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The map label for this gene is mtnA [H]

Identifier: 146343661

GI number: 146343661

Start: 7174136

End: 7175242

Strand: Reverse

Name: mtnA [H]

Synonym: BRADO6903

Alternate gene names: 146343661

Gene position: 7175242-7174136 (Counterclockwise)

Preceding gene: 146343662

Following gene: 146343659

Centisome position: 96.23

GC content: 68.65

Gene sequence:

>1107_bases
ATGAAGGTGGACGGCAAGCATTATCGCAGCATATGGCTCGATGCCGACGGCTGGACGGTCTGTGCGATCGATCAGCGGCG
GCTGCCGCACGAGTTCGTGGTCGCGCAGATCACCACCTGCGAGGAGGCGGCGGATGCCATCCGCCACATGCTGGTGCGCG
GCGCGCCGCTGATCGGCGCTACTGCGGCGTTCGGCATGGCGCTGGCGATGCGCGACGACCGCTCCGATCCCGGCATCGAG
CGCGCCTATGAGATGCTGATCGCGACACGGCCGACCGCGATCAATCTGAAATGGGCGCTCGATACGATGGCCACGATGCT
GCGCCGCCTCGCGCCGTCGGAGCGGCGGGATGCGGCGTATTCGCGCGCGGTGGACATCGCCGGCGAGGACGTCACGATCA
ACCAGGGCATCGCCGCACATGGTCTCGCGCTGATCGAAGCGGCGGCCGCGCGCAAGACGCCGGGCGAGGTCGTGAACGTG
CTGACGCATTGCAATGCCGGCTGGCTCGCGACCGTCGATTGGGGCACGGCCACCGCGCCGATCTATCTCGCTCACGATCG
CGGCATTCCGGTCCATGTCTGGGTCGACGAGACGCGGCCGCGCAACCAGGGCGCCTCGCTGACCGCCTGGGAGCTCGGCC
ATCACGGCGTGGCGCACACCGTGATCCCGGACAATACCGGCGGCCATCTGATGCAGCATGGCATGGTCGATCTCGCCATC
GTCGGCACCGACCGCGTCGCCGCCAATGGCGACGTCTGCAACAAGATCGGCACCTATCTCAAGGCGTTGGCGGCCCACGA
TAATGGCGTGCCGTTCTACGTCGCGCTGCCGTCGCCGACGATCGACTTCGCCGTCGCCGAGGGCCGGCAGATCCCGATCG
AGCAGCGCAGCGCGCAGGAGGTCACGGAGATGACTGGCCGCACCGCCGATGGCCGCATCGAGACCGTGCGCATCGTGCCG
CCGGGCTCGCAGGTCGCGAACTACGGCTTCGACGTCACGCCGGCGCGGCTGGTGACGGGACTGATCACGGAGCGCGGCGT
GTTGCAGGCGGACGGCGCCGCGCTTGCGGCGGCGTTTCCGGAACGGGCGAAGCCCACGAACGATTAG

Upstream 100 bases:

>100_bases
ACCGCGTTGATCACGGCGCCTGAGGCGCGCGATCCCGAACTCCTCAAGAAGCTCGATGCGGTCGCTGGCCGCCTTCTGCG
CGGCTGACGGGAGATCGACG

Downstream 100 bases:

>100_bases
ATCATCGTCATTAGGATCGACGCGCCGGCCGCTCGCGTTCGCGAGGCGACTATGTCAGCTTCAGCCCCGTCGCGGCCTCG
AGTTCGGTGATCACCTGTGA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKVDGKHYRSIWLDADGWTVCAIDQRRLPHEFVVAQITTCEEAADAIRHMLVRGAPLIGATAAFGMALAMRDDRSDPGIE
RAYEMLIATRPTAINLKWALDTMATMLRRLAPSERRDAAYSRAVDIAGEDVTINQGIAAHGLALIEAAAARKTPGEVVNV
LTHCNAGWLATVDWGTATAPIYLAHDRGIPVHVWVDETRPRNQGASLTAWELGHHGVAHTVIPDNTGGHLMQHGMVDLAI
VGTDRVAANGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDFAVAEGRQIPIEQRSAQEVTEMTGRTADGRIETVRIVP
PGSQVANYGFDVTPARLVTGLITERGVLQADGAALAAAFPERAKPTND

Sequences:

