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The map label for this gene is lnt [H]

Identifier: 146337219

GI number: 146337219

Start: 50746

End: 52356

Strand: Direct

Name: lnt [H]

Synonym: BRADO0045

Alternate gene names: 146337219

Gene position: 50746-52356 (Clockwise)

Preceding gene: 146337218

Following gene: 146337220

Centisome position: 0.68

GC content: 63.81

Gene sequence:

>1611_bases
GTGATCCGCTTATCGATGATCCGCGGCCTCGTGCTTGGAATTGTCCTGGCCTGGGGCTGGAAGCGCGCGGCCATTGCGCT
CGCGGCAGGCGCCGTCTCCTCGCTAGCGATGGCCCCGTTCAATGCCTGGCCGGTACTGGCCGTCACCTTCCCTGTGCTGG
TCTGGCTGATCGATGGCGCGGCGGCGGGACGGCGGCGCGGCATTCCGGCGGCCGCCTTGACCGGCTTCTGCTTTGGCATG
GGCTATTTCGTCCCGGGGCTGTACTGGATCGGTAACGCCTTTCTGGTCGACGCCGATACGTTCGCCTGGCTGATGCCGTT
CGCAGTTCTTGGGCTCCCGGCCTATCTCGCGCTGTTCCCAGCACTGGGCTTTGCGCTCGCTCGGTTGTTGTGGACACGTG
ATGCAACCCGTATCCTGGCGCTGGCTGTCTGCCTGACCGCCAGCGAATGGCTGCGCGGCCACGCCCTGACCGGCTTCCCC
TGGAACACGTTCGGCTATGCGCTATCCCAGCCGCTCGCGCTGGCGCAAGCAGCGTCGCTGGTCGGCATCTGGGGCATGAC
GTTTGTCACGATCGCGGTTTTTGCCAGCCCCGCGGTGCTGATCGATGGCAAGACCTGGCGGGAGGGCTGGCGCGCGCCGG
CGGCAGCCGCTGCCGGGCTGGTTCTCTTGGGCGTGTTCGGCGCCGTCAGGCTCGGTCAGCATCCCACCGCCTTCGTCCCC
GATCTCAAGCTGCGGATCATGCAGCCGAATTTGCAGCAGGACGTCAAATTTAACTACGGCGCCAAGGCCGATGTGATGCG
GCGCTACCTCGCCCTCTCCGACCGCGCGTCGGGTCCGAAGTCGACAGGCGTGCGCGACACCGACGTCCTGATCTGGCCTG
AATCCGCATTCCCGTTCTTCCTGACCCGCGAAGCCGACGCGATGGGCCAGATCGCTGACCTGCTGCCGGCCGGAACGGTG
CTGATCACCGGTTCGGTCCGCGCGCCGGACGGCCCGCGCACTGGCCCCATCACGCGCGCCTATAACTCGATCTATGTGAT
CGATCACGACGGCACCGTGCTGTCGGTCTACGACAAGCTCCATCTGGTCCCGTTTGGCGAGTTTCTCCCGTTCCAGAATC
TGCTCGAGCGGATCGGGCTGGAGCAGCTGACCCGGGTGCAAGGCGGCTTCATCCCTGGTACGATCCGGCGCAACCTGGAC
GTGCCACACGCGCCGCGTGTATTGCCGCTAATCTGCTACGAAGCCATATTTCCGACTGATAGTGCAGCTAATGACGACCG
ACCGGGCTGGATCGTCAACCTGACCAATGACGGCTGGTTTGGTGTTTCGACCGGTCCTCATCAGCATCTGCAACAGGCGC
AATGGCGCGCCATCGAGCAGGGGCTTCCATTAGTTCGATCAGCGAACACGGGCATCTCTGCCGTGATCGATCCTGTCGGC
CGCATTATTTCGCAACTATCTCTGGGCACTGAGGGTGTGCTCGACGCTATGCTGCCTGTTGCCCTGCAGCCCACGATCTA
TGCGAGATTCGGCGATATTCCGGCTGCCATCCTGTTAGTGCTCGCCCTGAGCACAGTCGTTCGCAGACGTGTTGCTCAAA
AGCTTCCCTGA

