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The map label for this gene is rbsK [H]

Identifier: 146339503

GI number: 146339503

Start: 2660610

End: 2661518

Strand: Reverse

Name: rbsK [H]

Synonym: BRADO2492

Alternate gene names: 146339503

Gene position: 2661518-2660610 (Counterclockwise)

Preceding gene: 146339504

Following gene: 146339501

Centisome position: 35.69

GC content: 69.2

Gene sequence:

>909_bases
ATGGGGCGCGTCGTCGTTGCCGGCAGCATCAACATGGATGTCGTGGCGACGGCCGAGCGCCATCCTCGCGTCGGCGAGAC
CGTCGCGGGACAGTCGGTGATGTATTTTCCCGGCGGCAAGGGCGCCAATCAGGCGGTGGCGGCCGCCAAGCTCGGCGCGC
CGACGTCGCTGATCGGCCGGCTCGGCCGCGACGCGTTCGGCGAGCAGTTGCGGGCGTTTCTTGCCGCACAGGGCATCGAT
CTCGCGGCAGTGAAGGACAGCGCAGGCGTGTCGACGGGCACGGCGATCATCACGCTGGCGAAGGCCGACAACACCATCGT
GGTCATCCCTGGCGCCAATGCCGAGGTCCGCGCCGACGATGTGGGGCAGACCGCGCTGATTGCGGGTGACGTGGCGGTGA
GCCAGTTCGAGATCCCGCAAGCGACCATCGTGACGTTCTTCCAGCGGGCAAAAGCCGCCGGGGCCACGACGATCCTCAAT
CCCGCCCCGGCCAGCGCCTTCGCTCAGGGATTGTTCGCGGTGGTCGATGTCCTCGTGCTCAACGAGACCGAGCTCGGCTT
CCTGTCCGGCATCGACCTCGGCAACGCTCCCACGTCGCAGCAGGTCGTCGATGCTGTGTGGAAGCTCGATGCACGCACTG
ACCAGACGGTCTGCGTCACTCTGGGCGCGCGTGGCGCCGTAGCGGTGGCTGCCGGCGAGGCCAGACGGGTGGACGGCCGC
GCGGTGAAGGCCGTCGACACCACCGGCGCGGGCGATTGCTTCGTCGGTGCGCTGGCGGCACGGCTGTCGCAGGGCGCGGC
GATGACGGATGCGATCGCCTACGCCAATGTCGCCGCGTCGATCTCCGTGCAGCGGATGGGCGCCGGCCCATCGATGCCCA
CAGCAGAGGAGGTGCGCGCGCTGCTCTAG

Upstream 100 bases:

>100_bases
GAAGCTTGGCAACGAGGCCGGCCTGCCGACGCTCGCCGACATCGAGCTGGTGAGACAAGAGTTCGAAGCCCGCGTCTAGC
GGCTGTTTGGGAGAAGGCGG

Downstream 100 bases:

>100_bases
CCGAGCGCGCTCTTCAGGTCGAAGCTCGGATCGGCGGCCTCGGCCGGATCGATCGTGCCGCCCGCGGCGAGCAGCTTGCG
GCCGAACATGTGATCACCGG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MGRVVVAGSINMDVVATAERHPRVGETVAGQSVMYFPGGKGANQAVAAAKLGAPTSLIGRLGRDAFGEQLRAFLAAQGID
LAAVKDSAGVSTGTAIITLAKADNTIVVIPGANAEVRADDVGQTALIAGDVAVSQFEIPQATIVTFFQRAKAAGATTILN
PAPASAFAQGLFAVVDVLVLNETELGFLSGIDLGNAPTSQQVVDAVWKLDARTDQTVCVTLGARGAVAVAAGEARRVDGR
AVKAVDTTGAGDCFVGALAARLSQGAAMTDAIAYANVAASISVQRMGAGPSMPTAEEVRALL

Sequences:

>Translated_302_residues
MGRVVVAGSINMDVVATAERHPRVGETVAGQSVMYFPGGKGANQAVAAAKLGAPTSLIGRLGRDAFGEQLRAFLAAQGID
LAAVKDSAGVSTGTAIITLAKADNTIVVIPGANAEVRADDVGQTALIAGDVAVSQFEIPQATIVTFFQRAKAAGATTILN
PAPASAFAQGLFAVVDVLVLNETELGFLSGIDLGNAPTSQQVVDAVWKLDARTDQTVCVTLGARGAVAVAAGEARRVDGR
AVKAVDTTGAGDCFVGALAARLSQGAAMTDAIAYANVAASISVQRMGAGPSMPTAEEVRALL
>Mature_301_residues
GRVVVAGSINMDVVATAERHPRVGETVAGQSVMYFPGGKGANQAVAAAKLGAPTSLIGRLGRDAFGEQLRAFLAAQGIDL
AAVKDSAGVSTGTAIITLAKADNTIVVIPGANAEVRADDVGQTALIAGDVAVSQFEIPQATIVTFFQRAKAAGATTILNP
APASAFAQGLFAVVDVLVLNETELGFLSGIDLGNAPTSQQVVDAVWKLDARTDQTVCVTLGARGAVAVAAGEARRVDGRA
VKAVDTTGAGDCFVGALAARLSQGAAMTDAIAYANVAASISVQRMGAGPSMPTAEEVRALL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=299, Percent_Identity=36.1204013377926, Blast_Score=157, Evalue=8e-39,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=40.1315789473684, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082343, Length=309, Percent_Identity=27.1844660194175, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789775, Length=260, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=36.6336633663366, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=29.8507462686567, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=35.8306188925081, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24583886, Length=315, Percent_Identity=28.8888888888889, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30401; Mature: 30270

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVVVAGSINMDVVATAERHPRVGETVAGQSVMYFPGGKGANQAVAAAKLGAPTSLIGR
CCCEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCHHHHHH
LGRDAFGEQLRAFLAAQGIDLAAVKDSAGVSTGTAIITLAKADNTIVVIPGANAEVRADD
HCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEECC
VGQTALIAGDVAVSQFEIPQATIVTFFQRAKAAGATTILNPAPASAFAQGLFAVVDVLVL
CCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHC
NETELGFLSGIDLGNAPTSQQVVDAVWKLDARTDQTVCVTLGARGAVAVAAGEARRVDGR
CCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCEECCCC
AVKAVDTTGAGDCFVGALAARLSQGAAMTDAIAYANVAASISVQRMGAGPSMPTAEEVRA
EEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHH
LL
CC
>Mature Secondary Structure 
GRVVVAGSINMDVVATAERHPRVGETVAGQSVMYFPGGKGANQAVAAAKLGAPTSLIGR
CCEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCHHHHHH
LGRDAFGEQLRAFLAAQGIDLAAVKDSAGVSTGTAIITLAKADNTIVVIPGANAEVRADD
HCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEECC
VGQTALIAGDVAVSQFEIPQATIVTFFQRAKAAGATTILNPAPASAFAQGLFAVVDVLVL
CCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHC
NETELGFLSGIDLGNAPTSQQVVDAVWKLDARTDQTVCVTLGARGAVAVAAGEARRVDGR
CCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCEECCCC
AVKAVDTTGAGDCFVGALAARLSQGAAMTDAIAYANVAASISVQRMGAGPSMPTAEEVRA
EEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHH
LL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]