>Translated_368_residues
MKVDGKHYRSIWLDADGWTVCAIDQRRLPHEFVVAQITTCEEAADAIRHMLVRGAPLIGATAAFGMALAMRDDRSDPGIE
RAYEMLIATRPTAINLKWALDTMATMLRRLAPSERRDAAYSRAVDIAGEDVTINQGIAAHGLALIEAAAARKTPGEVVNV
LTHCNAGWLATVDWGTATAPIYLAHDRGIPVHVWVDETRPRNQGASLTAWELGHHGVAHTVIPDNTGGHLMQHGMVDLAI
VGTDRVAANGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDFAVAEGRQIPIEQRSAQEVTEMTGRTADGRIETVRIVP
PGSQVANYGFDVTPARLVTGLITERGVLQADGAALAAAFPERAKPTND
>Mature_368_residues
MKVDGKHYRSIWLDADGWTVCAIDQRRLPHEFVVAQITTCEEAADAIRHMLVRGAPLIGATAAFGMALAMRDDRSDPGIE
RAYEMLIATRPTAINLKWALDTMATMLRRLAPSERRDAAYSRAVDIAGEDVTINQGIAAHGLALIEAAAARKTPGEVVNV
LTHCNAGWLATVDWGTATAPIYLAHDRGIPVHVWVDETRPRNQGASLTAWELGHHGVAHTVIPDNTGGHLMQHGMVDLAI
VGTDRVAANGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDFAVAEGRQIPIEQRSAQEVTEMTGRTADGRIETVRIVP
PGSQVANYGFDVTPARLVTGLITERGVLQADGAALAAAFPERAKPTND

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=341, Percent_Identity=38.41642228739, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI23943880, Length=334, Percent_Identity=34.7305389221557, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17557462, Length=338, Percent_Identity=33.4319526627219, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6325375, Length=386, Percent_Identity=28.2383419689119, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357667, Length=344, Percent_Identity=37.5, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24651647, Length=344, Percent_Identity=37.5, Blast_Score=191, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39519; Mature: 39519

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDGKHYRSIWLDADGWTVCAIDQRRLPHEFVVAQITTCEEAADAIRHMLVRGAPLIGA
CCCCCCEEEEEEEECCCCEEEEECCCCCCCHHEEEEEHHHHHHHHHHHHHHHHCCCCEEH
TAAFGMALAMRDDRSDPGIERAYEMLIATRPTAINLKWALDTMATMLRRLAPSERRDAAY
HHHHHEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHH
SRAVDIAGEDVTINQGIAAHGLALIEAAAARKTPGEVVNVLTHCNAGWLATVDWGTATAP
HHHEECCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
IYLAHDRGIPVHVWVDETRPRNQGASLTAWELGHHGVAHTVIPDNTGGHLMQHGMVDLAI
EEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHCCCEEEEE
VGTDRVAANGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDFAVAEGRQIPIEQRSAQE
EECCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHH
VTEMTGRTADGRIETVRIVPPGSQVANYGFDVTPARLVTGLITERGVLQADGAALAAAFP
HHHHHCCCCCCCEEEEEEECCCHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCCHHHCCC
ERAKPTND
CCCCCCCC
>Mature Secondary Structure
MKVDGKHYRSIWLDADGWTVCAIDQRRLPHEFVVAQITTCEEAADAIRHMLVRGAPLIGA
CCCCCCEEEEEEEECCCCEEEEECCCCCCCHHEEEEEHHHHHHHHHHHHHHHHCCCCEEH
TAAFGMALAMRDDRSDPGIERAYEMLIATRPTAINLKWALDTMATMLRRLAPSERRDAAY
HHHHHEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHH
SRAVDIAGEDVTINQGIAAHGLALIEAAAARKTPGEVVNVLTHCNAGWLATVDWGTATAP
HHHEECCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
IYLAHDRGIPVHVWVDETRPRNQGASLTAWELGHHGVAHTVIPDNTGGHLMQHGMVDLAI
EEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHHHCCCEEEEE
VGTDRVAANGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDFAVAEGRQIPIEQRSAQE
EECCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHH
VTEMTGRTADGRIETVRIVPPGSQVANYGFDVTPARLVTGLITERGVLQADGAALAAAFP
HHHHHCCCCCCCEEEEEEECCCHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCCHHHCCC
ERAKPTND
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA