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The map label for this gene is murQ [H]

Identifier: 146302544

GI number: 146302544

Start: 5830057

End: 5830884

Strand: Direct

Name: murQ [H]

Synonym: Fjoh_4817

Alternate gene names: 146302544

Gene position: 5830057-5830884 (Clockwise)

Preceding gene: 146302543

Following gene: 146302545

Centisome position: 95.62

GC content: 37.08

Gene sequence:

>828_bases
ATGAAAAATAAAAATCCTGAAACTGAACAAGAATCTTTGTACAAAGACTTGGATCAAATGAGCGTGAAAGAACTTCTTAC
TAACATCAACACAGAAGACAAAAAAGTACCCCATATTATTGAAGAACAAATTCCAAAAATTGAAAAACTGGTTAAAGCGA
TCGTAAAAAAAATGCAGCTTGGAGGCCGATTATTTTATATTGGAGCCGGAACTTCGGGACGTATTGGTATTTTAGATGCA
TCAGAATGTCCGCCTACTTTTGGCGTACCGCATGATATGATAATCGGAATCATTGCCGGAGGTGACACCGCCATACGCAA
AGCAGTTGAAAATGCTGAAGATGATACAGAACAGGCATGGAAGGATTTAGCCAAGTTTGAAATTTCAAGTCTGGATATGA
TTATTGGAATTGCCGCTTCTGGAAACACGCCGTATGTTTTGGGAGCTTTGAAAAAAGCGAAAGAACACAATATTAAAACA
GGAAGTATTTCCTGCATCAGCAACGGACTTATTGCTCAGGAAGCTGATTATCCGATTGAATTAATTGTAGGACCGGAATT
CTTAACAGGAAGTACAAGAATGAAAGCTGGAACGGCTCAAAAACTGACTTTAAACATGATTTCTACTTCGGTAATGATAA
AACTGGGGAAAGTAAAAGGCAACAAAATGGTCGATATGCAGCTGTCTAACGAAAAACTGGTAAAGCGAGGCATTAAAATG
ATTATGGAAGAACTAAACATTGAATATGATTTAGCCGAAGAATTACTGCACAAACACAAAAGCGTAAGAGCTGTTTTATT
AGCTCAAAACAAAAATCAGGAAATCTAA

Upstream 100 bases:

>100_bases
CAAACCGACTACTTTACACAAAAGTAGAGGAACCTCATACAAAATATCGAAATCATAAATATCAAAATCTGCTGTTTCAA
AATCAAAAAAGAAAAGAAAA

Downstream 100 bases:

>100_bases
AAACTGCAGTATTTAATTAAACACATAGCAACATAGATCTAACACTATAAAAAAGGCGTTTCACTTATTTAAACACACAG
AGACAGCTATGAGTTAGAAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKNKNPETEQESLYKDLDQMSVKELLTNINTEDKKVPHIIEEQIPKIEKLVKAIVKKMQLGGRLFYIGAGTSGRIGILDA
SECPPTFGVPHDMIIGIIAGGDTAIRKAVENAEDDTEQAWKDLAKFEISSLDMIIGIAASGNTPYVLGALKKAKEHNIKT
GSISCISNGLIAQEADYPIELIVGPEFLTGSTRMKAGTAQKLTLNMISTSVMIKLGKVKGNKMVDMQLSNEKLVKRGIKM
IMEELNIEYDLAEELLHKHKSVRAVLLAQNKNQEI

Sequences:

>Translated_275_residues
MKNKNPETEQESLYKDLDQMSVKELLTNINTEDKKVPHIIEEQIPKIEKLVKAIVKKMQLGGRLFYIGAGTSGRIGILDA
SECPPTFGVPHDMIIGIIAGGDTAIRKAVENAEDDTEQAWKDLAKFEISSLDMIIGIAASGNTPYVLGALKKAKEHNIKT
GSISCISNGLIAQEADYPIELIVGPEFLTGSTRMKAGTAQKLTLNMISTSVMIKLGKVKGNKMVDMQLSNEKLVKRGIKM
IMEELNIEYDLAEELLHKHKSVRAVLLAQNKNQEI
>Mature_275_residues
MKNKNPETEQESLYKDLDQMSVKELLTNINTEDKKVPHIIEEQIPKIEKLVKAIVKKMQLGGRLFYIGAGTSGRIGILDA
SECPPTFGVPHDMIIGIIAGGDTAIRKAVENAEDDTEQAWKDLAKFEISSLDMIIGIAASGNTPYVLGALKKAKEHNIKT
GSISCISNGLIAQEADYPIELIVGPEFLTGSTRMKAGTAQKLTLNMISTSVMIKLGKVKGNKMVDMQLSNEKLVKRGIKM
IMEELNIEYDLAEELLHKHKSVRAVLLAQNKNQEI

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=241, Percent_Identity=47.7178423236515, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30272; Mature: 30272

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKNPETEQESLYKDLDQMSVKELLTNINTEDKKVPHIIEEQIPKIEKLVKAIVKKMQL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GGRLFYIGAGTSGRIGILDASECPPTFGVPHDMIIGIIAGGDTAIRKAVENAEDDTEQAW
CCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCHHHHHHHHHCCCCHHHHHH
KDLAKFEISSLDMIIGIAASGNTPYVLGALKKAKEHNIKTGSISCISNGLIAQEADYPIE
HHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHCCCEEECCCCCEE
LIVGPEFLTGSTRMKAGTAQKLTLNMISTSVMIKLGKVKGNKMVDMQLSNEKLVKRGIKM
EEECCCEECCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCEEEEEEECHHHHHHHHHHH
IMEELNIEYDLAEELLHKHKSVRAVLLAQNKNQEI
HHHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCCC
>Mature Secondary Structure
MKNKNPETEQESLYKDLDQMSVKELLTNINTEDKKVPHIIEEQIPKIEKLVKAIVKKMQL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GGRLFYIGAGTSGRIGILDASECPPTFGVPHDMIIGIIAGGDTAIRKAVENAEDDTEQAW
CCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCHHHHHHHHHCCCCHHHHHH
KDLAKFEISSLDMIIGIAASGNTPYVLGALKKAKEHNIKTGSISCISNGLIAQEADYPIE
HHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHCCCEEECCCCCEE
LIVGPEFLTGSTRMKAGTAQKLTLNMISTSVMIKLGKVKGNKMVDMQLSNEKLVKRGIKM
EEECCCEECCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCEEEEEEECHHHHHHHHHHH
IMEELNIEYDLAEELLHKHKSVRAVLLAQNKNQEI
HHHHHCCCHHHHHHHHHHHHHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA