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The map label for this gene is aatA [H]

Identifier: 148259122

GI number: 148259122

Start: 110707

End: 111912

Strand: Reverse

Name: aatA [H]

Synonym: Acry_0102

Alternate gene names: 148259122

Gene position: 111912-110707 (Counterclockwise)

Preceding gene: 148259123

Following gene: 148259118

Centisome position: 3.3

GC content: 59.62

Gene sequence:

>1206_bases
ATGATCCAATTTTCCGCCCGCGTCGGCCGAACAAGGCCGGCGGCTACTTTCGCTATGGCTGCCCGGGCTCGCGCTCTTCG
TGCCGCTGGCCATGATGTGATTTCGCTATCGATCGGCGAGCCCGACCTTCCAACCCCACCGCATGTCGTTGATGCCGCAC
ACCGTGCCGCACTCGGCGGGCAGACACGCTACCCCCCTATCGCTGGAACCGATGCGCTGCGCTGCGCCGCAGCACGGAAA
TTCGAACGCGATCAGGGTTTGCCGGCAACACCAGCTGACGTTCTTGTCACAAATGGCGGCAAGCAGGCGATATTTGACGC
CGTGATGTCGGTCATCGATCCTGGCGATGAAGTGCTTATTCCCGCGCCTTGCTGGGCAGGCTACATCCAGGTGGTTGAAT
TCGCCGGTGGTATCCCGGTGTTCATCGATTGCCCCGCCGAAGCAGGATTCCGCGTGGATGCTGCCACCCTCGCGGCAGCT
ATCGGGCCAAGGACGAAGCTCCTTGTTCTCAACTATCCAAACAATCCGTCCGGCGCGATTGCCGATGCGGCAATGCTTAT
CGGCATCGCCGATGTGCTTCGTCGGCATCCTCATGTACTGACAATTTCGGATGATATTTACGAGCACCTCATTTTCGAAG
GCGCGTACCTGACATTGGCGGCCGCTGCTCCAGATCTCGCTGGGCGCGTGCTGACTATGTCCGGCGTATCGAAATCCTAT
GCGATGACCGGCTGGCGCCTTGGCTTCTGTACCGGTCCGCGTGACTGGCTAGCGGCAATGACGCTGGTTCAGGGGACTGC
CACTGCGGGTGTTTCGACCATTAGCCAGGCGGCTGCTGTTGCGGCGCTAGACGGCCCGCAGGATCTTCTCGAGGAACGAC
GTACGATTTATCGTCGACGCCGCGATCTTGTTCTAGGTGCGCTGGCCGGTGCGCCTGGCCTTACCTGTTCCCGCCCAGAG
GGAGCTTTCTACGCCTTCCCGTCGATCACCAGTCTATTGGGTTGCCGGACCCCGAGCGGCCGAATACTTGGCAATGATGA
GGATGTGGCGAATGCCTTACTAGATGAGGCTTTGGTCGCTACGGTTCCGGGCTCCGCGTTTGCAATGCCAGGTCATATCC
GGCTTTCGACGGCTGCATCCGATGCCCTTCTGGAAGAGGCCTGCGAGCGCATTCTACGATTTTGCATAACGACATGTAAC
CATTAA

Upstream 100 bases:

>100_bases
GGTCGTAATCTCGGTGCCGCGTTGCGCTATGCGTGGCAGGATTATTGTCGTAACGGCTGCCGGGCTTGATCAATCGCCGC
AACTGTGGTGCTGACGCGGG

Downstream 100 bases:

>100_bases
TTTAGGGTTTGTGGGGATTCATCGTGAGTTGATGACGGCTGCGGCGAGGTGGATCATTGGCTGGAAGCTCTGGTCTGTTT
TGCAGGCGCGCAGGGCGATG

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MIQFSARVGRTRPAATFAMAARARALRAAGHDVISLSIGEPDLPTPPHVVDAAHRAALGGQTRYPPIAGTDALRCAAARK
FERDQGLPATPADVLVTNGGKQAIFDAVMSVIDPGDEVLIPAPCWAGYIQVVEFAGGIPVFIDCPAEAGFRVDAATLAAA
IGPRTKLLVLNYPNNPSGAIADAAMLIGIADVLRRHPHVLTISDDIYEHLIFEGAYLTLAAAAPDLAGRVLTMSGVSKSY
AMTGWRLGFCTGPRDWLAAMTLVQGTATAGVSTISQAAAVAALDGPQDLLEERRTIYRRRRDLVLGALAGAPGLTCSRPE
GAFYAFPSITSLLGCRTPSGRILGNDEDVANALLDEALVATVPGSAFAMPGHIRLSTAASDALLEEACERILRFCITTCN
H

Sequences:

>Translated_401_residues
MIQFSARVGRTRPAATFAMAARARALRAAGHDVISLSIGEPDLPTPPHVVDAAHRAALGGQTRYPPIAGTDALRCAAARK
FERDQGLPATPADVLVTNGGKQAIFDAVMSVIDPGDEVLIPAPCWAGYIQVVEFAGGIPVFIDCPAEAGFRVDAATLAAA
IGPRTKLLVLNYPNNPSGAIADAAMLIGIADVLRRHPHVLTISDDIYEHLIFEGAYLTLAAAAPDLAGRVLTMSGVSKSY
AMTGWRLGFCTGPRDWLAAMTLVQGTATAGVSTISQAAAVAALDGPQDLLEERRTIYRRRRDLVLGALAGAPGLTCSRPE
GAFYAFPSITSLLGCRTPSGRILGNDEDVANALLDEALVATVPGSAFAMPGHIRLSTAASDALLEEACERILRFCITTCN
H
>Mature_401_residues
MIQFSARVGRTRPAATFAMAARARALRAAGHDVISLSIGEPDLPTPPHVVDAAHRAALGGQTRYPPIAGTDALRCAAARK
FERDQGLPATPADVLVTNGGKQAIFDAVMSVIDPGDEVLIPAPCWAGYIQVVEFAGGIPVFIDCPAEAGFRVDAATLAAA
IGPRTKLLVLNYPNNPSGAIADAAMLIGIADVLRRHPHVLTISDDIYEHLIFEGAYLTLAAAAPDLAGRVLTMSGVSKSY
AMTGWRLGFCTGPRDWLAAMTLVQGTATAGVSTISQAAAVAALDGPQDLLEERRTIYRRRRDLVLGALAGAPGLTCSRPE
GAFYAFPSITSLLGCRTPSGRILGNDEDVANALLDEALVATVPGSAFAMPGHIRLSTAASDALLEEACERILRFCITTCN
H

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=325, Percent_Identity=30.1538461538462, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI169881279, Length=325, Percent_Identity=30.1538461538462, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=29.2105263157895, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=25.0639386189258, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=25.0639386189258, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI169881281, Length=322, Percent_Identity=24.8447204968944, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=30.9333333333333, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=27.2959183673469, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=27.6923076923077, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790797, Length=303, Percent_Identity=28.7128712871287, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787710, Length=242, Percent_Identity=27.6859504132231, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=433, Percent_Identity=25.4041570438799, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=400, Percent_Identity=26, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=27.34375, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=405, Percent_Identity=24.6913580246914, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=25.3846153846154, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573069, Length=258, Percent_Identity=27.1317829457364, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646114, Length=258, Percent_Identity=27.1317829457364, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573067, Length=258, Percent_Identity=27.1317829457364, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573065, Length=258, Percent_Identity=27.1317829457364, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=26.8421052631579, Blast_Score=118, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42032; Mature: 42032

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFSARVGRTRPAATFAMAARARALRAAGHDVISLSIGEPDLPTPPHVVDAAHRAALGG
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCC
QTRYPPIAGTDALRCAAARKFERDQGLPATPADVLVTNGGKQAIFDAVMSVIDPGDEVLI
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEE
PAPCWAGYIQVVEFAGGIPVFIDCPAEAGFRVDAATLAAAIGPRTKLLVLNYPNNPSGAI
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHHHHHCCCCEEEEEEECCCCCCCHH
ADAAMLIGIADVLRRHPHVLTISDDIYEHLIFEGAYLTLAAAAPDLAGRVLTMSGVSKSY
HHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCHHEEEEECCCCHHCEEEEECCCCCHH
AMTGWRLGFCTGPRDWLAAMTLVQGTATAGVSTISQAAAVAALDGPQDLLEERRTIYRRR
EECCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RDLVLGALAGAPGLTCSRPEGAFYAFPSITSLLGCRTPSGRILGNDEDVANALLDEALVA
HHHHEEHHCCCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHH
TVPGSAFAMPGHIRLSTAASDALLEEACERILRFCITTCNH
CCCCCCEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQFSARVGRTRPAATFAMAARARALRAAGHDVISLSIGEPDLPTPPHVVDAAHRAALGG
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCC
QTRYPPIAGTDALRCAAARKFERDQGLPATPADVLVTNGGKQAIFDAVMSVIDPGDEVLI
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEE
PAPCWAGYIQVVEFAGGIPVFIDCPAEAGFRVDAATLAAAIGPRTKLLVLNYPNNPSGAI
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHHHHHCCCCEEEEEEECCCCCCCHH
ADAAMLIGIADVLRRHPHVLTISDDIYEHLIFEGAYLTLAAAAPDLAGRVLTMSGVSKSY
HHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCHHEEEEECCCCHHCEEEEECCCCCHH
AMTGWRLGFCTGPRDWLAAMTLVQGTATAGVSTISQAAAVAALDGPQDLLEERRTIYRRR
EECCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RDLVLGALAGAPGLTCSRPEGAFYAFPSITSLLGCRTPSGRILGNDEDVANALLDEALVA
HHHHEEHHCCCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHH
TVPGSAFAMPGHIRLSTAASDALLEEACERILRFCITTCNH
CCCCCCEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]