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The map label for this gene is mltB [H]

Identifier: 146338732

GI number: 146338732

Start: 1783291

End: 1784055

Strand: Direct

Name: mltB [H]

Synonym: BRADO1665

Alternate gene names: 146338732

Gene position: 1783291-1784055 (Clockwise)

Preceding gene: 146338730

Following gene: 146338734

Centisome position: 23.92

GC content: 69.67

Gene sequence:

>765_bases
TTGTTCGCGGCCTTCAGCGGAGCCCAGGCGGCGCAGTGCGGCACGTCGCCGGCCGGCTTCGAGGCGTGGAAGCGCGATTT
CAGCGAGGAGGCGCGCGCCAAGGGTATCGGAGGCACCGCGCTGTCGGCGCTGATGCAGACCAACTACGCGTCCGCGACGA
TCGCTGCCGATCGCGGCCAGCGCAGCTTCCAGCTGTCGCTCGATCAGTTCCTGGCCAAGCGCGGGGCGGCGGCAATCGTC
GCGCGCGGCCGCCAGCTCAAGCAGTCGCAGGCGGCGATGTTCGCCTCCATCGAGCAGCGCTACGGCGTGCCGCCGGGGCC
CTTGATCGCGATCTGGGGCATGGAGAGCGGCTTCGGCAGCCAGCGCGGCAATCAACACATGCTGTCGTCGATCGCGACGC
TTGCCTATGACTGCCGCCGTCCCGAATTCTTCACCGAGCAGCTCTATGCCGCGCTGAAGCTGATCGACCGCGGCGTGCTG
TCGGGCGCGACGCGCGGCTCGATGCATGGCGAGGTCGGGCAGACCCAGTTCATGCCCAAGAACATCCTGGCCTACGGCGT
CGGCAATCTCGACGTCGCCGCCAACGCGCTGGCCTCGACCGCCAACTTCCTCCGCGCCAATGGCTGGAAGGCCGGCGCCG
GCTACCAGCCCGGCGAACCGAACTTCGCCGCCATCGAAGCCTGGAACGCCGCCGGCGTCTACCAGAAGGCGATCGCCCTG
ATGGGCCGCCAGATCGACGGCGGCGGCTCGGCCGCGGAGCGGTGA

Upstream 100 bases:

>100_bases
TGTCACGCGGCTGTCATGCGGCACGCGTGACGACGCCACCAGAGGAGCATCAATGATCAAGCGCCGGGCCATCATCACGA
TCACCCTGACCGCCGCGACC

Downstream 100 bases:

>100_bases
GACGCGAAACCGATAGAACATCTGCAAACAAGAAAGCGGCGCTTCATCACTGAAGCGCCGCTTCTCGTTAGTCAGTCAGG
CTTCGGCATCACGCCTTCAG

Product: putative lytic murein transglycosylase

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFAAFSGAQAAQCGTSPAGFEAWKRDFSEEARAKGIGGTALSALMQTNYASATIAADRGQRSFQLSLDQFLAKRGAAAIV
ARGRQLKQSQAAMFASIEQRYGVPPGPLIAIWGMESGFGSQRGNQHMLSSIATLAYDCRRPEFFTEQLYAALKLIDRGVL
SGATRGSMHGEVGQTQFMPKNILAYGVGNLDVAANALASTANFLRANGWKAGAGYQPGEPNFAAIEAWNAAGVYQKAIAL
MGRQIDGGGSAAER

Sequences:

>Translated_254_residues
MFAAFSGAQAAQCGTSPAGFEAWKRDFSEEARAKGIGGTALSALMQTNYASATIAADRGQRSFQLSLDQFLAKRGAAAIV
ARGRQLKQSQAAMFASIEQRYGVPPGPLIAIWGMESGFGSQRGNQHMLSSIATLAYDCRRPEFFTEQLYAALKLIDRGVL
SGATRGSMHGEVGQTQFMPKNILAYGVGNLDVAANALASTANFLRANGWKAGAGYQPGEPNFAAIEAWNAAGVYQKAIAL
MGRQIDGGGSAAER
>Mature_254_residues
MFAAFSGAQAAQCGTSPAGFEAWKRDFSEEARAKGIGGTALSALMQTNYASATIAADRGQRSFQLSLDQFLAKRGAAAIV
ARGRQLKQSQAAMFASIEQRYGVPPGPLIAIWGMESGFGSQRGNQHMLSSIATLAYDCRRPEFFTEQLYAALKLIDRGVL
SGATRGSMHGEVGQTQFMPKNILAYGVGNLDVAANALASTANFLRANGWKAGAGYQPGEPNFAAIEAWNAAGVYQKAIAL
MGRQIDGGGSAAER

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=139, Percent_Identity=33.8129496402878, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 26798; Mature: 26798

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAAFSGAQAAQCGTSPAGFEAWKRDFSEEARAKGIGGTALSALMQTNYASATIAADRGQ
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCC
RSFQLSLDQFLAKRGAAAIVARGRQLKQSQAAMFASIEQRYGVPPGPLIAIWGMESGFGS
CCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
QRGNQHMLSSIATLAYDCRRPEFFTEQLYAALKLIDRGVLSGATRGSMHGEVGQTQFMPK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
NILAYGVGNLDVAANALASTANFLRANGWKAGAGYQPGEPNFAAIEAWNAAGVYQKAIAL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH
MGRQIDGGGSAAER
HCCCCCCCCCCCCC
>Mature Secondary Structure
MFAAFSGAQAAQCGTSPAGFEAWKRDFSEEARAKGIGGTALSALMQTNYASATIAADRGQ
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCC
RSFQLSLDQFLAKRGAAAIVARGRQLKQSQAAMFASIEQRYGVPPGPLIAIWGMESGFGS
CCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
QRGNQHMLSSIATLAYDCRRPEFFTEQLYAALKLIDRGVLSGATRGSMHGEVGQTQFMPK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
NILAYGVGNLDVAANALASTANFLRANGWKAGAGYQPGEPNFAAIEAWNAAGVYQKAIAL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH
MGRQIDGGGSAAER
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]