Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 146341680

GI number: 146341680

Start: 4979500

End: 4980510

Strand: Reverse

Name: livH [H]

Synonym: BRADO4785

Alternate gene names: 146341680

Gene position: 4980510-4979500 (Counterclockwise)

Preceding gene: 146341681

Following gene: 146341679

Centisome position: 66.79

GC content: 64.69

Gene sequence:

>1011_bases
ATGAGCCGCTTCATCGAACGTCACCCGATCTGGTCTCTCGTCATTCTCATCGCCATCGCGTGCCTCGCATGGCTGATCAT
CGCCGTCTGGCCGCCGGGTCTGGAGGACGCGATCGGCCGCAAAAAGGTCTTTCTCAGCGCCGTCTTCAACGGCATCACGC
TCGGCGGACTCTACTTCCTGGTCGCGAGCGGCTTCACCTTGATCTTCGGGCTGATGCGCAATGTCAATCTCGCGCATGGC
TCGCTCTATCTGTTCGGCGGCTATGTCGGCTACGGCATATCGGCCGCGACGGGCTCCTGGATCCTCGCCTTCATCGCGGC
CTTCGTTGTCGTCGCCGTGATCGGCGTGCTGCTTCAGCTGCTCGTGTTCCGCCGCATGGAGGGGCAGGATCTGCGGCAGA
CGATGGTCACGATCGGTCTGTCGATCGTGTTCGCCGACCTGATGCTGTGGGCGTTCGGCGGCGATTTCTATCAGATCCAG
ACGCCGGCCTGGCTGATCGGGCCGGTCCAGCTGCCGCTGATGACCGCAATGAAATCATCGGGCGAGGCGGTGTTCCTGCA
ATATCCGCTGGTGCGGCTCGTGATCTTCTGCGGCTCGGTCGTGATCGGCATCCTGATGTGGCTCGCATTGAACCGGACCC
GGGTCGGCATGATCGTGCGCGCCGGCGTCGACGATCGCGAAATCCTGGCCGCGACCGGCGTGCAGATCCAGCTCGTCTTC
GTCCTGGTGTTCGCCTTCGGCGCCGGATTGGCCGGGATCGCCGGCGTGGTCGGCGGCACGTTCCAGTCGATCTCGCCCGG
CGAGGATACGCGATTCCTTCTGGCCTCCCTTGTCGTCGTCATCGTCGGCGGCATGGGATCCATTCCCGGCGCCGCGCTCG
GCGCGCTCATCATCGGTCTCGCCGAGCAGCTCGGGTCGGTCTACATCCCGACCTACGCGATCGTCGTGACGTTCCTGATC
ATGGTCCTGGTCCTGGCGCTGCGGCCGCAGGGCCTGCTGGCGAGGCGGTGA

Upstream 100 bases:

>100_bases
ACAAGCCCGGGCATGACGCAGTGACTAAGTGGCGAAATTGGCCGTCGCGGCAGCGTCGTATTTCAGGATACCCTTGTGCT
GCGCTCGCGAGGGGTCGCCG

Downstream 100 bases:

>100_bases
GATGTCGCTGATCCAGGAGGCGCGGGCGAGGGAGGGCTTGCTGTCAGGCGGCGCGGCGGAGCGGCCCGCCACATGGTCCG
TGACCGAGCAGCCCTGGGCA

Product: putative ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSRFIERHPIWSLVILIAIACLAWLIIAVWPPGLEDAIGRKKVFLSAVFNGITLGGLYFLVASGFTLIFGLMRNVNLAHG
SLYLFGGYVGYGISAATGSWILAFIAAFVVVAVIGVLLQLLVFRRMEGQDLRQTMVTIGLSIVFADLMLWAFGGDFYQIQ
TPAWLIGPVQLPLMTAMKSSGEAVFLQYPLVRLVIFCGSVVIGILMWLALNRTRVGMIVRAGVDDREILAATGVQIQLVF
VLVFAFGAGLAGIAGVVGGTFQSISPGEDTRFLLASLVVVIVGGMGSIPGAALGALIIGLAEQLGSVYIPTYAIVVTFLI
MVLVLALRPQGLLARR

