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The map label for this gene is trpF [H]

Identifier: 146302622

GI number: 146302622

Start: 5916871

End: 5917503

Strand: Direct

Name: trpF [H]

Synonym: Fjoh_4895

Alternate gene names: 146302622

Gene position: 5916871-5917503 (Clockwise)

Preceding gene: 146302621

Following gene: 146302623

Centisome position: 97.05

GC content: 31.6

Gene sequence:

>633_bases
ATGAAACTCAAAATATGCGGTATGAAATATCCTGAAAACATTCTCGAAGTAGGTGCACTCCTGCCCGATTATATGGGATT
TATTTTCTGGGAAAAATCCGCGCGATATTTTAATGGAACTATTCCCGAACTTATAAAAACAATCAAAAAAGTGGGTGTTT
TTGTAAACCAAAGTCTGGAAGAAATTTTAGAAAAAGTCGTAAAACACAATTTACAAGCCGTTCAGTTACACGGAAATGAA
TCGGTTGAATTTGTATCGGAACTAAAAAAACAATTATCAAAAAAAATCGAAATCATAAAAGTATTTTCAGCCGATGAAAA
TTTTGATTTTGAAATTATAAAACCTTTCGAACCATTCTGCGATTATTTTCTATTTGATACAAAAGGAAAACTACCCGGCG
GTAATGGAACAACTTTCGACTGGAGCATATTAAAAAAATACAATTCGAAAAAGCCTTTCTTTTTAAGCGGCGGTATTGGA
ATGAAAGAATTAAAAGCCATCGAAGAAATTTCAAAAAGCAGTTTACCTATTTATGCAGTCGATGTAAATAGTAAATTTGA
AATTGAACCTGGGCTGAAAAACAGAAATTTATTTAGCAATTTCAAACGAAAATTTGATGTTGCCAACTTTTAA

Upstream 100 bases:

>100_bases
GCTGTAAGCCGTAAGCTATAAGCAAAAAGTAAATAAAAAAATCAGCACAAAGCAAAAAGCCTATTGCCTATTGCCTAAAG
CTTAAAGCAGTATAAAAAAA

Downstream 100 bases:

>100_bases
AATTTAAAAAAATGAGTTTTAACGTTAACGAAAAAGGATATTACGGGGAATTTGGAGGAGCTTACATTCCAGAAATGTTA
TATCCGAATGTAGAAGAACT

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKLKICGMKYPENILEVGALLPDYMGFIFWEKSARYFNGTIPELIKTIKKVGVFVNQSLEEILEKVVKHNLQAVQLHGNE
SVEFVSELKKQLSKKIEIIKVFSADENFDFEIIKPFEPFCDYFLFDTKGKLPGGNGTTFDWSILKKYNSKKPFFLSGGIG
MKELKAIEEISKSSLPIYAVDVNSKFEIEPGLKNRNLFSNFKRKFDVANF

Sequences:

>Translated_210_residues
MKLKICGMKYPENILEVGALLPDYMGFIFWEKSARYFNGTIPELIKTIKKVGVFVNQSLEEILEKVVKHNLQAVQLHGNE
SVEFVSELKKQLSKKIEIIKVFSADENFDFEIIKPFEPFCDYFLFDTKGKLPGGNGTTFDWSILKKYNSKKPFFLSGGIG
MKELKAIEEISKSSLPIYAVDVNSKFEIEPGLKNRNLFSNFKRKFDVANF
>Mature_210_residues
MKLKICGMKYPENILEVGALLPDYMGFIFWEKSARYFNGTIPELIKTIKKVGVFVNQSLEEILEKVVKHNLQAVQLHGNE
SVEFVSELKKQLSKKIEIIKVFSADENFDFEIIKPFEPFCDYFLFDTKGKLPGGNGTTFDWSILKKYNSKKPFFLSGGIG
MKELKAIEEISKSSLPIYAVDVNSKFEIEPGLKNRNLFSNFKRKFDVANF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=205, Percent_Identity=28.2926829268293, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24116; Mature: 24116

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKICGMKYPENILEVGALLPDYMGFIFWEKSARYFNGTIPELIKTIKKVGVFVNQSLE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EILEKVVKHNLQAVQLHGNESVEFVSELKKQLSKKIEIIKVFSADENFDFEIIKPFEPFC
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEECCCHHHH
DYFLFDTKGKLPGGNGTTFDWSILKKYNSKKPFFLSGGIGMKELKAIEEISKSSLPIYAV
CEEEECCCCCCCCCCCCEEHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
DVNSKFEIEPGLKNRNLFSNFKRKFDVANF
ECCCEEEECCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLKICGMKYPENILEVGALLPDYMGFIFWEKSARYFNGTIPELIKTIKKVGVFVNQSLE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EILEKVVKHNLQAVQLHGNESVEFVSELKKQLSKKIEIIKVFSADENFDFEIIKPFEPFC
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEECCCHHHH
DYFLFDTKGKLPGGNGTTFDWSILKKYNSKKPFFLSGGIGMKELKAIEEISKSSLPIYAV
CEEEECCCCCCCCCCCCEEHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
DVNSKFEIEPGLKNRNLFSNFKRKFDVANF
ECCCEEEECCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA