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The map label for this gene is tlyC [H]

Identifier: 146337218

GI number: 146337218

Start: 49550

End: 50749

Strand: Direct

Name: tlyC [H]

Synonym: BRADO0044

Alternate gene names: 146337218

Gene position: 49550-50749 (Clockwise)

Preceding gene: 146337217

Following gene: 146337219

Centisome position: 0.66

GC content: 68.25

Gene sequence:

>1200_bases
TTGACCATGGCCGACTCCGAGCCCATCCATGACAACCCGCGCCAGACGCGCAATCTGCCGGCCGTGGTGCCGCCGTCCGA
GCTCGGCCGTTCGCCGAGCGAGAACTGGCTGCTTCGTGCGTTGCGCAACCTGTTCGGCTGGAAGGGCGGCGGATCGGTGC
GCGACGATCTGCAGGTCGTGCTCGATGCCTCGACGCCCGACGACATCGGCTTCTCGGCGGTCGAGCGCACGCTCTTGCGC
AACATCCTCGACCTGCACGAGCGGCGGATCGCCGACGTCATGGTGCATCGGGCCGACATCGTTGCCGTGCGGCGTGACAT
CACGCTGGGCGAGCTGATGAGTCTGTTCGAAAGCGCGTCGCATTCACGCCTGGTGGTCTACAACGACACGCTCGACGACC
CCGAGGGCATGGTTCATATCCGCGACCTGCTCGCCTACATGACGGCGCAGGCGCGCGTCTCCGATGATGCGAAGGCCCGG
CGCAAGAAGCCGCTGCCTGCCGGGCTCGACCTGAAGAGCGTCGAGCTGTCGATGCCGCTGTTCGAGGCCAACATCATCCG
TAAATTGCTCTACGTGCCGCCCTCCATGCGCGCGATCGACCTGCTGGCGCAGATGCAGGCCTCGCGCATTCACCTCGCGC
TCGTGGTCGACGAATATGGCGGCACCGACGGGCTGGTCTCGATCGAGGACATCGTCGAGCAGATCGTCGGCGAGATCGAC
GATGAGCATGACAGCGACGAGCCGCCCGCGATCATGCGGCAGGCCGACAACGCATTCATCGCGGATGCGCGCGCGAGCCT
CGAGGATGTCCGCCGGGTGATCGGCGAGGAGTTCGTCACGGGCGAGGCCGGCGAAGGCGTCGAAACCCTGGGCGGCTATC
TCGTCAACCATGTCGGCCGGCTGCCGGTGCGCGGCGAGCTGATCTCGGGCCCCGGCAATTTCGAGGTCGAGGTGCTCGAC
GCCGACCCGCGCCGGGTCAAGCGGCTCCGTATCGCTCCGCGCAAGGAGCGGCCGACGCCGCGGCCGCCGCGCGAAAGCCG
GCGCCGCGAGGCCGCACCCGAAACGGCGCCCGAGACGACACCAGAGACAACATCCGAGAGCGGCACCGCAGCCGAGCCGC
CGCGACCGGTGGAGACCGGCCCCGCGTCCGGTCATGACGACAGCAGCCCGCCCCAAGGCGACGGAGCAAGCTCACAGTGA

Upstream 100 bases:

>100_bases
ACGAGACCGATGACGAGGCCGAGGAGATGGAGGCGCTAGAGACCGAAATCCTGGCCCATCTCGGCATCCCCGATCCCTAT
GCCGACCGGGAACGGATGCA

Downstream 100 bases:

>100_bases
TCCGCTTATCGATGATCCGCGGCCTCGTGCTTGGAATTGTCCTGGCCTGGGGCTGGAAGCGCGCGGCCATTGCGCTCGCG
GCAGGCGCCGTCTCCTCGCT

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTMADSEPIHDNPRQTRNLPAVVPPSELGRSPSENWLLRALRNLFGWKGGGSVRDDLQVVLDASTPDDIGFSAVERTLLR
NILDLHERRIADVMVHRADIVAVRRDITLGELMSLFESASHSRLVVYNDTLDDPEGMVHIRDLLAYMTAQARVSDDAKAR
RKKPLPAGLDLKSVELSMPLFEANIIRKLLYVPPSMRAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQIVGEID
DEHDSDEPPAIMRQADNAFIADARASLEDVRRVIGEEFVTGEAGEGVETLGGYLVNHVGRLPVRGELISGPGNFEVEVLD
ADPRRVKRLRIAPRKERPTPRPPRESRRREAAPETAPETTPETTSESGTAAEPPRPVETGPASGHDDSSPPQGDGASSQ

Sequences:

>Translated_399_residues
MTMADSEPIHDNPRQTRNLPAVVPPSELGRSPSENWLLRALRNLFGWKGGGSVRDDLQVVLDASTPDDIGFSAVERTLLR
NILDLHERRIADVMVHRADIVAVRRDITLGELMSLFESASHSRLVVYNDTLDDPEGMVHIRDLLAYMTAQARVSDDAKAR
RKKPLPAGLDLKSVELSMPLFEANIIRKLLYVPPSMRAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQIVGEID
DEHDSDEPPAIMRQADNAFIADARASLEDVRRVIGEEFVTGEAGEGVETLGGYLVNHVGRLPVRGELISGPGNFEVEVLD
ADPRRVKRLRIAPRKERPTPRPPRESRRREAAPETAPETTPETTSESGTAAEPPRPVETGPASGHDDSSPPQGDGASSQ
>Mature_398_residues
TMADSEPIHDNPRQTRNLPAVVPPSELGRSPSENWLLRALRNLFGWKGGGSVRDDLQVVLDASTPDDIGFSAVERTLLRN
ILDLHERRIADVMVHRADIVAVRRDITLGELMSLFESASHSRLVVYNDTLDDPEGMVHIRDLLAYMTAQARVSDDAKARR
KKPLPAGLDLKSVELSMPLFEANIIRKLLYVPPSMRAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQIVGEIDD
EHDSDEPPAIMRQADNAFIADARASLEDVRRVIGEEFVTGEAGEGVETLGGYLVNHVGRLPVRGELISGPGNFEVEVLDA
DPRRVKRLRIAPRKERPTPRPPRESRRREAAPETAPETTPETTSESGTAAEPPRPVETGPASGHDDSSPPQGDGASSQ

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=230, Percent_Identity=27.8260869565217, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1786879, Length=311, Percent_Identity=30.2250803858521, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082033, Length=274, Percent_Identity=27.3722627737226, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693175, Length=320, Percent_Identity=22.8125, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790664, Length=282, Percent_Identity=21.6312056737589, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 43755; Mature: 43624

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMADSEPIHDNPRQTRNLPAVVPPSELGRSPSENWLLRALRNLFGWKGGGSVRDDLQVV
CCCCCCCCCCCCCHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEE
LDASTPDDIGFSAVERTLLRNILDLHERRIADVMVHRADIVAVRRDITLGELMSLFESAS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
HSRLVVYNDTLDDPEGMVHIRDLLAYMTAQARVSDDAKARRKKPLPAGLDLKSVELSMPL
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCEEECCCH
FEANIIRKLLYVPPSMRAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQIVGEID
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHCC
DEHDSDEPPAIMRQADNAFIADARASLEDVRRVIGEEFVTGEAGEGVETLGGYLVNHVGR
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
LPVRGELISGPGNFEVEVLDADPRRVKRLRIAPRKERPTPRPPRESRRREAAPETAPETT
CCCCCEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
PETTSESGTAAEPPRPVETGPASGHDDSSPPQGDGASSQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMADSEPIHDNPRQTRNLPAVVPPSELGRSPSENWLLRALRNLFGWKGGGSVRDDLQVV
CCCCCCCCCCCCHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEE
LDASTPDDIGFSAVERTLLRNILDLHERRIADVMVHRADIVAVRRDITLGELMSLFESAS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
HSRLVVYNDTLDDPEGMVHIRDLLAYMTAQARVSDDAKARRKKPLPAGLDLKSVELSMPL
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCEEECCCH
FEANIIRKLLYVPPSMRAIDLLAQMQASRIHLALVVDEYGGTDGLVSIEDIVEQIVGEID
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHCC
DEHDSDEPPAIMRQADNAFIADARASLEDVRRVIGEEFVTGEAGEGVETLGGYLVNHVGR
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
LPVRGELISGPGNFEVEVLDADPRRVKRLRIAPRKERPTPRPPRESRRREAAPETAPETT
CCCCCEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
PETTSESGTAAEPPRPVETGPASGHDDSSPPQGDGASSQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA