAVHGSAFIYPGYFRVSYATSTEALRDACTRIQTFCQGLR

Sequences:

>Translated_400_residues
MNLIAARLNRISPSQTIAISTKARQLKAEGRDIISLSAGEPDFDTPDHIKRAAIAAIEAGETKYTDVAGTMALRKAVAAK
FKRDNGIDYTPQEIIVSTGGKQVIFNAMLATVEAGDEVIIPTPCWVSYPDIVQLAEGKPVFVPCSQNNGFKLRAEDLEAA
ITPKTKWLMLNSPSNPTGAAYSAEDLRPICDVLLRHPDIWVFTDDIYEKLVYDGFAPATIVGVEPKLRERTVTMNGCSKA
YAMTGWRIGFCGAPVQLIKAMDKLQSQSTSNTSSVSQVAALAALEGPEDAIDVMRAAYRERRDLVVAMLNEAPGITCSKP
EGAFYVFPSIAGCLGKTSAGGTKIVDDEAFVTALLEEQGVAAVHGSAFIYPGYFRVSYATSTEALRDACTRIQTFCQGLR
>Mature_400_residues
MNLIAARLNRISPSQTIAISTKARQLKAEGRDIISLSAGEPDFDTPDHIKRAAIAAIEAGETKYTDVAGTMALRKAVAAK
FKRDNGIDYTPQEIIVSTGGKQVIFNAMLATVEAGDEVIIPTPCWVSYPDIVQLAEGKPVFVPCSQNNGFKLRAEDLEAA
ITPKTKWLMLNSPSNPTGAAYSAEDLRPICDVLLRHPDIWVFTDDIYEKLVYDGFAPATIVGVEPKLRERTVTMNGCSKA
YAMTGWRIGFCGAPVQLIKAMDKLQSQSTSNTSSVSQVAALAALEGPEDAIDVMRAAYRERRDLVVAMLNEAPGITCSKP
EGAFYVFPSIAGCLGKTSAGGTKIVDDEAFVTALLEEQGVAAVHGSAFIYPGYFRVSYATSTEALRDACTRIQTFCQGLR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=407, Percent_Identity=28.009828009828, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI56713256, Length=357, Percent_Identity=28.8515406162465, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI95147551, Length=363, Percent_Identity=28.6501377410468, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881279, Length=363, Percent_Identity=28.6501377410468, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881281, Length=360, Percent_Identity=25.2777777777778, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=21.5025906735751, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19263340, Length=372, Percent_Identity=22.8494623655914, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=22.8494623655914, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4885351, Length=367, Percent_Identity=24.5231607629428, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=29.5165394402036, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=29.2225201072386, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1788722, Length=332, Percent_Identity=32.2289156626506, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1790797, Length=304, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787710, Length=214, Percent_Identity=28.0373831775701, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=24.2744063324538, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=385, Percent_Identity=25.7142857142857, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=385, Percent_Identity=25.7142857142857, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=364, Percent_Identity=25.2747252747253, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71981209, Length=371, Percent_Identity=23.4501347708895, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=317, Percent_Identity=26.1829652996845, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320317, Length=347, Percent_Identity=24.207492795389, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=356, Percent_Identity=25.561797752809, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646114, Length=356, Percent_Identity=25.561797752809, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573067, Length=356, Percent_Identity=25.561797752809, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573065, Length=356, Percent_Identity=25.561797752809, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=24.4791666666667, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641770, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641760, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641768, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641766, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641764, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45551451, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43147; Mature: 43147

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIAARLNRISPSQTIAISTKARQLKAEGRDIISLSAGEPDFDTPDHIKRAAIAAIEAG
CCCHHHHHHCCCCCCEEEEEHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHEECC
ETKYTDVAGTMALRKAVAAKFKRDNGIDYTPQEIIVSTGGKQVIFNAMLATVEAGDEVII
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCHHHHHHHHHHHHCCCCEEEE
PTPCWVSYPDIVQLAEGKPVFVPCSQNNGFKLRAEDLEAAITPKTKWLMLNSPSNPTGAA
CCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEECCCCCEEECCCEEEEEEECCCCCCCCC
YSAEDLRPICDVLLRHPDIWVFTDDIYEKLVYDGFAPATIVGVEPKLRERTVTMNGCSKA
CCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCEEEEECCCCHHHCEEEECCCCHH
YAMTGWRIGFCGAPVQLIKAMDKLQSQSTSNTSSVSQVAALAALEGPEDAIDVMRAAYRE
HHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRDLVVAMLNEAPGITCSKPEGAFYVFPSIAGCLGKTSAGGTKIVDDEAFVTALLEEQGV
HHHEEEEEECCCCCCEECCCCCCEEECCHHHHHHCCCCCCCCEEECCHHHHHHHHHHCCC
AAVHGSAFIYPGYFRVSYATSTEALRDACTRIQTFCQGLR
EEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLIAARLNRISPSQTIAISTKARQLKAEGRDIISLSAGEPDFDTPDHIKRAAIAAIEAG
CCCHHHHHHCCCCCCEEEEEHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHEECC
ETKYTDVAGTMALRKAVAAKFKRDNGIDYTPQEIIVSTGGKQVIFNAMLATVEAGDEVII
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCHHHHHHHHHHHHCCCCEEEE
PTPCWVSYPDIVQLAEGKPVFVPCSQNNGFKLRAEDLEAAITPKTKWLMLNSPSNPTGAA
CCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEECCCCCEEECCCEEEEEEECCCCCCCCC
YSAEDLRPICDVLLRHPDIWVFTDDIYEKLVYDGFAPATIVGVEPKLRERTVTMNGCSKA
CCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCEEEEECCCCHHHCEEEECCCCHH
YAMTGWRIGFCGAPVQLIKAMDKLQSQSTSNTSSVSQVAALAALEGPEDAIDVMRAAYRE
HHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRDLVVAMLNEAPGITCSKPEGAFYVFPSIAGCLGKTSAGGTKIVDDEAFVTALLEEQGV
HHHEEEEEECCCCCCEECCCCCCEEECCHHHHHHCCCCCCCCEEECCHHHHHHHHHHCCC
AAVHGSAFIYPGYFRVSYATSTEALRDACTRIQTFCQGLR
EEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]