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The map label for this gene is pheA [H]

Identifier: 148259655

GI number: 148259655

Start: 725177

End: 726040

Strand: Reverse

Name: pheA [H]

Synonym: Acry_0642

Alternate gene names: 148259655

Gene position: 726040-725177 (Counterclockwise)

Preceding gene: 148259656

Following gene: 148259654

Centisome position: 21.42

GC content: 71.06

Gene sequence:

>864_bases
ATGACAACCCGAATCGCCTTCCAGGGCGCGCCCGGCGCCTATTCCGACCTCGCCTGCCGCACCGCCTATCCCGGCATGGC
CACCCTGCCCTGCCAGACCTTCGAGGCGGCGATCGAGGCGGTGAAGACCGGCGAGGCCGAATTCGCCATGCTGCCGACCG
AGAACTCGCTCGCCGGCCGGGTGCCGGACATGCACGCCCTGCTGCCCGAGTCCGGGCTTTCGATCATCGCGGAGCATTTC
CAGCGGGTGGAGCACTGCCTGCTGGCGCCGCGGGGCGCCAGCCTCGCCGGCATCCGTCAGGTGCATTCCCATGCCGTCGC
CCTCGGCCAGGTGCGCGCGCTGATCCGCGAGCTCGGGGCCCAGGCCGTGGTCGAGGCGGATACCGCCGGCTCGGCCGAAC
TCGTCGCCCGCTGGAACGATCCCACCCGCGCCGCGATCGCCTCCTCCCTCGCGGCCGAGATCTACGGGCTCGACATCCTC
CGCCGCAACGTCGAGGACGCGGCGCACAACACCACCCGCTTCTACGTCATGGCCCGCACGCCCCGCCTGCCGCCGCCGGA
CCAGGCGGACCTGATCACCTGTTTCGTCTTCCGCGTGCGCAACGTGCCGGCCGCGCTCTACAAGGCGCTCGGCGGCTTCG
CCACCAACTCGGTGAACATGACGCGGCTGGAGAGCTACATGGTCGGCGGCCAGTTCGCCGCCACCCAGTTCCTGAGCGAG
ATCGACGGCCACCCCGAACAGCGCCACGTGCGCCTCGCCCTCGAGGAGCTCGATTTCTTCTCGCGCGAAATCCGCATCCT
CGGCGTGTATCCGGCGGCGCCGTTCCGCCTCCAGCAGCGCGCGACCGGGCCCGCCGCGGATTGA

Upstream 100 bases:

>100_bases
TCGAACTCGGGATGCGGATCGGCGCGGCGCGGATTGACCGGGCCCCGTTCGGGGTCGATACCCCGGAAGACCTCGACCGC
GCCCGCAGGAACCTTGCCGC

Downstream 100 bases:

>100_bases
AACCTCTGGTGGAAAAATCGGAAAATATTCGTCAATTTCAGGATTTTTCCGAAAATCGAGCCATATTTCGTTTGTCATGA
CGGAACAGTTCTGCTAACGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTTRIAFQGAPGAYSDLACRTAYPGMATLPCQTFEAAIEAVKTGEAEFAMLPTENSLAGRVPDMHALLPESGLSIIAEHF
QRVEHCLLAPRGASLAGIRQVHSHAVALGQVRALIRELGAQAVVEADTAGSAELVARWNDPTRAAIASSLAAEIYGLDIL
RRNVEDAAHNTTRFYVMARTPRLPPPDQADLITCFVFRVRNVPAALYKALGGFATNSVNMTRLESYMVGGQFAATQFLSE
IDGHPEQRHVRLALEELDFFSREIRILGVYPAAPFRLQQRATGPAAD

Sequences:

>Translated_287_residues
MTTRIAFQGAPGAYSDLACRTAYPGMATLPCQTFEAAIEAVKTGEAEFAMLPTENSLAGRVPDMHALLPESGLSIIAEHF
QRVEHCLLAPRGASLAGIRQVHSHAVALGQVRALIRELGAQAVVEADTAGSAELVARWNDPTRAAIASSLAAEIYGLDIL
RRNVEDAAHNTTRFYVMARTPRLPPPDQADLITCFVFRVRNVPAALYKALGGFATNSVNMTRLESYMVGGQFAATQFLSE
IDGHPEQRHVRLALEELDFFSREIRILGVYPAAPFRLQQRATGPAAD
>Mature_286_residues
TTRIAFQGAPGAYSDLACRTAYPGMATLPCQTFEAAIEAVKTGEAEFAMLPTENSLAGRVPDMHALLPESGLSIIAEHFQ
RVEHCLLAPRGASLAGIRQVHSHAVALGQVRALIRELGAQAVVEADTAGSAELVARWNDPTRAAIASSLAAEIYGLDILR
RNVEDAAHNTTRFYVMARTPRLPPPDQADLITCFVFRVRNVPAALYKALGGFATNSVNMTRLESYMVGGQFAATQFLSEI
DGHPEQRHVRLALEELDFFSREIRILGVYPAAPFRLQQRATGPAAD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=276, Percent_Identity=30.7971014492754, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31099; Mature: 30968

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRIAFQGAPGAYSDLACRTAYPGMATLPCQTFEAAIEAVKTGEAEFAMLPTENSLAGR
CCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
VPDMHALLPESGLSIIAEHFQRVEHCLLAPRGASLAGIRQVHSHAVALGQVRALIRELGA
CCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QAVVEADTAGSAELVARWNDPTRAAIASSLAAEIYGLDILRRNVEDAAHNTTRFYVMART
HHEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
PRLPPPDQADLITCFVFRVRNVPAALYKALGGFATNSVNMTRLESYMVGGQFAATQFLSE
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
IDGHPEQRHVRLALEELDFFSREIRILGVYPAAPFRLQQRATGPAAD
HCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TTRIAFQGAPGAYSDLACRTAYPGMATLPCQTFEAAIEAVKTGEAEFAMLPTENSLAGR
CCEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
VPDMHALLPESGLSIIAEHFQRVEHCLLAPRGASLAGIRQVHSHAVALGQVRALIRELGA
CCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QAVVEADTAGSAELVARWNDPTRAAIASSLAAEIYGLDILRRNVEDAAHNTTRFYVMART
HHEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEC
PRLPPPDQADLITCFVFRVRNVPAALYKALGGFATNSVNMTRLESYMVGGQFAATQFLSE
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
IDGHPEQRHVRLALEELDFFSREIRILGVYPAAPFRLQQRATGPAAD
HCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]