Click here to switch to the map view.

The map label for this gene is groL [H]

Identifier: 148242356

GI number: 148242356

Start: 1113170

End: 1113592

Strand: Direct

Name: groL [H]

Synonym: SynRCC307_1257

Alternate gene names: 148242356

Gene position: 1113170-1113592 (Clockwise)

Preceding gene: 148242355

Following gene: 148242366

Centisome position: 50.03

GC content: 62.88

Gene sequence:

>423_bases
GTGCCTCGCGCCCCAGGCCGGCGGCAGCAGGAATCGCTGAACGAACTCTGGGTCGGTCGCTGCAACCAGAACCTCAGTGG
TGAAGAGCTGATTGGCGCCAACTTCGTGGCTCAGACCCTTGATGCTCTCCTCAAGCGCATCGCTGAAAACGCCGGTGCCA
ACGGCTCCGTCGTGGCTGAGAACGTGCGCCATAAGCCCTTCAGCGAGGGCTTCAACGCCGCCTCGAACGAGTACGTCGAC
ATGCTGGCTGCCGGCATCATCGACCCCGCCAAGGTGACCCGCTCTGGCCTGCAAAATGCCGCGTCCATCGCTGGCATGGT
GCTGACCACCGAGTGCATCGTGGTTGATCTTCCTGAGAAGAAGGAAGCAGCTCCTGCCGGTGGCGGCATGGGCGGCGGCA
TGGGCGGCCACTTCGACTATTAA

Upstream 100 bases:

>100_bases
GCAGTCATAAAAGGATTCCCTGAGAGGGAAATCGGCAGATGGACCATACCGACGCCATCAAACATCTTCAAGTCGTCTCA
CCCATGAATGGGTCACCGGT

Downstream 100 bases:

>100_bases
TCTCGGAGGAGGGATTCATTCCTCCCCCGCCCACTTCAAACAGTATTTATCGGGGCATTTGCCCCCTTTTTTTGTGCCCA
CGAACCGACAGGCAAAATGT

Product: hypothetical protein

Products: NA

Alternate protein names: GroEL protein; Protein Cpn60 [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MPRAPGRRQQESLNELWVGRCNQNLSGEELIGANFVAQTLDALLKRIAENAGANGSVVAENVRHKPFSEGFNAASNEYVD
MLAAGIIDPAKVTRSGLQNAASIAGMVLTTECIVVDLPEKKEAAPAGGGMGGGMGGHFDY

Sequences:

>Translated_140_residues
MPRAPGRRQQESLNELWVGRCNQNLSGEELIGANFVAQTLDALLKRIAENAGANGSVVAENVRHKPFSEGFNAASNEYVD
MLAAGIIDPAKVTRSGLQNAASIAGMVLTTECIVVDLPEKKEAAPAGGGMGGGMGGHFDY
>Mature_139_residues
PRAPGRRQQESLNELWVGRCNQNLSGEELIGANFVAQTLDALLKRIAENAGANGSVVAENVRHKPFSEGFNAASNEYVDM
LAAGIIDPAKVTRSGLQNAASIAGMVLTTECIVVDLPEKKEAAPAGGGMGGGMGGHFDY

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family [H]

Homologues:

Organism=Homo sapiens, GI41399285, Length=98, Percent_Identity=35.7142857142857, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI31542947, Length=98, Percent_Identity=35.7142857142857, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790586, Length=89, Percent_Identity=47.1910112359551, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210679, Length=97, Percent_Identity=40.2061855670103, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555558, Length=97, Percent_Identity=40.2061855670103, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323288, Length=92, Percent_Identity=40.2173913043478, Blast_Score=71, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24641193, Length=107, Percent_Identity=31.7757009345794, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641191, Length=107, Percent_Identity=31.7757009345794, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17864606, Length=108, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550936, Length=107, Percent_Identity=35.5140186915888, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45550132, Length=107, Percent_Identity=35.5140186915888, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45550935, Length=107, Percent_Identity=35.5140186915888, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 14657; Mature: 14526

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAPGRRQQESLNELWVGRCNQNLSGEELIGANFVAQTLDALLKRIAENAGANGSVVAE
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
NVRHKPFSEGFNAASNEYVDMLAAGIIDPAKVTRSGLQNAASIAGMVLTTECIVVDLPEK
HHCCCCCHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCC
KEAAPAGGGMGGGMGGHFDY
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRAPGRRQQESLNELWVGRCNQNLSGEELIGANFVAQTLDALLKRIAENAGANGSVVAE
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
NVRHKPFSEGFNAASNEYVDMLAAGIIDPAKVTRSGLQNAASIAGMVLTTECIVVDLPEK
HHCCCCCHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCC
KEAAPAGGGMGGGMGGHFDY
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA