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The map label for this gene is htpG [H]

Identifier: 148242470

GI number: 148242470

Start: 1216612

End: 1218516

Strand: Direct

Name: htpG [H]

Synonym: SynRCC307_1371

Alternate gene names: 148242470

Gene position: 1216612-1218516 (Clockwise)

Preceding gene: 148242469

Following gene: 148242472

Centisome position: 54.68

GC content: 59.21

Gene sequence:

>1905_bases
ATGTCGGTGCTTGAGCAAGGCCAGATCCAGATCCATACCGAAAACATCTTCCCGATCATCAAGAAGGCCGTTTACAGCGG
CCACGAGGTGTTTTTGCGTGAATTGGTCAGCAACGGCACCGATGCGATCAGCAAGCGCCGAATGGCGGCCATGGCTGGTG
ATTGCAGCGAAGGCAGCGACGGACTGATCAGCATCAAGATCGATCGCGAAGCCAAAACCCTCACCATCAGCGACAACGGC
ATCGGCATGAACGCCGATGAGGTGAAGCGCTACATCAACCAGGTGGCCTTCTCCAGCGCCGAGGAATTCCTGGAGAAGTA
CAAGAGCGAAGACGACGCCATCATTGGCCACTTTGGCCTGGGCTTTTATTCGAGCTTCATGGTGGCCAGCCAGGTTGAGC
TGGTGAGCTTGAGCGCTCGCCCCAACGCTGAAGCGGTCCGCTGGAGCTGCGATGGCTCACCGAATTTCAGCCTCGAAGCC
GCTGAGCGCAGCGAACCCGGCACCGATGTGATCCTGCACCTGCAGGAGGAGGAGCTCGAGTACATCGAGCCCGCCCGGAT
TCGCACCTTGATCAACACCTACTGCGACTTCATGCCGGTGGAGGTGCAGCTGGAAGGGGAGACGGTCAACAAGCGCGAAG
CCCCCTGGCGCAAGAGTCCCCGGGAGCTCAGCGATGAGGACTACATCGAGCTGTACCGCTACCTCTATCCATTCCAAGGC
GATCCCCTGCTGTGGGTTCACCTCAACACCGATTACCCCTACAACCTGCAAGGCATCCTCTATTTCCCAAAATCCACCGG
CCGCGCTGATTGGGAAAAGGGCGAAATCAAGCTGTACTGCAATCAGGTCTTTGTCAGCGACTCCATCAAGGAGGTGGTGC
CGAAGTATCTGCTGCCCTTGCGCGGGGTGATCGATTCACCCGATATCCCACTCAACGTGAGCCGCTCGGCGCTGCAGACC
GATCGCCGGGTGCGCTCCATCGGCGGCTTTGTGGCCAAGAAGGTGGGCGACCGGTTGAAGCAGCTGCATCGTGATGAGCC
CAAGCGCTATGCCGAAATTTGGGAGTCGTTGGCTCCCTTCATCAAGATCGGCGCCATGGAGGATGAGAAGTTTGCTGATC
AAGTCGCCGAGCTGGTGTTGTTTGGCACCACCGCAGCGGCAGGCGAAGGCGAAACCCCCGATCCGGTCGCAGCTGAAGAC
GGCAAGCGATTTACCACCCTGGGGGGTTACCGCTCACGGCTCAGCGCCGATAACGACAAGCGCATCCTTTATTGCACCGA
TGAGGCCGGGCAGGCCGGGGCCTTGGCGCTCTGGCAAGGGCAAGGCGCTGAAGTGCTGCTGGCTGACACCTTCATCGACA
CACAGTTCATTCCTTGGCTGGAATACCGCCACGAGGAGTTGAAGTTCCAGCGGGTGGATGCCGAGCTGGATGATTCTCTG
CAAGACAAAGACAGCGGCGTTACCGATGCTGAAGGCAAAGACAGCAGTGAAAGCCTGCGGGATCTGTTTAAGGCCTCACT
GGATAACGACAAAGTCACCATCCAGGTGCAGGCTCTCAAGGGTGACAACGCCCCGGCTGCGTTGATCCTGCTGCCAGAGC
AAATGCGCCGCATGAACGACATGGGCGCCCTGATGGAGCAACGCCTCCCGGGCCTGCCTGATCACCACGTGCTGCTGATC
AACCGCCGGCACCGGTTGGTCGAAGGCATGCAAAAGCTGGCCGCTGGATCTGTGATTGCCGGCGGGGGCGCGAGCTCGCC
GAGCCAACAACTCGCCGAGCAACTCAGCCGCCATGTCTATGAAATGGCCAAGCTTTCGGTTGGAGGATTGGAGCCCAATG
AATTGGCCGGCTTCCAACAGCGAAGCTGCGACCTGATGGGTGAGCTGATGAACCGGGGGCTTTAA

Upstream 100 bases:

>100_bases
AACCAGCAACTGAGTCACTGGTTCGGGCTTCACACCACTGCAGCCATTGAGCGGGTCGCCCTCCTGTTCCTAGGGTCGTG
GACCCCAATTCAGACGGCGC

Downstream 100 bases:

>100_bases
GCCCCTGGGCTCAGACCGAAGCGGCGCGGCGCTTGAGATACCACTGCAGCATCGAAGGGTGCTGCAGTTGGAAACCCAAG
TCTTTCAACGACTCATTCGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSVLEQGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGTDAISKRRMAAMAGDCSEGSDGLISIKIDREAKTLTISDNG
IGMNADEVKRYINQVAFSSAEEFLEKYKSEDDAIIGHFGLGFYSSFMVASQVELVSLSARPNAEAVRWSCDGSPNFSLEA
AERSEPGTDVILHLQEEELEYIEPARIRTLINTYCDFMPVEVQLEGETVNKREAPWRKSPRELSDEDYIELYRYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPKSTGRADWEKGEIKLYCNQVFVSDSIKEVVPKYLLPLRGVIDSPDIPLNVSRSALQT
DRRVRSIGGFVAKKVGDRLKQLHRDEPKRYAEIWESLAPFIKIGAMEDEKFADQVAELVLFGTTAAAGEGETPDPVAAED
GKRFTTLGGYRSRLSADNDKRILYCTDEAGQAGALALWQGQGAEVLLADTFIDTQFIPWLEYRHEELKFQRVDAELDDSL
QDKDSGVTDAEGKDSSESLRDLFKASLDNDKVTIQVQALKGDNAPAALILLPEQMRRMNDMGALMEQRLPGLPDHHVLLI
NRRHRLVEGMQKLAAGSVIAGGGASSPSQQLAEQLSRHVYEMAKLSVGGLEPNELAGFQQRSCDLMGELMNRGL

Sequences:

>Translated_634_residues
MSVLEQGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGTDAISKRRMAAMAGDCSEGSDGLISIKIDREAKTLTISDNG
IGMNADEVKRYINQVAFSSAEEFLEKYKSEDDAIIGHFGLGFYSSFMVASQVELVSLSARPNAEAVRWSCDGSPNFSLEA
AERSEPGTDVILHLQEEELEYIEPARIRTLINTYCDFMPVEVQLEGETVNKREAPWRKSPRELSDEDYIELYRYLYPFQG
DPLLWVHLNTDYPYNLQGILYFPKSTGRADWEKGEIKLYCNQVFVSDSIKEVVPKYLLPLRGVIDSPDIPLNVSRSALQT
DRRVRSIGGFVAKKVGDRLKQLHRDEPKRYAEIWESLAPFIKIGAMEDEKFADQVAELVLFGTTAAAGEGETPDPVAAED
GKRFTTLGGYRSRLSADNDKRILYCTDEAGQAGALALWQGQGAEVLLADTFIDTQFIPWLEYRHEELKFQRVDAELDDSL
QDKDSGVTDAEGKDSSESLRDLFKASLDNDKVTIQVQALKGDNAPAALILLPEQMRRMNDMGALMEQRLPGLPDHHVLLI
NRRHRLVEGMQKLAAGSVIAGGGASSPSQQLAEQLSRHVYEMAKLSVGGLEPNELAGFQQRSCDLMGELMNRGL
>Mature_633_residues
SVLEQGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGTDAISKRRMAAMAGDCSEGSDGLISIKIDREAKTLTISDNGI
GMNADEVKRYINQVAFSSAEEFLEKYKSEDDAIIGHFGLGFYSSFMVASQVELVSLSARPNAEAVRWSCDGSPNFSLEAA
ERSEPGTDVILHLQEEELEYIEPARIRTLINTYCDFMPVEVQLEGETVNKREAPWRKSPRELSDEDYIELYRYLYPFQGD
PLLWVHLNTDYPYNLQGILYFPKSTGRADWEKGEIKLYCNQVFVSDSIKEVVPKYLLPLRGVIDSPDIPLNVSRSALQTD
RRVRSIGGFVAKKVGDRLKQLHRDEPKRYAEIWESLAPFIKIGAMEDEKFADQVAELVLFGTTAAAGEGETPDPVAAEDG
KRFTTLGGYRSRLSADNDKRILYCTDEAGQAGALALWQGQGAEVLLADTFIDTQFIPWLEYRHEELKFQRVDAELDDSLQ
DKDSGVTDAEGKDSSESLRDLFKASLDNDKVTIQVQALKGDNAPAALILLPEQMRRMNDMGALMEQRLPGLPDHHVLLIN
RRHRLVEGMQKLAAGSVIAGGGASSPSQQLAEQLSRHVYEMAKLSVGGLEPNELAGFQQRSCDLMGELMNRGL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=635, Percent_Identity=27.244094488189, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI4507677, Length=447, Percent_Identity=27.5167785234899, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI20149594, Length=207, Percent_Identity=32.3671497584541, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI153792590, Length=209, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI154146191, Length=251, Percent_Identity=27.8884462151394, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1786679, Length=591, Percent_Identity=31.3028764805415, Blast_Score=252, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI115535205, Length=643, Percent_Identity=28.3048211508554, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI115535167, Length=401, Percent_Identity=31.6708229426434, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17542208, Length=696, Percent_Identity=25, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17559162, Length=525, Percent_Identity=25.9047619047619, Blast_Score=186, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323840, Length=596, Percent_Identity=26.510067114094, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6325016, Length=217, Percent_Identity=33.1797235023041, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24586016, Length=404, Percent_Identity=32.1782178217822, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI21357739, Length=475, Percent_Identity=28.2105263157895, Blast_Score=185, Evalue=7e-47,
Organism=Drosophila melanogaster, GI17647529, Length=433, Percent_Identity=26.3279445727483, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70771; Mature: 70640

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLEQGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGTDAISKRRMAAMAGDCSEGSD
CCCCCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
GLISIKIDREAKTLTISDNGIGMNADEVKRYINQVAFSSAEEFLEKYKSEDDAIIGHFGL
CEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
GFYSSFMVASQVELVSLSARPNAEAVRWSCDGSPNFSLEAAERSEPGTDVILHLQEEELE
HHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCCEEEECCCCCCCCEEEEEEEHHHHH
YIEPARIRTLINTYCDFMPVEVQLEGETVNKREAPWRKSPRELSDEDYIELYRYLYPFQG
HCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPKSTGRADWEKGEIKLYCNQVFVSDSIKEVVPKYLLPL
CCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQTDRRVRSIGGFVAKKVGDRLKQLHRDEPKRYAEIWESLAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IKIGAMEDEKFADQVAELVLFGTTAAAGEGETPDPVAAEDGKRFTTLGGYRSRLSADNDK
HEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCC
RILYCTDEAGQAGALALWQGQGAEVLLADTFIDTQFIPWLEYRHEELKFQRVDAELDDSL
EEEEEECCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHCCCH
QDKDSGVTDAEGKDSSESLRDLFKASLDNDKVTIQVQALKGDNAPAALILLPEQMRRMND
HHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEECHHHHHHHHH
MGALMEQRLPGLPDHHVLLINRRHRLVEGMQKLAAGSVIAGGGASSPSQQLAEQLSRHVY
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHH
EMAKLSVGGLEPNELAGFQQRSCDLMGELMNRGL
HHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLEQGQIQIHTENIFPIIKKAVYSGHEVFLRELVSNGTDAISKRRMAAMAGDCSEGSD
CCCCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
GLISIKIDREAKTLTISDNGIGMNADEVKRYINQVAFSSAEEFLEKYKSEDDAIIGHFGL
CEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
GFYSSFMVASQVELVSLSARPNAEAVRWSCDGSPNFSLEAAERSEPGTDVILHLQEEELE
HHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCCEEEECCCCCCCCEEEEEEEHHHHH
YIEPARIRTLINTYCDFMPVEVQLEGETVNKREAPWRKSPRELSDEDYIELYRYLYPFQG
HCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
DPLLWVHLNTDYPYNLQGILYFPKSTGRADWEKGEIKLYCNQVFVSDSIKEVVPKYLLPL
CCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHH
RGVIDSPDIPLNVSRSALQTDRRVRSIGGFVAKKVGDRLKQLHRDEPKRYAEIWESLAPF
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IKIGAMEDEKFADQVAELVLFGTTAAAGEGETPDPVAAEDGKRFTTLGGYRSRLSADNDK
HEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCC
RILYCTDEAGQAGALALWQGQGAEVLLADTFIDTQFIPWLEYRHEELKFQRVDAELDDSL
EEEEEECCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHCCCH
QDKDSGVTDAEGKDSSESLRDLFKASLDNDKVTIQVQALKGDNAPAALILLPEQMRRMND
HHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEECHHHHHHHHH
MGALMEQRLPGLPDHHVLLINRRHRLVEGMQKLAAGSVIAGGGASSPSQQLAEQLSRHVY
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHH
EMAKLSVGGLEPNELAGFQQRSCDLMGELMNRGL
HHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]