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The map label for this gene is engA [H]

Identifier: 146340695

GI number: 146340695

Start: 3908761

End: 3910131

Strand: Direct

Name: engA [H]

Synonym: BRADO3746

Alternate gene names: 146340695

Gene position: 3908761-3910131 (Clockwise)

Preceding gene: 146340694

Following gene: 146340697

Centisome position: 52.42

GC content: 67.69

Gene sequence:

>1371_bases
ATGTCTTTTACCATCGCCATCATCGGCCGGCCCAATGTCGGCAAATCGACCCTGTTCAACCGTCTGGTGGGGCAGAAGCT
GGCGCTCGTCGACGACATGCCTGGCGTGACCCGCGACCGCCGCGAGGGCGAGGCGAAGCTGCACGACCTGCATTTCACGA
TCATCGACACCGCCGGCCTTGACGAGGGCCCGAAGGGCTCGCTGACGGCGCGGATGCAGGAGCAGACGGAGACCGCGATC
GCGCTCGCCGATGCCCTGTTCTTCGTCATCGATGCCCGCGTTGGCTTGACACCGGCCGACCGCGCCTTCGCCGATTTCGC
CCGCCGCGCCGACAAGCCGGTGCTGCTGCTCGCCAACAAGAGCGAAGGCAAGCATGGCGAACTCGGCGCGATGGAGTCCT
ACGCGCTCGGTCTCGGCGATCCGATTCAGATCTCGGCCGAGCATGGCGAGGGCATGGGCGAGCTCTACGATGCACTCAGC
AAGATCGTACCGCCCTCGGACGACGAGGATGACGAGCGCGAGGAGACCGACGAGGAGCGCGCCAGCCGGCCGATCCGCGT
CGCCATCGTCGGTCGTCCCAATGCCGGCAAGTCGACCCTGATCAACCACCTGCTCGGCGAGGAGCGCCTGCTGACCAGCC
CCGAGGCCGGCACCACCCGCGACTCGATCGCCGTCGAGGTCGAATGGAAGGGCCGCGGCTTCCGCATCTTCGATACCGCC
GGCCTGCGGCGGCGGTCGCGGATCGAGGAGAAGCTGGAGAAACTCTCGGTGGCGGATGCGCTGCGGGCGGTGCGGTTTGC
CGAGGTCGTGGTGCTGATGTTGGACGCGCAGAACCGCTTCGAGGAGCAGGATCTTCGCATCGCCGACCTGGTCGAGCGCG
AGGGGCGGGCGCTGGTGCTGGCGGTCAACAAATGGGACCTGATGGAGGCCCAGCCCGGACAGATCTCGGCGCTGCGCCGG
GATGCCGACCATTGGCTGCCGCAGATCACCGGCGCGCCGATCGTGGCAGTGTCCGGCCTGATGGGCGAGGGCATCGACCG
GCTGATGCAGGCGATCGTCGAGGCCTACGCGGTCTGGAATCGGCGCGTGCCGACGGCGGCGCTGAACCGCTGGTTCGAGG
GCGCGATCGCTAACAATCCGCCGCCTGCCGTGTCGGGCCGCCGCCTCAAGCTGAACTACATCACCCAGACCAAGGCGCGG
CCGCCGAGCTTCGTGCTGTTCTGCTCGCGCGCCGACGCGATCCCGCAATCCTATCTGCGCTACCTCGTCAACTCGATGCG
CGAGACCTTCGAGCTGCCGGGCACGCCGGTGCGCATCACCTTGCGCGAGAAGGCCAACCCATTCGCCCACAAGCGCAAGC
GGCCGAACTGA

Upstream 100 bases:

>100_bases
CTCCTTCAGCCGTTAATCTCATCGGCGAATCGGCCGATCGCCCGTTCGGTTTTACGGTCGGATGCGCTAAAGCTGCGCGC
CAACGCGCGCTCGGATCATC

Downstream 100 bases:

>100_bases
TCGGCTTGCTACAGGCCGCGCGTCTGGACTTTTGATCTGATCGCGACAAGCGTCCATTCCTCGCCTCAATCCGACGAAAA
CCCGAACGGTACCGACGATG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSFTIAIIGRPNVGKSTLFNRLVGQKLALVDDMPGVTRDRREGEAKLHDLHFTIIDTAGLDEGPKGSLTARMQEQTETAI
ALADALFFVIDARVGLTPADRAFADFARRADKPVLLLANKSEGKHGELGAMESYALGLGDPIQISAEHGEGMGELYDALS
KIVPPSDDEDDEREETDEERASRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEVEWKGRGFRIFDTA
GLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMLDAQNRFEEQDLRIADLVEREGRALVLAVNKWDLMEAQPGQISALRR
DADHWLPQITGAPIVAVSGLMGEGIDRLMQAIVEAYAVWNRRVPTAALNRWFEGAIANNPPPAVSGRRLKLNYITQTKAR
PPSFVLFCSRADAIPQSYLRYLVNSMRETFELPGTPVRITLREKANPFAHKRKRPN

Sequences:

>Translated_456_residues
MSFTIAIIGRPNVGKSTLFNRLVGQKLALVDDMPGVTRDRREGEAKLHDLHFTIIDTAGLDEGPKGSLTARMQEQTETAI
ALADALFFVIDARVGLTPADRAFADFARRADKPVLLLANKSEGKHGELGAMESYALGLGDPIQISAEHGEGMGELYDALS
KIVPPSDDEDDEREETDEERASRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEVEWKGRGFRIFDTA
GLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMLDAQNRFEEQDLRIADLVEREGRALVLAVNKWDLMEAQPGQISALRR
DADHWLPQITGAPIVAVSGLMGEGIDRLMQAIVEAYAVWNRRVPTAALNRWFEGAIANNPPPAVSGRRLKLNYITQTKAR
PPSFVLFCSRADAIPQSYLRYLVNSMRETFELPGTPVRITLREKANPFAHKRKRPN
>Mature_455_residues
SFTIAIIGRPNVGKSTLFNRLVGQKLALVDDMPGVTRDRREGEAKLHDLHFTIIDTAGLDEGPKGSLTARMQEQTETAIA
LADALFFVIDARVGLTPADRAFADFARRADKPVLLLANKSEGKHGELGAMESYALGLGDPIQISAEHGEGMGELYDALSK
IVPPSDDEDDEREETDEERASRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEVEWKGRGFRIFDTAG
LRRRSRIEEKLEKLSVADALRAVRFAEVVVLMLDAQNRFEEQDLRIADLVEREGRALVLAVNKWDLMEAQPGQISALRRD
ADHWLPQITGAPIVAVSGLMGEGIDRLMQAIVEAYAVWNRRVPTAALNRWFEGAIANNPPPAVSGRRLKLNYITQTKARP
PSFVLFCSRADAIPQSYLRYLVNSMRETFELPGTPVRITLREKANPFAHKRKRPN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=474, Percent_Identity=40.084388185654, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1788919, Length=190, Percent_Identity=30.5263157894737, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367268, Length=167, Percent_Identity=30.5389221556886, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=138, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50553; Mature: 50422

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTIAIIGRPNVGKSTLFNRLVGQKLALVDDMPGVTRDRREGEAKLHDLHFTIIDTAGL
CEEEEEEEECCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECCC
DEGPKGSLTARMQEQTETAIALADALFFVIDARVGLTPADRAFADFARRADKPVLLLANK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEC
SEGKHGELGAMESYALGLGDPIQISAEHGEGMGELYDALSKIVPPSDDEDDEREETDEER
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ASRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEVEWKGRGFRIFDTA
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECC
GLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMLDAQNRFEEQDLRIADLVEREGRALVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCHHHHHHHCCCCEEEE
AVNKWDLMEAQPGQISALRRDADHWLPQITGAPIVAVSGLMGEGIDRLMQAIVEAYAVWN
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
RRVPTAALNRWFEGAIANNPPPAVSGRRLKLNYITQTKARPPSFVLFCSRADAIPQSYLR
CCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHH
YLVNSMRETFELPGTPVRITLREKANPFAHKRKRPN
HHHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure 
SFTIAIIGRPNVGKSTLFNRLVGQKLALVDDMPGVTRDRREGEAKLHDLHFTIIDTAGL
EEEEEEEECCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECCC
DEGPKGSLTARMQEQTETAIALADALFFVIDARVGLTPADRAFADFARRADKPVLLLANK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEC
SEGKHGELGAMESYALGLGDPIQISAEHGEGMGELYDALSKIVPPSDDEDDEREETDEER
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ASRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEVEWKGRGFRIFDTA
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECC
GLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMLDAQNRFEEQDLRIADLVEREGRALVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCHHHHHHHCCCCEEEE
AVNKWDLMEAQPGQISALRRDADHWLPQITGAPIVAVSGLMGEGIDRLMQAIVEAYAVWN
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
RRVPTAALNRWFEGAIANNPPPAVSGRRLKLNYITQTKARPPSFVLFCSRADAIPQSYLR
CCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHH
YLVNSMRETFELPGTPVRITLREKANPFAHKRKRPN
HHHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA