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The map label for this gene is cdsA [H]

Identifier: 147674661

GI number: 147674661

Start: 1964526

End: 1965368

Strand: Reverse

Name: cdsA [H]

Synonym: VC0395_A1846

Alternate gene names: 147674661

Gene position: 1965368-1964526 (Counterclockwise)

Preceding gene: 147675134

Following gene: 147674244

Centisome position: 64.99

GC content: 48.16

Gene sequence:

>843_bases
TTGAAGCAGCGAATCATTACAGCGCTTATTCTGGCGCCTTTGGTGATCCTTGGCATCCTTTATCTGCCTTTTGCTTGGTT
TATGTTGGCACTCGCAGTAGTGACCTTACTCGGATTCTGGGAATGGACTCAGTTCGTTAACCAACCATCACGCATGTTAG
CCATGATTCCCGCCTTATTGGTTGGTGGTATCAGTGTCGCTTTGATCGACTTTCAATTTCCGGCTATCAGCAATATGAAT
ACGGCGCATTTTATTGTGCTGGGTATCGGTAGCCTTTGGTGGCTCGTCTCAAGTGGACTGGCGATCACTTATCCGCGCTC
GCGTCCATTATGGGAGCACTCCAGCACTGTTCGCCACCTGTTTGGCCTATTTACGCTGCTGCCTTTCTTTTGGAGTGTGT
TGTTCTTACGCGCCGATACTTACCTTTCCGATCCTCTTTATGGTGCGAAATTAGTTCTCTTCGTCTGTTTTCTGGTCTGG
GCCGCAGACAGCGGTGCCTATTTTGTGGGAAAAAGCTTAGGTAAACACAAAATGGCGCCCGCAGTCAGCCCGAATAAAAC
GATAGAAGGTTTGGTCGGTGGCATCGTCACCGCCATGCTGGTTGGTTATTGGGTAGCAGAGTGCTTTGGTATTCAATTTA
GCTCTATGCCTGTCATGCTGCTGATCATCTTATTGACTGTGGTAATTTCGGTTTTAGGGGATTTGGTCGAGAGCATGTTT
AAACGTGTTTCTGGGATCAAAGACAGCAGCAATATCATTCCTGGGCACGGCGGCATTCTGGATCGGATTGATAGCCTAAC
GGCCGCTTTCCCTGTGTTCGCTCTTCTCTATTTCTTGTTCTAG

Upstream 100 bases:

>100_bases
TTGAAGCAGTGACTTGGTTTGTTAATCGTGAGCGCCGTTTTGGCTGTACTGGTGAACAAGTCAAGGCATTGATGGAAAAC
TGAATATAGGACTTCTCAAT

Downstream 100 bases:

>100_bases
TACTCAGGCTGCTTAGGCAGCCTGATGTGAATAACAGCGATCTTCACTATGCGTAAACTAACCATTTTAGGTGCCACAGG
TTCGATAGGAGCCAGCACCC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKQRIITALILAPLVILGILYLPFAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALLVGGISVALIDFQFPAISNMN
TAHFIVLGIGSLWWLVSSGLAITYPRSRPLWEHSSTVRHLFGLFTLLPFFWSVLFLRADTYLSDPLYGAKLVLFVCFLVW
AADSGAYFVGKSLGKHKMAPAVSPNKTIEGLVGGIVTAMLVGYWVAECFGIQFSSMPVMLLIILLTVVISVLGDLVESMF
KRVSGIKDSSNIIPGHGGILDRIDSLTAAFPVFALLYFLF

Sequences:

>Translated_280_residues
MKQRIITALILAPLVILGILYLPFAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALLVGGISVALIDFQFPAISNMN
TAHFIVLGIGSLWWLVSSGLAITYPRSRPLWEHSSTVRHLFGLFTLLPFFWSVLFLRADTYLSDPLYGAKLVLFVCFLVW
AADSGAYFVGKSLGKHKMAPAVSPNKTIEGLVGGIVTAMLVGYWVAECFGIQFSSMPVMLLIILLTVVISVLGDLVESMF
KRVSGIKDSSNIIPGHGGILDRIDSLTAAFPVFALLYFLF
>Mature_280_residues
MKQRIITALILAPLVILGILYLPFAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALLVGGISVALIDFQFPAISNMN
TAHFIVLGIGSLWWLVSSGLAITYPRSRPLWEHSSTVRHLFGLFTLLPFFWSVLFLRADTYLSDPLYGAKLVLFVCFLVW
AADSGAYFVGKSLGKHKMAPAVSPNKTIEGLVGGIVTAMLVGYWVAECFGIQFSSMPVMLLIILLTVVISVLGDLVESMF
KRVSGIKDSSNIIPGHGGILDRIDSLTAAFPVFALLYFLF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=283, Percent_Identity=44.1696113074205, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787677, Length=113, Percent_Identity=41.5929203539823, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30868; Mature: 30868

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRIITALILAPLVILGILYLPFAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VGGISVALIDFQFPAISNMNTAHFIVLGIGSLWWLVSSGLAITYPRSRPLWEHSSTVRHL
HCCHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
FGLFTLLPFFWSVLFLRADTYLSDPLYGAKLVLFVCFLVWAADSGAYFVGKSLGKHKMAP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHCCC
AVSPNKTIEGLVGGIVTAMLVGYWVAECFGIQFSSMPVMLLIILLTVVISVLGDLVESMF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KRVSGIKDSSNIIPGHGGILDRIDSLTAAFPVFALLYFLF
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKQRIITALILAPLVILGILYLPFAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VGGISVALIDFQFPAISNMNTAHFIVLGIGSLWWLVSSGLAITYPRSRPLWEHSSTVRHL
HCCHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
FGLFTLLPFFWSVLFLRADTYLSDPLYGAKLVLFVCFLVWAADSGAYFVGKSLGKHKMAP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHCCC
AVSPNKTIEGLVGGIVTAMLVGYWVAECFGIQFSSMPVMLLIILLTVVISVLGDLVESMF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KRVSGIKDSSNIIPGHGGILDRIDSLTAAFPVFALLYFLF
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]