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The map label for this gene is glsA [H]

Identifier: 147674885

GI number: 147674885

Start: 3426

End: 4376

Strand: Direct

Name: glsA [H]

Synonym: VC0395_A0006

Alternate gene names: 147674885

Gene position: 3426-4376 (Clockwise)

Preceding gene: 147674960

Following gene: 147674559

Centisome position: 0.11

GC content: 51.42

Gene sequence:

>951_bases
TTGAGACAAACTAATAATAAAGAGTCAACCATGAAGCCAACAGCAGAGATTTTAGCCAGCATTATTGAAGAAGTTCGCCC
GCTCACTGGGCAGGGTAAAGTCGCCGATTACATTCCCGCACTCGCCAAAGTACCAAGTGAAAAGTTGGGCATCGCCGTAT
TCACCAACCAAGGGGAAGTGATCTCGGCCGGTGATGCGCAGGAAGGGTTTTCGATTCAGTCGATCTCCAAAGTGCTGAGC
TTGACGCTCGCGATGGGCTTATATCAGCCAAATGAACTGTGGAGCCGCGTGGGTAAAGAGCCTTCGGGGCAAGCATTTAA
CTCATTGATTCAGCTTGAGATGGAGCATGGAATTCCGCGTAATCCATTTATCAATGCCGGCGCGATTGTGGTGTGCGACA
TGCTGCAAAGTCGCCTCTCTGCACCTCGTCAGCGTCTGTTGGAGTTTGTACGCCAACTCAGCGGTGAGCCGCTCATTGCT
TATGACAAAGTCGTGGCAGCATCGGAGATGATGCACAGTGATCGCAACGCGGCGATTGCCTATTTGATGCGTTCTTTTGG
CAATTTCCACAATGAGGTTATTCCGGTACTGCACAACTATTTTCACGCCTGCGCATTGAAAATGAGCTGTGTTGAGCTGG
CGAAAACCTTCAGCTATCTTGCCAACAAAGGTGTTTCTGTGGTGACGGGGGAAACGGTGATCACCCCAACCCAAAGCAAA
CAAACCAATGCCTTACTCGCCACGTGCGGCTTGTATGATGGGGCAGGAGAATTTGCCTATCGAGTTGGTATGCCCGGAAA
ATCAGGTGTTGGCGGTGGGATTATTGCTGTGGTGCCGGGAGAAATGACGATTGCAGTGTGGTCCCCCGCGCTGGATCAAT
CGGGTAACTCGCTCGCGGGGACTCGCGCGTTAGAGTTACTCGCGCAGCGGATTGGTCGCTCAATTTTCTAA

Upstream 100 bases:

>100_bases
CAACTCCAAGTAGTTTGGGTATAGAGAATTTTGCTTAAGCCAACATTTGATGTTGGCTTTTTTGACCCTAATCCTCGAGC
TATTGAACAGCTGAAGTAGC

Downstream 100 bases:

>100_bases
GCTATCCCCTTTCTACTTGAAGCTGCAGCGGTGTTGGCAGCATTCGCTCACCCCAATCACATAGTGGATCTATGCTCATG
GGGATTATGAGAGCCATCCT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRQTNNKESTMKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEVISAGDAQEGFSIQSISKVLS
LTLAMGLYQPNELWSRVGKEPSGQAFNSLIQLEMEHGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIA
YDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSK
QTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF

Sequences:

>Translated_316_residues
MRQTNNKESTMKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEVISAGDAQEGFSIQSISKVLS
LTLAMGLYQPNELWSRVGKEPSGQAFNSLIQLEMEHGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIA
YDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSK
QTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF
>Mature_316_residues
MRQTNNKESTMKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEVISAGDAQEGFSIQSISKVLS
LTLAMGLYQPNELWSRVGKEPSGQAFNSLIQLEMEHGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIA
YDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSK
QTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=273, Percent_Identity=37.3626373626374, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI20336214, Length=285, Percent_Identity=35.7894736842105, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1787804, Length=300, Percent_Identity=67.6666666666667, Blast_Score=426, Evalue=1e-121,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=39.8601398601399, Blast_Score=201, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17507019, Length=300, Percent_Identity=37.3333333333333, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17532727, Length=294, Percent_Identity=34.3537414965986, Blast_Score=180, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI193204073, Length=295, Percent_Identity=35.9322033898305, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI193204075, Length=297, Percent_Identity=35.6902356902357, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=36.140350877193, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33948; Mature: 33948

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQTNNKESTMKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEV
CCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHCCEEEEECCCCE
ISAGDAQEGFSIQSISKVLSLTLAMGLYQPNELWSRVGKEPSGQAFNSLIQLEMEHGIPR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
NPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIAYDKVVAASEMMHSDRNAAIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHH
YLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCCC
QTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAG
CCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHH
TRALELLAQRIGRSIF
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRQTNNKESTMKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEV
CCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHCCEEEEECCCCE
ISAGDAQEGFSIQSISKVLSLTLAMGLYQPNELWSRVGKEPSGQAFNSLIQLEMEHGIPR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
NPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIAYDKVVAASEMMHSDRNAAIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHH
YLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCCC
QTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAG
CCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHH
TRALELLAQRIGRSIF
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA