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The map label for this gene is fabZ

Identifier: 147674767

GI number: 147674767

Start: 1957328

End: 1957789

Strand: Reverse

Name: fabZ

Synonym: VC0395_A1840

Alternate gene names: 147674767

Gene position: 1957789-1957328 (Counterclockwise)

Preceding gene: 147675586

Following gene: 147674688

Centisome position: 64.74

GC content: 44.59

Gene sequence:

>462_bases
ATGATGACTTTGACTACTGATAAGAAAACGATGAATATCACTGAAATTCAATCGCTTCTGCCTCACCGCTATCCATTTTT
ACTGATTGATCGCGTGACCGACTATGAAGAAGGTAAGTACCTGATTGGTTTGAAAAATGTTTCAGTGAATGAGCCTCAGT
TTACGGGTCACTTTCCACAACTGCCGGTTTTCCCCGGTGTATTGATTTTAGAAGCCATGGCTCAAGCCACTGGTCTGTTG
GCGTTCAAAACCTTTGGTGCGCCAAAAGAGAATGAACTGTACTATTTTGCCAGCATTGATGAAGCTAAGTTCCGTAAGCC
AGTGACACCGGGCGATCAACTGATGATTGAAGTTGAATTCCTTAAAGAGCGTCGTGGTATCGCGCTGTTTAACGGCGTGG
CCAAAGTCGATGGTGATGTGGTCTGTTCTGCTCAACTGAAATGCGCACGTCGAGAGTTTTAA

Upstream 100 bases:

>100_bases
GCCCGATAACTCTCAAGCTGAATAAGCTGGTTTCAAAGGCTCGCACATTGCGAGTCTTTTCGCTGTTGGGTATTCCCTTA
TTTTTCTATTTACAAACAGG

Downstream 100 bases:

>100_bases
GATGATTCACGAAACTGCACAAATTCACCCAACTTCCGTCGTGGAAGAGGGCGCTATCATTGGTGCCAACGTTAAGATTG
GTCCTTTCTGTTTTGTCGAT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MMTLTTDKKTMNITEIQSLLPHRYPFLLIDRVTDYEEGKYLIGLKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLL
AFKTFGAPKENELYYFASIDEAKFRKPVTPGDQLMIEVEFLKERRGIALFNGVAKVDGDVVCSAQLKCARREF

Sequences:

>Translated_153_residues
MMTLTTDKKTMNITEIQSLLPHRYPFLLIDRVTDYEEGKYLIGLKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLL
AFKTFGAPKENELYYFASIDEAKFRKPVTPGDQLMIEVEFLKERRGIALFNGVAKVDGDVVCSAQLKCARREF
>Mature_153_residues
MMTLTTDKKTMNITEIQSLLPHRYPFLLIDRVTDYEEGKYLIGLKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLL
AFKTFGAPKENELYYFASIDEAKFRKPVTPGDQLMIEVEFLKERRGIALFNGVAKVDGDVVCSAQLKCARREF

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=147, Percent_Identity=64.6258503401361, Blast_Score=204, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_VIBC3 (A5F629)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F629
- SMR:   A5F629
- STRING:   A5F629
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1840
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   VCHO345073:VC0395_A1840-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17292; Mature: 17292

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLTTDKKTMNITEIQSLLPHRYPFLLIDRVTDYEEGKYLIGLKNVSVNEPQFTGHFPQ
CCEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCC
LPVFPGVLILEAMAQATGLLAFKTFGAPKENELYYFASIDEAKFRKPVTPGDQLMIEVEF
CCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEECCHHHHCCCCCCCCCEEEEEEH
LKERRGIALFNGVAKVDGDVVCSAQLKCARREF
HHCCCCEEEECCEECCCCCEEEEHHHHHHCCCC
>Mature Secondary Structure
MMTLTTDKKTMNITEIQSLLPHRYPFLLIDRVTDYEEGKYLIGLKNVSVNEPQFTGHFPQ
CCEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCC
LPVFPGVLILEAMAQATGLLAFKTFGAPKENELYYFASIDEAKFRKPVTPGDQLMIEVEF
CCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEECCHHHHCCCCCCCCCEEEEEEH
LKERRGIALFNGVAKVDGDVVCSAQLKCARREF
HHCCCCEEEECCEECCCCCEEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA