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The map label for this gene is ribE [H]

Identifier: 148241766

GI number: 148241766

Start: 605765

End: 606412

Strand: Direct

Name: ribE [H]

Synonym: SynRCC307_0667

Alternate gene names: 148241766

Gene position: 605765-606412 (Clockwise)

Preceding gene: 148241763

Following gene: 148241767

Centisome position: 27.23

GC content: 64.35

Gene sequence:

>648_bases
GTGTTCACCGGATTGGTCCAGGCCGTTGGCCGGCTGCAGTCGCTGCCGGATGCGGTGCGCGTTAGCTGGTCGCCGCAGCA
TTGGATGGCCGAGGGCTTGGCTGTGGGCGACAGCGTCGCCGTTGATGGGGTTTGCCTCACGGCGCGAAAGCTGTTGGAGC
ACGGCTTTGAAGCTGATGTCAGCCCCGAGACCTTGTCCCGCACCACCTTGGGGGAGCGGGCCCGCAGCGGCGCAGCCGTC
AATCTTGAGCCGGCCTTGCGCTTGGCCGATCGCCTCGGCGGCCATCTCGTTAGTGGCCATATCGATGGCTTGGGGCGGGT
CGAGGCGATCAGCCGCCAGGGTCACTCCTGGGATTTGCAGCTGGCTTGGGACGACCCCCGCTTGGGCCGCTACATCTGCG
AGAAGGGCAGCGTGGCCGTCAATGGCATCAGCCTCACGGTGGCGTCGTGCCATCCAGACGGCGTCAGCTTCAGCTTGGCC
GTGATCCCCCACACCTGGGAGCAAACGACACTGCAGGAGCTGCGCTGCGGTGATGCCGTCAATCTGGAAGCCGATTTGCT
CGCTAAATACGTGGAACGTCTCCTGCCTGGGTCGGCTTCAGCTGATCTGACGTCCCAGTGGATGGCCGAGAATGGTTGGA
ATGTCTAG

Upstream 100 bases:

>100_bases
GGCGGCATCGAGGGCGATGCCTGCAACGCTCATCTCCACCATCTGGTGGTGCTGGCTGCTGCGACGATTATGGCCAGATC
AGCCACGTGGTTACTGCTCA

Downstream 100 bases:

>100_bases
CTTTTGGGGGCGTCCCTCGCTCCCATGTTCAAATCATTCACGATCGCGGAGGGCATCCTGCTGATCGTTCTCGGCGTTCT
GGCTTTGATCGCTCCCATCA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MFTGLVQAVGRLQSLPDAVRVSWSPQHWMAEGLAVGDSVAVDGVCLTARKLLEHGFEADVSPETLSRTTLGERARSGAAV
NLEPALRLADRLGGHLVSGHIDGLGRVEAISRQGHSWDLQLAWDDPRLGRYICEKGSVAVNGISLTVASCHPDGVSFSLA
VIPHTWEQTTLQELRCGDAVNLEADLLAKYVERLLPGSASADLTSQWMAENGWNV

Sequences:

>Translated_215_residues
MFTGLVQAVGRLQSLPDAVRVSWSPQHWMAEGLAVGDSVAVDGVCLTARKLLEHGFEADVSPETLSRTTLGERARSGAAV
NLEPALRLADRLGGHLVSGHIDGLGRVEAISRQGHSWDLQLAWDDPRLGRYICEKGSVAVNGISLTVASCHPDGVSFSLA
VIPHTWEQTTLQELRCGDAVNLEADLLAKYVERLLPGSASADLTSQWMAENGWNV
>Mature_215_residues
MFTGLVQAVGRLQSLPDAVRVSWSPQHWMAEGLAVGDSVAVDGVCLTARKLLEHGFEADVSPETLSRTTLGERARSGAAV
NLEPALRLADRLGGHLVSGHIDGLGRVEAISRQGHSWDLQLAWDDPRLGRYICEKGSVAVNGISLTVASCHPDGVSFSLA
VIPHTWEQTTLQELRCGDAVNLEADLLAKYVERLLPGSASADLTSQWMAENGWNV

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=209, Percent_Identity=36.3636363636364, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=204, Percent_Identity=32.843137254902, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23102; Mature: 23102

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLVQAVGRLQSLPDAVRVSWSPQHWMAEGLAVGDSVAVDGVCLTARKLLEHGFEADV
CCHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHCCCCCCEECHHHHHHHHHHHCCCCCCC
SPETLSRTTLGERARSGAAVNLEPALRLADRLGGHLVSGHIDGLGRVEAISRQGHSWDLQ
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCEEEECCCCCCHHHHHHHCCCCCEEEE
LAWDDPRLGRYICEKGSVAVNGISLTVASCHPDGVSFSLAVIPHTWEQTTLQELRCGDAV
EEECCCHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHCCCCC
NLEADLLAKYVERLLPGSASADLTSQWMAENGWNV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MFTGLVQAVGRLQSLPDAVRVSWSPQHWMAEGLAVGDSVAVDGVCLTARKLLEHGFEADV
CCHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHCCCCCCEECHHHHHHHHHHHCCCCCCC
SPETLSRTTLGERARSGAAVNLEPALRLADRLGGHLVSGHIDGLGRVEAISRQGHSWDLQ
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCEEEECCCCCCHHHHHHHCCCCCEEEE
LAWDDPRLGRYICEKGSVAVNGISLTVASCHPDGVSFSLAVIPHTWEQTTLQELRCGDAV
EEECCCHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHCCCCC
NLEADLLAKYVERLLPGSASADLTSQWMAENGWNV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]