Upstream 100 bases:

>100_bases
AGAGCGGCACCGCAGCCGAGCCGCCGCGACCGGTGGAGACCGGCCCCGCGTCCGGTCATGACGACAGCAGCCCGCCCCAA
GGCGACGGAGCAAGCTCACA

Downstream 100 bases:

>100_bases
CGACAGCAAGATTCTGTTTCTTTCCGGGTGCGTAAGATTTTTTTTGACAAGCAAAACCCCAAGTGTTGACAGATAGCTGC
TGCAATTCGCATTCTCGCGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MIRLSMIRGLVLGIVLAWGWKRAAIALAAGAVSSLAMAPFNAWPVLAVTFPVLVWLIDGAAAGRRRGIPAAALTGFCFGM
GYFVPGLYWIGNAFLVDADTFAWLMPFAVLGLPAYLALFPALGFALARLLWTRDATRILALAVCLTASEWLRGHALTGFP
WNTFGYALSQPLALAQAASLVGIWGMTFVTIAVFASPAVLIDGKTWREGWRAPAAAAAGLVLLGVFGAVRLGQHPTAFVP
DLKLRIMQPNLQQDVKFNYGAKADVMRRYLALSDRASGPKSTGVRDTDVLIWPESAFPFFLTREADAMGQIADLLPAGTV
LITGSVRAPDGPRTGPITRAYNSIYVIDHDGTVLSVYDKLHLVPFGEFLPFQNLLERIGLEQLTRVQGGFIPGTIRRNLD
VPHAPRVLPLICYEAIFPTDSAANDDRPGWIVNLTNDGWFGVSTGPHQHLQQAQWRAIEQGLPLVRSANTGISAVIDPVG
RIISQLSLGTEGVLDAMLPVALQPTIYARFGDIPAAILLVLALSTVVRRRVAQKLP

Sequences:

>Translated_536_residues
MIRLSMIRGLVLGIVLAWGWKRAAIALAAGAVSSLAMAPFNAWPVLAVTFPVLVWLIDGAAAGRRRGIPAAALTGFCFGM
GYFVPGLYWIGNAFLVDADTFAWLMPFAVLGLPAYLALFPALGFALARLLWTRDATRILALAVCLTASEWLRGHALTGFP
WNTFGYALSQPLALAQAASLVGIWGMTFVTIAVFASPAVLIDGKTWREGWRAPAAAAAGLVLLGVFGAVRLGQHPTAFVP
DLKLRIMQPNLQQDVKFNYGAKADVMRRYLALSDRASGPKSTGVRDTDVLIWPESAFPFFLTREADAMGQIADLLPAGTV
LITGSVRAPDGPRTGPITRAYNSIYVIDHDGTVLSVYDKLHLVPFGEFLPFQNLLERIGLEQLTRVQGGFIPGTIRRNLD
VPHAPRVLPLICYEAIFPTDSAANDDRPGWIVNLTNDGWFGVSTGPHQHLQQAQWRAIEQGLPLVRSANTGISAVIDPVG
RIISQLSLGTEGVLDAMLPVALQPTIYARFGDIPAAILLVLALSTVVRRRVAQKLP
>Mature_536_residues
MIRLSMIRGLVLGIVLAWGWKRAAIALAAGAVSSLAMAPFNAWPVLAVTFPVLVWLIDGAAAGRRRGIPAAALTGFCFGM
GYFVPGLYWIGNAFLVDADTFAWLMPFAVLGLPAYLALFPALGFALARLLWTRDATRILALAVCLTASEWLRGHALTGFP
WNTFGYALSQPLALAQAASLVGIWGMTFVTIAVFASPAVLIDGKTWREGWRAPAAAAAGLVLLGVFGAVRLGQHPTAFVP
DLKLRIMQPNLQQDVKFNYGAKADVMRRYLALSDRASGPKSTGVRDTDVLIWPESAFPFFLTREADAMGQIADLLPAGTV
LITGSVRAPDGPRTGPITRAYNSIYVIDHDGTVLSVYDKLHLVPFGEFLPFQNLLERIGLEQLTRVQGGFIPGTIRRNLD
VPHAPRVLPLICYEAIFPTDSAANDDRPGWIVNLTNDGWFGVSTGPHQHLQQAQWRAIEQGLPLVRSANTGISAVIDPVG
RIISQLSLGTEGVLDAMLPVALQPTIYARFGDIPAAILLVLALSTVVRRRVAQKLP

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=526, Percent_Identity=30.2281368821293, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57827; Mature: 57827

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLSMIRGLVLGIVLAWGWKRAAIALAAGAVSSLAMAPFNAWPVLAVTFPVLVWLIDGA
CEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
AAGRRRGIPAAALTGFCFGMGYFVPGLYWIGNAFLVDADTFAWLMPFAVLGLPAYLALFP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
ALGFALARLLWTRDATRILALAVCLTASEWLRGHALTGFPWNTFGYALSQPLALAQAASL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHH
VGIWGMTFVTIAVFASPAVLIDGKTWREGWRAPAAAAAGLVLLGVFGAVRLGQHPTAFVP
HHHHHHHHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DLKLRIMQPNLQQDVKFNYGAKADVMRRYLALSDRASGPKSTGVRDTDVLIWPESAFPFF
CCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEE
LTREADAMGQIADLLPAGTVLITGSVRAPDGPRTGPITRAYNSIYVIDHDGTVLSVYDKL
EECCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCE
HLVPFGEFLPFQNLLERIGLEQLTRVQGGFIPGTIRRNLDVPHAPRVLPLICYEAIFPTD
EECCCHHHCCHHHHHHHHCHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCC
SAANDDRPGWIVNLTNDGWFGVSTGPHQHLQQAQWRAIEQGLPLVRSANTGISAVIDPVG
CCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
RIISQLSLGTEGVLDAMLPVALQPTIYARFGDIPAAILLVLALSTVVRRRVAQKLP
HHHHHHHCCHHHHHHHHHHHHCCCHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRLSMIRGLVLGIVLAWGWKRAAIALAAGAVSSLAMAPFNAWPVLAVTFPVLVWLIDGA
CEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
AAGRRRGIPAAALTGFCFGMGYFVPGLYWIGNAFLVDADTFAWLMPFAVLGLPAYLALFP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
ALGFALARLLWTRDATRILALAVCLTASEWLRGHALTGFPWNTFGYALSQPLALAQAASL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHH
VGIWGMTFVTIAVFASPAVLIDGKTWREGWRAPAAAAAGLVLLGVFGAVRLGQHPTAFVP
HHHHHHHHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DLKLRIMQPNLQQDVKFNYGAKADVMRRYLALSDRASGPKSTGVRDTDVLIWPESAFPFF
CCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEE
LTREADAMGQIADLLPAGTVLITGSVRAPDGPRTGPITRAYNSIYVIDHDGTVLSVYDKL
EECCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCE
HLVPFGEFLPFQNLLERIGLEQLTRVQGGFIPGTIRRNLDVPHAPRVLPLICYEAIFPTD
EECCCHHHCCHHHHHHHHCHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCC
SAANDDRPGWIVNLTNDGWFGVSTGPHQHLQQAQWRAIEQGLPLVRSANTGISAVIDPVG
CCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
RIISQLSLGTEGVLDAMLPVALQPTIYARFGDIPAAILLVLALSTVVRRRVAQKLP
HHHHHHHCCHHHHHHHHHHHHCCCHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]