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The map label for this gene is yaeL [C]

Identifier: 147673634

GI number: 147673634

Start: 1961914

End: 1963272

Strand: Reverse

Name: yaeL [C]

Synonym: VC0395_A1844

Alternate gene names: 147673634

Gene position: 1963272-1961914 (Counterclockwise)

Preceding gene: 147674244

Following gene: 147675293

Centisome position: 64.92

GC content: 48.57

Gene sequence:

>1359_bases
ATGACCGACATATTGTGGAACTTTATCGCCTTCATCATTGCGCTGGGCATTCTCGTCGCAGTGCATGAGTTCGGACACTT
CTGGGTTGCCAGACGTTGCGGTGTGAAAGTTGAGAAATTTTCTATCGGTTTTGGGAAATCGATTTGGAAACGCGTCGGCC
ATGACGGTACAGAATACTCGATATCGATGATCCCACTCGGTGGTTACGTCAAAATGCTCGATGGACGTGTGGATGATGTT
CCCGCCGAACAGCAAGCCATGGCGTTTGATAAGCAGTCACTCTGGAAACGTTCTGCCATTGTGAGTGCGGGCCCCATTTT
TAACTTCCTCTTCGCAATCTTTGCCTATTGGCTGGTGTTTATGATCGGCGTACCAGCGGTCAAGCCTGTGATTGGCGAAG
TGACACCCTACTCGATTGCGGCTCAAGCGGGCCTTGAGCCGGGTATGGAGATCAAAGCGGTTTCTGGCGTGAATACTCCC
GACTGGGAATCGGTCAACATGGGCTTAATTGGTCATATTGGCGATGACAGTATGACGATCACCGTCTCCTCCGCCGAAGG
GGTGGGATTGAATGAAATTAAGACAATAAATCTGCGTGATTGGAACTTTGACCCAGAAACAGAGTCTGCTATGGGGGCGC
TTGGCTTTAAACCTTTTACCCCTGAGATTTCCAATCAGCTGACCAATGTTTCTGCGCAAGGTGCGGGTGAGCGTGCGGGT
TTACAAGTCGGTGATACCGTGTTGCAAATCAATGGACAAGCGGTTGAGGCTTGGCAACAAGTGGTCAATGCAATTCAAAG
TCATCCTAACGCGCCTATCGCAGTTATGGTTGAGCGAGCAGGCCAGCAAGTTGAACTCACTTTGATTCCCGATAGCCGTG
AGCTTTCGCAAGGAAAAGTGATTGGTTTTGCGGGAATCGCACCAAAAGTCGCAGAATGGCCGCAAAACTATCGATTTGAA
TTGCAATTTGGTGTATTTGAGTCGCTTGGTAAAGCGGTTGAAAAAAGCGGACAAGTGATTGACCTGACGGTCAGCATGTT
GAAAAAACTGTTGGTGGGCGATGTTGGGTTGAATAATCTCAGTGGTCCCATTTCGATTGCTAAAGGCGCAGGAACAACGG
CTGACTACGGCTTTGTGTACTTTTTAGGCTTTTTGGCTCTGATCAGTATTAACCTTGGCATTATCAACTTGGTGCCACTG
CCGATGCTGGATGGTGGTCATCTGTTGTTTTTCATGATTGAAGCGGTGATCCGTCGCCCTGTTCCGGAAAAGGTGCAGGA
AATGGGTTACCGGATTGGTGGTGCCATCATTTTCTCTTTAATGGCCGTTGCAATCTTTAACGATTTTACTCACCTGTGA

Upstream 100 bases:

>100_bases
CGACCAACACCCAGTTACATTGCCGTGACTTGGAAAGCCTGCTTGAGCTAGATACAATGGCTCGGCATTTTGCCCATCAA
GTACTCAAAGAGCGCCAAGC

Downstream 100 bases:

>100_bases
TTGATAAACATTAGGCAAGAGTTGCAGTAAGGAAGAACTCAAAACAATATGGCGATGAAACAGATTCTGCTCGCGACACT
GCTTGCCACGAGCGTGTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGGYVKMLDGRVDDV
PAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVFMIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTP
DWESVNMGLIGHIGDDSMTITVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKVIGFAGIAPKVAEWPQNYRFE
LQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNLSGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPL
PMLDGGHLLFFMIEAVIRRPVPEKVQEMGYRIGGAIIFSLMAVAIFNDFTHL

Sequences:

>Translated_452_residues
MTDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGGYVKMLDGRVDDV
PAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVFMIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTP
DWESVNMGLIGHIGDDSMTITVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKVIGFAGIAPKVAEWPQNYRFE
LQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNLSGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPL
PMLDGGHLLFFMIEAVIRRPVPEKVQEMGYRIGGAIIFSLMAVAIFNDFTHL
>Mature_451_residues
TDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGGYVKMLDGRVDDVP
AEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVFMIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTPD
WESVNMGLIGHIGDDSMTITVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAGL
QVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKVIGFAGIAPKVAEWPQNYRFEL
QFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNLSGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPLP
MLDGGHLLFFMIEAVIRRPVPEKVQEMGYRIGGAIIFSLMAVAIFNDFTHL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=452, Percent_Identity=53.0973451327434, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48963; Mature: 48832

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCEE
ISMIPLGGYVKMLDGRVDDVPAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVF
EEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTPDWESVNMGLIGHIGDDSMTI
HHCCCHHHHHHCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
TVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
EEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKV
CEECCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCE
IGFAGIAPKVAEWPQNYRFELQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNL
EEEECCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCC
SGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPLPMLDGGHLLFFMIEAVIRRP
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
VPEKVQEMGYRIGGAIIFSLMAVAIFNDFTHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDILWNFIAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCEE
ISMIPLGGYVKMLDGRVDDVPAEQQAMAFDKQSLWKRSAIVSAGPIFNFLFAIFAYWLVF
EEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MIGVPAVKPVIGEVTPYSIAAQAGLEPGMEIKAVSGVNTPDWESVNMGLIGHIGDDSMTI
HHCCCHHHHHHCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
TVSSAEGVGLNEIKTINLRDWNFDPETESAMGALGFKPFTPEISNQLTNVSAQGAGERAG
EEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
LQVGDTVLQINGQAVEAWQQVVNAIQSHPNAPIAVMVERAGQQVELTLIPDSRELSQGKV
CEECCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCE
IGFAGIAPKVAEWPQNYRFELQFGVFESLGKAVEKSGQVIDLTVSMLKKLLVGDVGLNNL
EEEECCCCHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCC
SGPISIAKGAGTTADYGFVYFLGFLALISINLGIINLVPLPMLDGGHLLFFMIEAVIRRP
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
VPEKVQEMGYRIGGAIIFSLMAVAIFNDFTHL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]