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The map label for this gene is yisK [H]

Identifier: 146342342

GI number: 146342342

Start: 5679976

End: 5680965

Strand: Reverse

Name: yisK [H]

Synonym: BRADO5498

Alternate gene names: 146342342

Gene position: 5680965-5679976 (Counterclockwise)

Preceding gene: 146342348

Following gene: 146342341

Centisome position: 76.19

GC content: 67.07

Gene sequence:

>990_bases
GTGAAGCTTGCGACATTTCGAACCGAGGGCCGGGAGCGGATCGGCGTGGTCCACGCCGGTGATTCCCGGCTCTTCGATCT
GGCAGCCGCCGCCGATCGCGCCGGCAAAACCAACCCGGCCTTCGCCTCGATGCTGTCGCTGATCGATGCCGGCGACGCCG
CGCTCGACGAGGCCCGCGCGCTGATCGAGCGCTATGGCGGCGACGAGAGCCTGTCGCGAGATGCCGCGGGCACGGAGCTG
CTGGCACCGGTGCCGGAGCCGCGGCAGATGCGCGACGGCATGTCGTTTCCGCTGCACATCCTCCAGGCGCCGCGCGGCCA
GCGCAAGCTCGCGGCGCGCCAGCGCGGCGACACCGAGGAGCTCGCGCGCATCGATGCCGAGCCGCTCGGCGAACTGCCCG
AGGTTTATCGCAAGGTCCCGATCTTCTACATCACCAACCGGTTCAGCGTGCGCGGTCCCAACACGGTCGTGACATGGCCG
CGCTACAGCCAGGTGATGGACTACGAGCTGGAGTTCGGCATCATCACGAAGGGCCGGGGCAAGGACATTGCGGCCGGCAA
GGCGGGCGACCACATCTTCGGCTTCACCATCTTCAATGACTTCTCCGCCCGCGACACGCAGCGCGTCGAGATGGACGGCC
GCCTCGGTCCCTCCAAGGGCAAGAGCTTCGACGGCGGCAACGTCATGGGGCCGTGGATCGTGACGCCCGACGAGATCGGC
GATCCCTATCGCCTGAAGATGGAGGCGCGCGTCAATGGCGCGGTCCGCTCGCGCGGCGTCAGCGAGGGCATGCTGTTCTC
GTTCGAGGAGCTGATCGCCTATATCAGCAAGGACGAGACATTGATGCCGGGCGAGTTCATCGGGTCGGGCACGGTCGGCA
ATGGCTGCGGGCTCGAGCTCGGCTGGTACCTCGAGCATGGCGACGTCATCGAGCTCGAGGTCGAGAAGATCGGCATCCTG
AAGAACAGGGTCGAGCGGCAGGACGTCTGA

Upstream 100 bases:

>100_bases
TGGTTGATGTCCTCCCCCGGGGATTGGCCCGTTCGGCCTCTTGTTTATCGATATTTTCTATGATTGTATATTTTGTAAGA
AAACACAAGGGGAGGCCGGC

Downstream 100 bases:

>100_bases
CACGACCGGCGATGACAACCAAGAACGACAAGAGAGAGGACCGCCCATGGCCCGCAAGCTGATCGACATCTCCGTGCCGC
TGCAGAACGACGTGCCGGCC

Product: putative fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKLATFRTEGRERIGVVHAGDSRLFDLAAAADRAGKTNPAFASMLSLIDAGDAALDEARALIERYGGDESLSRDAAGTEL
LAPVPEPRQMRDGMSFPLHILQAPRGQRKLAARQRGDTEELARIDAEPLGELPEVYRKVPIFYITNRFSVRGPNTVVTWP
RYSQVMDYELEFGIITKGRGKDIAAGKAGDHIFGFTIFNDFSARDTQRVEMDGRLGPSKGKSFDGGNVMGPWIVTPDEIG
DPYRLKMEARVNGAVRSRGVSEGMLFSFEELIAYISKDETLMPGEFIGSGTVGNGCGLELGWYLEHGDVIELEVEKIGIL
KNRVERQDV

Sequences:

>Translated_329_residues
MKLATFRTEGRERIGVVHAGDSRLFDLAAAADRAGKTNPAFASMLSLIDAGDAALDEARALIERYGGDESLSRDAAGTEL
LAPVPEPRQMRDGMSFPLHILQAPRGQRKLAARQRGDTEELARIDAEPLGELPEVYRKVPIFYITNRFSVRGPNTVVTWP
RYSQVMDYELEFGIITKGRGKDIAAGKAGDHIFGFTIFNDFSARDTQRVEMDGRLGPSKGKSFDGGNVMGPWIVTPDEIG
DPYRLKMEARVNGAVRSRGVSEGMLFSFEELIAYISKDETLMPGEFIGSGTVGNGCGLELGWYLEHGDVIELEVEKIGIL
KNRVERQDV
>Mature_329_residues
MKLATFRTEGRERIGVVHAGDSRLFDLAAAADRAGKTNPAFASMLSLIDAGDAALDEARALIERYGGDESLSRDAAGTEL
LAPVPEPRQMRDGMSFPLHILQAPRGQRKLAARQRGDTEELARIDAEPLGELPEVYRKVPIFYITNRFSVRGPNTVVTWP
RYSQVMDYELEFGIITKGRGKDIAAGKAGDHIFGFTIFNDFSARDTQRVEMDGRLGPSKGKSFDGGNVMGPWIVTPDEIG
DPYRLKMEARVNGAVRSRGVSEGMLFSFEELIAYISKDETLMPGEFIGSGTVGNGCGLELGWYLEHGDVIELEVEKIGIL
KNRVERQDV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=188, Percent_Identity=37.7659574468085, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI40786394, Length=190, Percent_Identity=37.3684210526316, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI215422413, Length=152, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI66348062, Length=152, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI13654274, Length=152, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=27.3743016759777, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28572127, Length=188, Percent_Identity=29.2553191489362, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24663695, Length=186, Percent_Identity=28.494623655914, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 36215; Mature: 36215

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLATFRTEGRERIGVVHAGDSRLFDLAAAADRAGKTNPAFASMLSLIDAGDAALDEARA
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHH
LIERYGGDESLSRDAAGTELLAPVPEPRQMRDGMSFPLHILQAPRGQRKLAARQRGDTEE
HHHHHCCCHHHCCCCCCCEEECCCCCHHHHHCCCCCCHHEECCCCCHHHHHHHHCCCHHH
LARIDAEPLGELPEVYRKVPIFYITNRFSVRGPNTVVTWPRYSQVMDYELEFGIITKGRG
HHHCCCCHHHHHHHHHHHCCEEEEECEEEECCCCEEEECCCHHHHCCEEEEEEEEECCCC
KDIAAGKAGDHIFGFTIFNDFSARDTQRVEMDGRLGPSKGKSFDGGNVMGPWIVTPDEIG
CCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECHHHCC
DPYRLKMEARVNGAVRSRGVSEGMLFSFEELIAYISKDETLMPGEFIGSGTVGNGCGLEL
CCEEEEEEEHHCHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCEE
GWYLEHGDVIELEVEKIGILKNRVERQDV
EEEECCCCEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLATFRTEGRERIGVVHAGDSRLFDLAAAADRAGKTNPAFASMLSLIDAGDAALDEARA
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHH
LIERYGGDESLSRDAAGTELLAPVPEPRQMRDGMSFPLHILQAPRGQRKLAARQRGDTEE
HHHHHCCCHHHCCCCCCCEEECCCCCHHHHHCCCCCCHHEECCCCCHHHHHHHHCCCHHH
LARIDAEPLGELPEVYRKVPIFYITNRFSVRGPNTVVTWPRYSQVMDYELEFGIITKGRG
HHHCCCCHHHHHHHHHHHCCEEEEECEEEECCCCEEEECCCHHHHCCEEEEEEEEECCCC
KDIAAGKAGDHIFGFTIFNDFSARDTQRVEMDGRLGPSKGKSFDGGNVMGPWIVTPDEIG
CCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECHHHCC
DPYRLKMEARVNGAVRSRGVSEGMLFSFEELIAYISKDETLMPGEFIGSGTVGNGCGLEL
CCEEEEEEEHHCHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCEE
GWYLEHGDVIELEVEKIGILKNRVERQDV
EEEECCCCEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]