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The map label for this gene is sglT [H]

Identifier: 146302545

GI number: 146302545

Start: 5831213

End: 5832718

Strand: Direct

Name: sglT [H]

Synonym: Fjoh_4818

Alternate gene names: 146302545

Gene position: 5831213-5832718 (Clockwise)

Preceding gene: 146302544

Following gene: 146302546

Centisome position: 95.64

GC content: 33.33

Gene sequence:

>1506_bases
ATGACACCAACTACCATTCTTCTCCTTATTATCGTTTATTTCGGAACCCTATTCTATATCTCACACAGAGTGAGCAGAAA
AGACAGCGGAAATGATGCTTTTTTTACAGCCAATAAAAACTCCAAATGGTATTTAGTTGCTTTTGGAATGATTGGAACTG
CTCTTTCCGGAGTAACCTTTATATCCGTTCCCGGAGAAGTTGGCGCACCAAGCGGTGAACAATTCAAATATTTTCAGTTC
GTTTTAGGAAATGCTCTTGGTTTTATTGTAATCACAAAACTATTGCTGCCGTTGTATTACCGAATGAACCTGACTTCAAT
TTATGGTTATATTGAACAAAGAATGGGGCTTTACAGTTACAAAACTGCCGCTTCTATTTTCTTAATCAGCAGAACCATAA
GTTCAGCATTCAGGCTTTATCTTGTTGTAATTGTATTGCAGCGTTTTGTATTCGATTACTTTCATATTCCATTTGCCTTG
ACAGTATTAATCTCTTTACTGCTTATTTTCTCTTATACGTACAGAGGCGGATTAAAAACGATTATTATTACTGATACTTT
ACAAACGTTTTTTCTAGTAACATCAGTTTTTCTTACTATTTATTTCATCTGCGACCGTATGGATTTAAGTGCCATCAGCG
CATTTGAAGAAGTAAAAAACAGCAACTATTCTAAAATATTTTTCTTTGATGATTTCTTCGGAAGCAAATTCCATTTTGTA
AAACAAATTTTAGGCGGAATGTTCGTAACCATCGCCATGACAGGTCTGGATCAGGATTTAATGCAAAAAAACCTGAGCTG
TAAAAACATTGGCGAAGCACAAAAAAATATGTTCACTTTTACAGGAATCTTTGTAGTTATTAATATTTTCTTTTTAAGTG
TTGGAGCTCTATTATATATTTATGCTAATAAAAACGGAATCGCTATTCCAACTGATTTAGTTACAGGAAAACCCAGAACC
GATTTACTCTTTCCTGAAATTGCCTTAAATCATTTAGCAGTAGTTCCAGCCATTGTGTTTTTACTGGGAATTATCGCGGC
GACTTTTGCCACAACAGATTCGGCATTAACAGCTTTAACAACTTCTTTTTGTGTTGACTTTTTAGGAATGGATAAAAGTG
AAAATACCAAAAAAAATACCGTTAGAACCAGACATTTAGTACACATCAGTTTTTCGGTATTAATTTTCTTTGTCATTATT
ATTTTCAATACCATCAACGACAGTTCTGTTGTGGGAATGATTTTCAAAGTTGCTTCTTATACTTACGGTCCATTATTAGG
GTTATATGCTTTTGGATTGTTCCAAAAATCAAGATATGTAAACGATAAGTTAGTACCGTTTATTTGTCTCTTGGCTCCTT
TCCTAACCTATTTAATAAATGAAAACTCGAAACTATTATTTTCAGGATATGTTTTTGACAATGAGTTAATTGTACTGAAC
GGATTAATCACCTATTTAGGATTATATATAACAAGTTCTCGAAGCCACGAAAAAATAAGTTTTTAA

Upstream 100 bases:

>100_bases
AGTTTTTAACGGCGACCTGACCGATTAACAATCTGTCAGGTCAAATTAAAATCCGTTATTTGAATAAATTATAAAAAACC
AAAACCACCAAAACTATAAA

Downstream 100 bases:

>100_bases
TCGGTTTAAAAACGCAAATAATTTACCCAGCCAATTGACGTTTAAAACAAAACTTCAATTGATTCAAAAAAAATAGTATG
AAAGATTACATCATAAAGAT

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTPTTILLLIIVYFGTLFYISHRVSRKDSGNDAFFTANKNSKWYLVAFGMIGTALSGVTFISVPGEVGAPSGEQFKYFQF
VLGNALGFIVITKLLLPLYYRMNLTSIYGYIEQRMGLYSYKTAASIFLISRTISSAFRLYLVVIVLQRFVFDYFHIPFAL
TVLISLLLIFSYTYRGGLKTIIITDTLQTFFLVTSVFLTIYFICDRMDLSAISAFEEVKNSNYSKIFFFDDFFGSKFHFV
KQILGGMFVTIAMTGLDQDLMQKNLSCKNIGEAQKNMFTFTGIFVVINIFFLSVGALLYIYANKNGIAIPTDLVTGKPRT
DLLFPEIALNHLAVVPAIVFLLGIIAATFATTDSALTALTTSFCVDFLGMDKSENTKKNTVRTRHLVHISFSVLIFFVII
IFNTINDSSVVGMIFKVASYTYGPLLGLYAFGLFQKSRYVNDKLVPFICLLAPFLTYLINENSKLLFSGYVFDNELIVLN
GLITYLGLYITSSRSHEKISF

Sequences:

>Translated_501_residues
MTPTTILLLIIVYFGTLFYISHRVSRKDSGNDAFFTANKNSKWYLVAFGMIGTALSGVTFISVPGEVGAPSGEQFKYFQF
VLGNALGFIVITKLLLPLYYRMNLTSIYGYIEQRMGLYSYKTAASIFLISRTISSAFRLYLVVIVLQRFVFDYFHIPFAL
TVLISLLLIFSYTYRGGLKTIIITDTLQTFFLVTSVFLTIYFICDRMDLSAISAFEEVKNSNYSKIFFFDDFFGSKFHFV
KQILGGMFVTIAMTGLDQDLMQKNLSCKNIGEAQKNMFTFTGIFVVINIFFLSVGALLYIYANKNGIAIPTDLVTGKPRT
DLLFPEIALNHLAVVPAIVFLLGIIAATFATTDSALTALTTSFCVDFLGMDKSENTKKNTVRTRHLVHISFSVLIFFVII
IFNTINDSSVVGMIFKVASYTYGPLLGLYAFGLFQKSRYVNDKLVPFICLLAPFLTYLINENSKLLFSGYVFDNELIVLN
GLITYLGLYITSSRSHEKISF
>Mature_500_residues
TPTTILLLIIVYFGTLFYISHRVSRKDSGNDAFFTANKNSKWYLVAFGMIGTALSGVTFISVPGEVGAPSGEQFKYFQFV
LGNALGFIVITKLLLPLYYRMNLTSIYGYIEQRMGLYSYKTAASIFLISRTISSAFRLYLVVIVLQRFVFDYFHIPFALT
VLISLLLIFSYTYRGGLKTIIITDTLQTFFLVTSVFLTIYFICDRMDLSAISAFEEVKNSNYSKIFFFDDFFGSKFHFVK
QILGGMFVTIAMTGLDQDLMQKNLSCKNIGEAQKNMFTFTGIFVVINIFFLSVGALLYIYANKNGIAIPTDLVTGKPRTD
LLFPEIALNHLAVVPAIVFLLGIIAATFATTDSALTALTTSFCVDFLGMDKSENTKKNTVRTRHLVHISFSVLIFFVIII
FNTINDSSVVGMIFKVASYTYGPLLGLYAFGLFQKSRYVNDKLVPFICLLAPFLTYLINENSKLLFSGYVFDNELIVLNG
LITYLGLYITSSRSHEKISF

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI157671931, Length=440, Percent_Identity=23.1818181818182, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4507035, Length=441, Percent_Identity=20.6349206349206, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI167466278, Length=414, Percent_Identity=22.9468599033816, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI256985183, Length=433, Percent_Identity=21.9399538106236, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24640370, Length=455, Percent_Identity=23.5164835164835, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573698, Length=462, Percent_Identity=22.5108225108225, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221459584, Length=467, Percent_Identity=21.1991434689507, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28574994, Length=389, Percent_Identity=26.2210796915167, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221459582, Length=453, Percent_Identity=22.2958057395143, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221459588, Length=434, Percent_Identity=21.4285714285714, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221459586, Length=442, Percent_Identity=21.0407239819005, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641117, Length=436, Percent_Identity=23.8532110091743, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24650192, Length=429, Percent_Identity=21.4452214452214, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24645928, Length=457, Percent_Identity=21.0065645514223, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651739, Length=430, Percent_Identity=20.9302325581395, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 56366; Mature: 56235

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTTILLLIIVYFGTLFYISHRVSRKDSGNDAFFTANKNSKWYLVAFGMIGTALSGVTF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHCCCEE
ISVPGEVGAPSGEQFKYFQFVLGNALGFIVITKLLLPLYYRMNLTSIYGYIEQRMGLYSY
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KTAASIFLISRTISSAFRLYLVVIVLQRFVFDYFHIPFALTVLISLLLIFSYTYRGGLKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IIITDTLQTFFLVTSVFLTIYFICDRMDLSAISAFEEVKNSNYSKIFFFDDFFGSKFHFV
EEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
KQILGGMFVTIAMTGLDQDLMQKNLSCKNIGEAQKNMFTFTGIFVVINIFFLSVGALLYI
HHHHCHHEEEHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
YANKNGIAIPTDLVTGKPRTDLLFPEIALNHLAVVPAIVFLLGIIAATFATTDSALTALT
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TSFCVDFLGMDKSENTKKNTVRTRHLVHISFSVLIFFVIIIFNTINDSSVVGMIFKVASY
HHHHHHHHCCCCCCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TYGPLLGLYAFGLFQKSRYVNDKLVPFICLLAPFLTYLINENSKLLFSGYVFDNELIVLN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEHH
GLITYLGLYITSSRSHEKISF
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TPTTILLLIIVYFGTLFYISHRVSRKDSGNDAFFTANKNSKWYLVAFGMIGTALSGVTF
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHCCCEE
ISVPGEVGAPSGEQFKYFQFVLGNALGFIVITKLLLPLYYRMNLTSIYGYIEQRMGLYSY
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KTAASIFLISRTISSAFRLYLVVIVLQRFVFDYFHIPFALTVLISLLLIFSYTYRGGLKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IIITDTLQTFFLVTSVFLTIYFICDRMDLSAISAFEEVKNSNYSKIFFFDDFFGSKFHFV
EEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
KQILGGMFVTIAMTGLDQDLMQKNLSCKNIGEAQKNMFTFTGIFVVINIFFLSVGALLYI
HHHHCHHEEEHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
YANKNGIAIPTDLVTGKPRTDLLFPEIALNHLAVVPAIVFLLGIIAATFATTDSALTALT
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TSFCVDFLGMDKSENTKKNTVRTRHLVHISFSVLIFFVIIIFNTINDSSVVGMIFKVASY
HHHHHHHHCCCCCCCCHHHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TYGPLLGLYAFGLFQKSRYVNDKLVPFICLLAPFLTYLINENSKLLFSGYVFDNELIVLN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEHH
GLITYLGLYITSSRSHEKISF
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]