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The map label for this gene is kdsB [H]

Identifier: 148259656

GI number: 148259656

Start: 726037

End: 726780

Strand: Reverse

Name: kdsB [H]

Synonym: Acry_0643

Alternate gene names: 148259656

Gene position: 726780-726037 (Counterclockwise)

Preceding gene: 148259660

Following gene: 148259655

Centisome position: 21.44

GC content: 71.24

Gene sequence:

>744_bases
ATGGAGGCAGACATTCCGGCTCCCATCGTTCTGATCCCGGCACGGCTCGGCTCGACCCGCCTGCCCGGCAAGCCCCTCGC
CGATATCGGCGGAATTCCGATGATTGTCCATGTCCTCCGCCGCGCCGGGGAAGCGGCGATCGGCCCGGTCGCGGTGGCCT
GCGCCGAATCCGCGATCGCCGACGCCGTCCGCGCGGCCGGCGGCACCGCGGTGCTGACCGACCCCGACCTGCCGAGCGGA
TCGGACCGGATCCACGCCGCCCTCGCCACGATCGACCCGGCTTGCGTTCATGACATCGTGGTGAATCTCCAGGGCGATCT
TCCGGGCTTCCCTCCCGAATCGCTGCGCACCCTGATCGCCGTGCTCGACGATCCGGGCTTCGACATCGCCACCCTCGTCG
CCCCCGTCACCACGGCGGAAGAGGCCGCCTCCCCCTCGGTGGTCAAGGCGGCCTGCGGCTTCGGCGAGGGGATCGCCGCC
CCCGCGCTCTATTTCTCGCGCAACCCGATCCCCTCGGGGCCGGGGCCGCTCTGGCACCATGTCGGCGTCTACGCCTATCG
CCGCGCCGCACTCGACCGTTTCGTCGCGGCACCGCCCTCGCCGCTCGAACTGCGCGAAAAGCTCGAACAGCTCCGCGCCC
TCGAACTCGGGATGCGGATCGGCGCGGCGCGGATTGACCGGGCCCCGTTCGGGGTCGATACCCCGGAAGACCTCGACCGC
GCCCGCAGGAACCTTGCCGCATGA

Upstream 100 bases:

>100_bases
TCACTCATAAGCGCGGTCCCTCCAAAGCTTTACGGACGGATGTATAGCGATTTAGGAAAGTGCGACAAGCGATAACAGTC
GCGTTCGCCATGCGACCTTC

Downstream 100 bases:

>100_bases
CAACCCGAATCGCCTTCCAGGGCGCGCCCGGCGCCTATTCCGACCTCGCCTGCCGCACCGCCTATCCCGGCATGGCCACC
CTGCCCTGCCAGACCTTCGA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEADIPAPIVLIPARLGSTRLPGKPLADIGGIPMIVHVLRRAGEAAIGPVAVACAESAIADAVRAAGGTAVLTDPDLPSG
SDRIHAALATIDPACVHDIVVNLQGDLPGFPPESLRTLIAVLDDPGFDIATLVAPVTTAEEAASPSVVKAACGFGEGIAA
PALYFSRNPIPSGPGPLWHHVGVYAYRRAALDRFVAAPPSPLELREKLEQLRALELGMRIGAARIDRAPFGVDTPEDLDR
ARRNLAA

Sequences:

>Translated_247_residues
MEADIPAPIVLIPARLGSTRLPGKPLADIGGIPMIVHVLRRAGEAAIGPVAVACAESAIADAVRAAGGTAVLTDPDLPSG
SDRIHAALATIDPACVHDIVVNLQGDLPGFPPESLRTLIAVLDDPGFDIATLVAPVTTAEEAASPSVVKAACGFGEGIAA
PALYFSRNPIPSGPGPLWHHVGVYAYRRAALDRFVAAPPSPLELREKLEQLRALELGMRIGAARIDRAPFGVDTPEDLDR
ARRNLAA
>Mature_247_residues
MEADIPAPIVLIPARLGSTRLPGKPLADIGGIPMIVHVLRRAGEAAIGPVAVACAESAIADAVRAAGGTAVLTDPDLPSG
SDRIHAALATIDPACVHDIVVNLQGDLPGFPPESLRTLIAVLDDPGFDIATLVAPVTTAEEAASPSVVKAACGFGEGIAA
PALYFSRNPIPSGPGPLWHHVGVYAYRRAALDRFVAAPPSPLELREKLEQLRALELGMRIGAARIDRAPFGVDTPEDLDR
ARRNLAA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=249, Percent_Identity=42.9718875502008, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 25619; Mature: 25619

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEADIPAPIVLIPARLGSTRLPGKPLADIGGIPMIVHVLRRAGEAAIGPVAVACAESAIA
CCCCCCCCEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAVRAAGGTAVLTDPDLPSGSDRIHAALATIDPACVHDIVVNLQGDLPGFPPESLRTLIA
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VLDDPGFDIATLVAPVTTAEEAASPSVVKAACGFGEGIAAPALYFSRNPIPSGPGPLWHH
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHH
VGVYAYRRAALDRFVAAPPSPLELREKLEQLRALELGMRIGAARIDRAPFGVDTPEDLDR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ARRNLAA
HHHHCCC
>Mature Secondary Structure
MEADIPAPIVLIPARLGSTRLPGKPLADIGGIPMIVHVLRRAGEAAIGPVAVACAESAIA
CCCCCCCCEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAVRAAGGTAVLTDPDLPSGSDRIHAALATIDPACVHDIVVNLQGDLPGFPPESLRTLIA
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VLDDPGFDIATLVAPVTTAEEAASPSVVKAACGFGEGIAAPALYFSRNPIPSGPGPLWHH
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHH
VGVYAYRRAALDRFVAAPPSPLELREKLEQLRALELGMRIGAARIDRAPFGVDTPEDLDR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ARRNLAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA