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The map label for this gene is paaG [H]

Identifier: 146339501

GI number: 146339501

Start: 2658442

End: 2659197

Strand: Reverse

Name: paaG [H]

Synonym: BRADO2490

Alternate gene names: 146339501

Gene position: 2659197-2658442 (Counterclockwise)

Preceding gene: 146339503

Following gene: 146339498

Centisome position: 35.66

GC content: 68.52

Gene sequence:

>756_bases
CTGTCCATCGACGGACCGATTGCGACCATCACGCTGGATCGCCCGGCCGCGTTCAACGCCATCAACCTCGCCATCGCCAA
GCGGCTGGAACAGCTCGCGGCGCAGGTCGAAGCCGATCCGACCATCCGGGTGCTCGTCCTGAAGGGCGAGGGCCGCGCCT
TCTGCGCCGGCGGCGACCTGCAGACGATCGGCGCCGCGGCCGAGGCCGACACCATTACGACCGTGGTCAGCGAGCTCTTG
CATCACTACCACGCCTTCATCGCGAGCCTGCGGCGGATGCCAAAGATCGTGCTCGCGAGCGTGCATGGCTCCGCGGCCGG
TGCCGGGATGTCGCTCGCCTTCGCTGCCGACCTCTGCATCGCCGCCGAGGAAGCGCGCTTCACACCGGCCTACGCCAAGC
TCGGCGTTTCGCCTGACGGCGGCGGCACGGTGGGTGTCGTCGCCACCGCGGGTGTCCGGCGCGCGCTGCAGATCTTCCTC
GCGGAAGACAGCTTCACGGCCGCACAGGCCAGCGAATGGGGCCTGGTCGCCAAGGTCGTTGCCGCATCCGAGCTGGCTGC
GGCGACCGAGGCGTTGGCGCAGCGGCTGGCCCAGAACATGCCGGCGGGGATCGCTGCGACCAAGGCGCTGATCCATCGCG
CTCCCACCAGTTCGGTCGAGGACCAGCTCGGCGCCGAGCGCGATGCGATCATCAATTGCATGCACACCGACGGATTCCGT
GCCGCTGTGAAGCGGTTCACCAGCAAAGGAAAGTAG

Upstream 100 bases:

>100_bases
ACTTCCCCGGCATTGTCACCGGGCCGCTGTGCGCCTTAAATGCGGCAACAACGATACAAGGGAGGACTGAATGTCGGACG
CAGCCGCGGAACCCGCTCGC

Downstream 100 bases:

>100_bases
GACTGAGCTCACCCTTTTCCTTGTCCCTTCCCTTTCCGGCGCATGAAATCGAAATCGCAGCCGTCGTCGGCCTGCAGGAT
CGTTTCATGAAACAGATGCG

Product: putative enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSIDGPIATITLDRPAAFNAINLAIAKRLEQLAAQVEADPTIRVLVLKGEGRAFCAGGDLQTIGAAAEADTITTVVSELL
HHYHAFIASLRRMPKIVLASVHGSAAGAGMSLAFAADLCIAAEEARFTPAYAKLGVSPDGGGTVGVVATAGVRRALQIFL
AEDSFTAAQASEWGLVAKVVAASELAAATEALAQRLAQNMPAGIAATKALIHRAPTSSVEDQLGAERDAIINCMHTDGFR
AAVKRFTSKGK

Sequences:

>Translated_251_residues
MSIDGPIATITLDRPAAFNAINLAIAKRLEQLAAQVEADPTIRVLVLKGEGRAFCAGGDLQTIGAAAEADTITTVVSELL
HHYHAFIASLRRMPKIVLASVHGSAAGAGMSLAFAADLCIAAEEARFTPAYAKLGVSPDGGGTVGVVATAGVRRALQIFL
AEDSFTAAQASEWGLVAKVVAASELAAATEALAQRLAQNMPAGIAATKALIHRAPTSSVEDQLGAERDAIINCMHTDGFR
AAVKRFTSKGK
>Mature_250_residues
SIDGPIATITLDRPAAFNAINLAIAKRLEQLAAQVEADPTIRVLVLKGEGRAFCAGGDLQTIGAAAEADTITTVVSELLH
HYHAFIASLRRMPKIVLASVHGSAAGAGMSLAFAADLCIAAEEARFTPAYAKLGVSPDGGGTVGVVATAGVRRALQIFLA
EDSFTAAQASEWGLVAKVVAASELAAATEALAQRLAQNMPAGIAATKALIHRAPTSSVEDQLGAERDAIINCMHTDGFRA
AVKRFTSKGK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=27.4193548387097, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI157694516, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI213417737, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI37594469, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI37594471, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI70995211, Length=227, Percent_Identity=25.9911894273128, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI25453481, Length=208, Percent_Identity=25.4807692307692, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI51538573, Length=208, Percent_Identity=25.4807692307692, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4757966, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI51538581, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI31542718, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787660, Length=245, Percent_Identity=36.734693877551, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787659, Length=246, Percent_Identity=31.3008130081301, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI221142681, Length=222, Percent_Identity=32.4324324324324, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788597, Length=214, Percent_Identity=32.7102803738318, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790281, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=30.4526748971193, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=189, Percent_Identity=31.2169312169312, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=221, Percent_Identity=28.5067873303167, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=229, Percent_Identity=26.6375545851528, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=231, Percent_Identity=27.7056277056277, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=24, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=26.9767441860465, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129971, Length=221, Percent_Identity=28.0542986425339, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24653477, Length=221, Percent_Identity=28.0542986425339, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24654903, Length=183, Percent_Identity=26.2295081967213, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24650670, Length=178, Percent_Identity=32.5842696629214, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653139, Length=213, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19920382, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357171, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 25901; Mature: 25770

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDGPIATITLDRPAAFNAINLAIAKRLEQLAAQVEADPTIRVLVLKGEGRAFCAGGDL
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCH
QTIGAAAEADTITTVVSELLHHYHAFIASLRRMPKIVLASVHGSAAGAGMSLAFAADLCI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCHHHHHHHHHH
AAEEARFTPAYAKLGVSPDGGGTVGVVATAGVRRALQIFLAEDSFTAAQASEWGLVAKVV
HHHHCCCCHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
AASELAAATEALAQRLAQNMPAGIAATKALIHRAPTSSVEDQLGAERDAIINCMHTDGFR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHHEEECCCCHHH
AAVKRFTSKGK
HHHHHHHCCCC
>Mature Secondary Structure 
SIDGPIATITLDRPAAFNAINLAIAKRLEQLAAQVEADPTIRVLVLKGEGRAFCAGGDL
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCH
QTIGAAAEADTITTVVSELLHHYHAFIASLRRMPKIVLASVHGSAAGAGMSLAFAADLCI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCHHHHHHHHHH
AAEEARFTPAYAKLGVSPDGGGTVGVVATAGVRRALQIFLAEDSFTAAQASEWGLVAKVV
HHHHCCCCHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHH
AASELAAATEALAQRLAQNMPAGIAATKALIHRAPTSSVEDQLGAERDAIINCMHTDGFR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHHEEECCCCHHH
AAVKRFTSKGK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]