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The map label for this gene is waaA [H]

Identifier: 148259664

GI number: 148259664

Start: 733865

End: 735103

Strand: Reverse

Name: waaA [H]

Synonym: Acry_0651

Alternate gene names: 148259664

Gene position: 735103-733865 (Counterclockwise)

Preceding gene: 148259665

Following gene: 148259663

Centisome position: 21.69

GC content: 76.27

Gene sequence:

>1239_bases
ATGCCGGCAGGCCTGACCGCCTATCGCCTCGCCACCGCCGGCATCGCCCCGCTGCTGCCGTTCTGGCTGGCGCGGCGGGC
GCGGCGCGGCAAGGAAATCGCCGCCCGCCTGCCGGAGCGCTACGGCATCGCCGGGCTGGCGCGGCCGCCGGGCCGGCTCG
TCTGGGTCCATGCCGCCAGCATGGGCGAGACGATGTCCGCCCTCGGCATGATCGACGCCCTGGCCGACCGCGCAACCGTG
CTGCTGACCACCGGCACCCGCACCGCCGCCGCCCTTGCCGAATCGCGGGCGCGGGCGCTGCACCAGTTCGTCCCGCTCGA
CGTCGCCGCCCATGCCACGCGCTTCCTCGACCATTGGCGGCCGGACGCGGCGGTGTTCCTCGAATCCGAGATCTGGCCGA
ACCTGCTCGCCGGGCTCGACGCGCGGCGCATCCCCCGCTTCCTGTTCAACGCCCGCCTCTCCGCCCGCAGCGCCGCGCGC
TGGCGCCGCGCCCCCACCCTCGCCCGCGCCCTGTTCGGCGGGTTCCGGCTGATCGCCGCGCAATCGGCGCCGGATGCCGC
TTCGCTGCGCGGCCTCGGCCTCACCCGCGTCGAGACCTGGGGCAACCTGAAATTCGCCGCCCCCGACCTGCCGGACGATC
CCGCCGCCCGCGCCGCACTCGCCGCCGCCGCAGCCGGCCCGTTCATCCTCGCCGCCAGCACCCATCCGGGCGAGGATGCG
CCGGTGATCGCCGCGCATCGCATTCTGCGCGAAACCCGGCCCGGCCTCGTCACCATCATCGCGCCGCGCCATCCCGAACG
CGCCGACGCCATCGCCGGTCTCGCCGGCGATCTGCCCGTTTCCCGGCGCTCGCGCGGCGAGGCGCCCGCCGCCGGCGGGC
TCTACATCGCCGACACGCTGGGCGAACTCGGCCTGTTCTACCGTCTCGCCGCCGTTTCCTTCATCGGCGGCTCGCTGGTC
CCCATCGGCGGCCACAACATGATCGAGGCGGCGCAGCTCGGCTGCCCCGTGCTCACCGGCCCGCATCTGGCGAATTTCGC
CGAGGCCGCGGCAACGCTGCGCACGGCCGGCGCCCTTGCCGATCTCGCCGGGCCGGACGACCTCGCCCCCGCCGTCGCCG
CCCTGCTCGACGATCCCGCCCGCCGCGCCGCGATGGCCGCATCCGGCCGCGCCGCCTGCGCCGGGCTCGCCGGCCTGCCC
GCCCGGCTGGCCCGCACCGTTCTCGACGAGGCTCCCTGA

Upstream 100 bases:

>100_bases
TCGCCTCGGCGCCGATCGCCGTCTCCCGGGACGACTGGGCAACCGCGCTGCCGCAGATCGAGGCCGAGATGAGCCGCACG
CTGGACGAGGCGCTCGCGCG

Downstream 100 bases:

>100_bases
TGCGCGCCCCCGCCTTCTGGACCACCGACGCCTTCCCGGCGCCGCTCCTCGCCCCGCTCGGCGCGATCACGCGCGCGCTG
ACCGCCCGGCGCGTCGCCCG

Product: 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MPAGLTAYRLATAGIAPLLPFWLARRARRGKEIAARLPERYGIAGLARPPGRLVWVHAASMGETMSALGMIDALADRATV
LLTTGTRTAAALAESRARALHQFVPLDVAAHATRFLDHWRPDAAVFLESEIWPNLLAGLDARRIPRFLFNARLSARSAAR
WRRAPTLARALFGGFRLIAAQSAPDAASLRGLGLTRVETWGNLKFAAPDLPDDPAARAALAAAAAGPFILAASTHPGEDA
PVIAAHRILRETRPGLVTIIAPRHPERADAIAGLAGDLPVSRRSRGEAPAAGGLYIADTLGELGLFYRLAAVSFIGGSLV
PIGGHNMIEAAQLGCPVLTGPHLANFAEAAATLRTAGALADLAGPDDLAPAVAALLDDPARRAAMAASGRAACAGLAGLP
ARLARTVLDEAP

Sequences:

>Translated_412_residues
MPAGLTAYRLATAGIAPLLPFWLARRARRGKEIAARLPERYGIAGLARPPGRLVWVHAASMGETMSALGMIDALADRATV
LLTTGTRTAAALAESRARALHQFVPLDVAAHATRFLDHWRPDAAVFLESEIWPNLLAGLDARRIPRFLFNARLSARSAAR
WRRAPTLARALFGGFRLIAAQSAPDAASLRGLGLTRVETWGNLKFAAPDLPDDPAARAALAAAAAGPFILAASTHPGEDA
PVIAAHRILRETRPGLVTIIAPRHPERADAIAGLAGDLPVSRRSRGEAPAAGGLYIADTLGELGLFYRLAAVSFIGGSLV
PIGGHNMIEAAQLGCPVLTGPHLANFAEAAATLRTAGALADLAGPDDLAPAVAALLDDPARRAAMAASGRAACAGLAGLP
ARLARTVLDEAP
>Mature_411_residues
PAGLTAYRLATAGIAPLLPFWLARRARRGKEIAARLPERYGIAGLARPPGRLVWVHAASMGETMSALGMIDALADRATVL
LTTGTRTAAALAESRARALHQFVPLDVAAHATRFLDHWRPDAAVFLESEIWPNLLAGLDARRIPRFLFNARLSARSAARW
RRAPTLARALFGGFRLIAAQSAPDAASLRGLGLTRVETWGNLKFAAPDLPDDPAARAALAAAAAGPFILAASTHPGEDAP
VIAAHRILRETRPGLVTIIAPRHPERADAIAGLAGDLPVSRRSRGEAPAAGGLYIADTLGELGLFYRLAAVSFIGGSLVP
IGGHNMIEAAQLGCPVLTGPHLANFAEAAATLRTAGALADLAGPDDLAPAVAALLDDPARRAAMAASGRAACAGLAGLPA
RLARTVLDEAP

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=381, Percent_Identity=38.3202099737533, Blast_Score=209, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 42859; Mature: 42728

Theoretical pI: Translated: 11.17; Mature: 11.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGLTAYRLATAGIAPLLPFWLARRARRGKEIAARLPERYGIAGLARPPGRLVWVHAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCCCCCEEEEEECC
MGETMSALGMIDALADRATVLLTTGTRTAAALAESRARALHQFVPLDVAAHATRFLDHWR
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
PDAAVFLESEIWPNLLAGLDARRIPRFLFNARLSARSAARWRRAPTLARALFGGFRLIAA
CCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
QSAPDAASLRGLGLTRVETWGNLKFAAPDLPDDPAARAALAAAAAGPFILAASTHPGEDA
CCCCCHHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCC
PVIAAHRILRETRPGLVTIIAPRHPERADAIAGLAGDLPVSRRSRGEAPAAGGLYIADTL
CHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHH
GELGLFYRLAAVSFIGGSLVPIGGHNMIEAAQLGCPVLTGPHLANFAEAAATLRTAGALA
HHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DLAGPDDLAPAVAALLDDPARRAAMAASGRAACAGLAGLPARLARTVLDEAP
HCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
PAGLTAYRLATAGIAPLLPFWLARRARRGKEIAARLPERYGIAGLARPPGRLVWVHAAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCCCCCEEEEEECC
MGETMSALGMIDALADRATVLLTTGTRTAAALAESRARALHQFVPLDVAAHATRFLDHWR
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
PDAAVFLESEIWPNLLAGLDARRIPRFLFNARLSARSAARWRRAPTLARALFGGFRLIAA
CCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
QSAPDAASLRGLGLTRVETWGNLKFAAPDLPDDPAARAALAAAAAGPFILAASTHPGEDA
CCCCCHHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCC
PVIAAHRILRETRPGLVTIIAPRHPERADAIAGLAGDLPVSRRSRGEAPAAGGLYIADTL
CHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHH
GELGLFYRLAAVSFIGGSLVPIGGHNMIEAAQLGCPVLTGPHLANFAEAAATLRTAGALA
HHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DLAGPDDLAPAVAALLDDPARRAAMAASGRAACAGLAGLPARLARTVLDEAP
HCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA