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The map label for this gene is acdA [H]

Identifier: 146338088

GI number: 146338088

Start: 1045381

End: 1046571

Strand: Direct

Name: acdA [H]

Synonym: BRADO0984

Alternate gene names: 146338088

Gene position: 1045381-1046571 (Clockwise)

Preceding gene: 146338087

Following gene: 146338089

Centisome position: 14.02

GC content: 63.31

Gene sequence:

>1191_bases
ATGGATCTTGCATTCACGAGGGAAGAGCAGGCGTTCCGCGAGGAAGTTCGGCAGTTCTTCAGGGACAACGTGCCGCCGGA
AACGCGCCGGAAAATGGTCGAGGGCCGGCATCTGTCGAAGGACGAGATGGTGACCTGGTGGCGCATCCTCAACAAGAAGG
GCTGGGGCGTCTCGCATTGGCCGAAGGAATATGGCGGCACCGGCTGGACCTCGGTGCAGCACTACATCTTCAATGAGGAG
CTGCAGGCCTATCCGGCGCCGCAGCCGCTCGCCTTCGGCGTCAGCATGGTCGGCCCGGTCATCTACACCTTCGGCAATGA
GGAGCAGAAGAAGAAGTACCTGCCGCGCATCGCCAATGTCGACGATTGGTGGTGCCAGGGCTTCTCCGAGCCGGGCTCGG
GCTCCGACCTCGCCTCGCTGAAGACCAAGGCCGAGCGCCGCGGCGACAAGTGGATCATCAACGGCCAGAAGACCTGGACG
ACGCTCGCCCAGCACGCCGACATGATCTTCTGCCTGTGCCGCACCGATCCCTCCGCCAAGAAGCAGATGGGCATCTCCTT
CATCGTCTTCAGCATGAAGTCGAAGGGCGTCACGGTGCGTCCTATCCAGACCATCGACGGCGGCCACGAGGTCAACGAGG
TGTTCTTCGACGACGTCGAGGTGCCGATCGAGAACCTGATCGGCGAGGAGAACAAGGGCTGGGACTACGCAAAATTCCTG
CTCGGCAATGAGCGCACCGGCATCGCCCGGGTCGGCGTCTCCAAGGAGCGCATCCGCCGCATCAAGGAGCTCGCCGCCAA
GGTCGAATCCGGCGGCCGTCCCGTGCTGGAGGATCCGTCGTTCCGCGAGAAGCTGACGGCCTGCGAGGTCGAGCTGAAGG
CGCTGGAGCTGACGCAGCTGCGCGTCGTCGCCGACGAGGGCAAGCACGGCAAGGGTAAGCCCAATCCCGCGTCCTCGGTG
CTGAAGATCAAGGGCTCCGAGATCCAGCAGACCACGACCGAGCTGCTGATGGAAGTGATCGGCCCGTTCGCCGCGCCCTA
CGACATCCATGGCGACGACGACAGCAACGAGACCATGGATTGGACCGCCCAGATCGCGCCGAGCTACTTCAACAACCGCA
AGGTCTCGATCTACGGCGGCTCCAACGAGATTCAGCGCAACATCATCGCCAAGGCGGTGCTGGGGCTGTAG

Upstream 100 bases:

>100_bases
CGTCCCAACGTCCGCCGGTGGTTATGGGTCCCGGCTTTCGCCGGGACGACGTCGGAGCGAGACGAACTAACAGGACCATA
CGACACACGGGAGCGATCCA

Downstream 100 bases:

>100_bases
CAACATACACAGGTGTCGTCCCCCGCGCAGGCGGGGGACCCAGTACGCCGCGGCGGTCGTGATGAAGCACTGGCGCCGGT
GATTACTGGATCCCCGCTTT

Product: putative acyl-CoA dehydrogenase/pimeloyl-CoA dehydrogenase pimC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MDLAFTREEQAFREEVRQFFRDNVPPETRRKMVEGRHLSKDEMVTWWRILNKKGWGVSHWPKEYGGTGWTSVQHYIFNEE
LQAYPAPQPLAFGVSMVGPVIYTFGNEEQKKKYLPRIANVDDWWCQGFSEPGSGSDLASLKTKAERRGDKWIINGQKTWT
TLAQHADMIFCLCRTDPSAKKQMGISFIVFSMKSKGVTVRPIQTIDGGHEVNEVFFDDVEVPIENLIGEENKGWDYAKFL
LGNERTGIARVGVSKERIRRIKELAAKVESGGRPVLEDPSFREKLTACEVELKALELTQLRVVADEGKHGKGKPNPASSV
LKIKGSEIQQTTTELLMEVIGPFAAPYDIHGDDDSNETMDWTAQIAPSYFNNRKVSIYGGSNEIQRNIIAKAVLGL

Sequences:

>Translated_396_residues
MDLAFTREEQAFREEVRQFFRDNVPPETRRKMVEGRHLSKDEMVTWWRILNKKGWGVSHWPKEYGGTGWTSVQHYIFNEE
LQAYPAPQPLAFGVSMVGPVIYTFGNEEQKKKYLPRIANVDDWWCQGFSEPGSGSDLASLKTKAERRGDKWIINGQKTWT
TLAQHADMIFCLCRTDPSAKKQMGISFIVFSMKSKGVTVRPIQTIDGGHEVNEVFFDDVEVPIENLIGEENKGWDYAKFL
LGNERTGIARVGVSKERIRRIKELAAKVESGGRPVLEDPSFREKLTACEVELKALELTQLRVVADEGKHGKGKPNPASSV
LKIKGSEIQQTTTELLMEVIGPFAAPYDIHGDDDSNETMDWTAQIAPSYFNNRKVSIYGGSNEIQRNIIAKAVLGL
>Mature_396_residues
MDLAFTREEQAFREEVRQFFRDNVPPETRRKMVEGRHLSKDEMVTWWRILNKKGWGVSHWPKEYGGTGWTSVQHYIFNEE
LQAYPAPQPLAFGVSMVGPVIYTFGNEEQKKKYLPRIANVDDWWCQGFSEPGSGSDLASLKTKAERRGDKWIINGQKTWT
TLAQHADMIFCLCRTDPSAKKQMGISFIVFSMKSKGVTVRPIQTIDGGHEVNEVFFDDVEVPIENLIGEENKGWDYAKFL
LGNERTGIARVGVSKERIRRIKELAAKVESGGRPVLEDPSFREKLTACEVELKALELTQLRVVADEGKHGKGKPNPASSV
LKIKGSEIQQTTTELLMEVIGPFAAPYDIHGDDDSNETMDWTAQIAPSYFNNRKVSIYGGSNEIQRNIIAKAVLGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=400, Percent_Identity=27, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI4557231, Length=403, Percent_Identity=26.5508684863524, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI187960098, Length=403, Percent_Identity=26.5508684863524, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4501859, Length=405, Percent_Identity=27.1604938271605, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226958412, Length=234, Percent_Identity=27.7777777777778, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4557233, Length=341, Percent_Identity=26.099706744868, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958414, Length=201, Percent_Identity=30.8457711442786, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7656849, Length=347, Percent_Identity=25.6484149855908, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI76496475, Length=347, Percent_Identity=28.8184438040346, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557235, Length=347, Percent_Identity=28.8184438040346, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4503943, Length=314, Percent_Identity=27.3885350318471, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI7669494, Length=258, Percent_Identity=29.0697674418605, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI21361497, Length=271, Percent_Identity=29.8892988929889, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI48976061, Length=255, Percent_Identity=24.3137254901961, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI211971008, Length=255, Percent_Identity=24.3137254901961, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=330, Percent_Identity=26.3636363636364, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786223, Length=344, Percent_Identity=23.8372093023256, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=421, Percent_Identity=26.8408551068884, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=262, Percent_Identity=29.3893129770992, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=345, Percent_Identity=28.1159420289855, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=399, Percent_Identity=27.0676691729323, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17534899, Length=361, Percent_Identity=26.8698060941828, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=398, Percent_Identity=26.1306532663317, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=194, Percent_Identity=35.5670103092784, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=254, Percent_Identity=32.6771653543307, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=254, Percent_Identity=32.6771653543307, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=252, Percent_Identity=28.1746031746032, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=257, Percent_Identity=28.0155642023346, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=212, Percent_Identity=26.8867924528302, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534353, Length=260, Percent_Identity=27.3076923076923, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=203, Percent_Identity=25.615763546798, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=248, Percent_Identity=27.8225806451613, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356377, Length=398, Percent_Identity=25.3768844221106, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355753, Length=234, Percent_Identity=31.1965811965812, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24660351, Length=404, Percent_Identity=26.2376237623762, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281363737, Length=252, Percent_Identity=29.3650793650794, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24666513, Length=300, Percent_Identity=26, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646207, Length=401, Percent_Identity=23.9401496259352, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920834, Length=405, Percent_Identity=24.1975308641975, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44759; Mature: 44759

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAFTREEQAFREEVRQFFRDNVPPETRRKMVEGRHLSKDEMVTWWRILNKKGWGVSHW
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
PKEYGGTGWTSVQHYIFNEELQAYPAPQPLAFGVSMVGPVIYTFGNEEQKKKYLPRIANV
CHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCHHHHHHHCCCCCCC
DDWWCQGFSEPGSGSDLASLKTKAERRGDKWIINGQKTWTTLAQHADMIFCLCRTDPSAK
CHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCEEEEEECCCCCHH
KQMGISFIVFSMKSKGVTVRPIQTIDGGHEVNEVFFDDVEVPIENLIGEENKGWDYAKFL
HHCCCEEEEEEECCCCEEEEEEHCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHH
LGNERTGIARVGVSKERIRRIKELAAKVESGGRPVLEDPSFREKLTACEVELKALELTQL
HCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEE
RVVADEGKHGKGKPNPASSVLKIKGSEIQQTTTELLMEVIGPFAAPYDIHGDDDSNETMD
EEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
WTAQIAPSYFNNRKVSIYGGSNEIQRNIIAKAVLGL
HHEEECHHHHCCCEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLAFTREEQAFREEVRQFFRDNVPPETRRKMVEGRHLSKDEMVTWWRILNKKGWGVSHW
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
PKEYGGTGWTSVQHYIFNEELQAYPAPQPLAFGVSMVGPVIYTFGNEEQKKKYLPRIANV
CHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCHHHHHHHCCCCCCC
DDWWCQGFSEPGSGSDLASLKTKAERRGDKWIINGQKTWTTLAQHADMIFCLCRTDPSAK
CHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCEEEEEECCCCCHH
KQMGISFIVFSMKSKGVTVRPIQTIDGGHEVNEVFFDDVEVPIENLIGEENKGWDYAKFL
HHCCCEEEEEEECCCCEEEEEEHCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHH
LGNERTGIARVGVSKERIRRIKELAAKVESGGRPVLEDPSFREKLTACEVELKALELTQL
HCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEE
RVVADEGKHGKGKPNPASSVLKIKGSEIQQTTTELLMEVIGPFAAPYDIHGDDDSNETMD
EEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
WTAQIAPSYFNNRKVSIYGGSNEIQRNIIAKAVLGL
HHEEECHHHHCCCEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]