Sequences:

>Translated_336_residues
MSRFIERHPIWSLVILIAIACLAWLIIAVWPPGLEDAIGRKKVFLSAVFNGITLGGLYFLVASGFTLIFGLMRNVNLAHG
SLYLFGGYVGYGISAATGSWILAFIAAFVVVAVIGVLLQLLVFRRMEGQDLRQTMVTIGLSIVFADLMLWAFGGDFYQIQ
TPAWLIGPVQLPLMTAMKSSGEAVFLQYPLVRLVIFCGSVVIGILMWLALNRTRVGMIVRAGVDDREILAATGVQIQLVF
VLVFAFGAGLAGIAGVVGGTFQSISPGEDTRFLLASLVVVIVGGMGSIPGAALGALIIGLAEQLGSVYIPTYAIVVTFLI
MVLVLALRPQGLLARR
>Mature_335_residues
SRFIERHPIWSLVILIAIACLAWLIIAVWPPGLEDAIGRKKVFLSAVFNGITLGGLYFLVASGFTLIFGLMRNVNLAHGS
LYLFGGYVGYGISAATGSWILAFIAAFVVVAVIGVLLQLLVFRRMEGQDLRQTMVTIGLSIVFADLMLWAFGGDFYQIQT
PAWLIGPVQLPLMTAMKSSGEAVFLQYPLVRLVIFCGSVVIGILMWLALNRTRVGMIVRAGVDDREILAATGVQIQLVFV
LVFAFGAGLAGIAGVVGGTFQSISPGEDTRFLLASLVVVIVGGMGSIPGAALGALIIGLAEQLGSVYIPTYAIVVTFLIM
VLVLALRPQGLLARR

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=310, Percent_Identity=30.9677419354839, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35920; Mature: 35789

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFIERHPIWSLVILIAIACLAWLIIAVWPPGLEDAIGRKKVFLSAVFNGITLGGLYFL
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASGFTLIFGLMRNVNLAHGSLYLFGGYVGYGISAATGSWILAFIAAFVVVAVIGVLLQL
HHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFRRMEGQDLRQTMVTIGLSIVFADLMLWAFGGDFYQIQTPAWLIGPVQLPLMTAMKSS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHHHHHHHHHCC
GEAVFLQYPLVRLVIFCGSVVIGILMWLALNRTRVGMIVRAGVDDREILAATGVQIQLVF
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEECCCCCHHHHHHCCCHHHHHH
VLVFAFGAGLAGIAGVVGGTFQSISPGEDTRFLLASLVVVIVGGMGSIPGAALGALIIGL
HHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AEQLGSVYIPTYAIVVTFLIMVLVLALRPQGLLARR
HHHHCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SRFIERHPIWSLVILIAIACLAWLIIAVWPPGLEDAIGRKKVFLSAVFNGITLGGLYFL
CCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASGFTLIFGLMRNVNLAHGSLYLFGGYVGYGISAATGSWILAFIAAFVVVAVIGVLLQL
HHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFRRMEGQDLRQTMVTIGLSIVFADLMLWAFGGDFYQIQTPAWLIGPVQLPLMTAMKSS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHHHHHHHHHCC
GEAVFLQYPLVRLVIFCGSVVIGILMWLALNRTRVGMIVRAGVDDREILAATGVQIQLVF
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEECCCCCHHHHHHCCCHHHHHH
VLVFAFGAGLAGIAGVVGGTFQSISPGEDTRFLLASLVVVIVGGMGSIPGAALGALIIGL
HHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AEQLGSVYIPTYAIVVTFLIMVLVLALRPQGLLARR
HHHHCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]